Green Tea Aids in Overall Health

Green tea is highly effective in aiding in overall health if consumed on a daily basis and can reduce incidence of cardiovascular disease, obesity, type 2 diabetes, and certain types of cancer. The primary compounds found in green tea are polyphenols which include catechins, epicatechin(EC), epigallocatechin(EGC), epicatechingallate(ECG), andepigallocatechingallate(EGCG). Five research studies were analyzed to verify the validity of the hypothesis that green consumption is beneficial in overall health. In these studies, green tea was found to aid in weight loss with those who consumed green tea regularly, as well as having effects on thermogenesis and fat oxidation to control wait maintenance. There was also a beneficial inverse association between green tea, coffee, and caffeine consumption and the risk of diabetes, cardiovascular disease, and mortality rates. The EGCG in the green tea was considered to be the primary ingredient that reduced mortality rates. Green tea is known to contain powerful antioxidants that help fight off diseases such as cancer. Green tea was statistically proven to contain the highest antioxidant content compared to other teas such as black tea, oolong tea, and roasted tea (

Green Tea Polyphenol Epigallocatechin-3-Gallate Enhance Glycogen Synthesis and Inhibit Lipogenesis in Hepatocytes

The beneficial effects of green tea polyphenols (GTP) against metabolic syndrome and type 2 diabetes by suppressing appetite and nutrient absorption have been well reported. However the direct effects and mechanisms of GTP on glucose and lipid metabolis

Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management

Functional foods contain biologically active ingredients associated with physiological health benefits for preventing and managing chronic diseases, such as type 2 diabetes mellitus (T2DM). A regular consumption of functional foods may be associated with enhanced anti-oxidant, anti-inflammatory, insulin sensitivity, and anti-cholesterol functions, which are considered integral to prevent and manage T2DM. Components of the Mediterranean diet (MD)—such as fruits, vegetables, oily fish, olive oil, and tree nuts—serve as a model for functional foods based on their natural contents of nutraceuticals, including polyphenols, terpenoids, flavonoids, alkaloids, sterols, pigments, and unsaturated fatty acids. Polyphenols within MD and polyphenol-rich herbs—such as coffee, green tea, black tea, and yerba maté—have shown clinically-meaningful benefits on metabolic and microvascular activities, cholesterol and fasting glucose lowering, and anti-inflammation and anti-oxidation in high-risk and T2DM patients. However, combining exercise with functional food consumption can trigger and augment several metabolic and cardiovascular protective benefits, but it is under-investigated in people with T2DM and bariatric surgery patients. Detecting functional food benefits can now rely on an “omics” biological profiling of individuals’ molecular, genetics, transcriptomics, proteomics, and metabolomics, but is under-investigated in multi-component interventions. A personalized approach for preventing and managing T2DM should consider biological and behavioral models, and embed nutrition education as part of lifestyle diabetes prevention studies. Functional foods may provide additional benefits in such an approach

Polyphenols as Suitable control for Obesity and Diabetes

Modern life is characterized by physical inactivity and poor food choices, which is often a prerequisite for unhealthy weight gain and overweight/obesity. These factors unlock the emergence of a number of diseases including diabetes, cardiovascular problems, different types of cancer, etc. The pursuit of scientists to seek strategies to prevent, relieve and cure the patient leads to the usage of natural compounds of potential beneficial effect. Polyphenols are a large group of naturally occurring secondary metabolites mainly found in plants and beverages. The presence of these secondary metabolites seems to decrease the manifestation of miscellaneous disease-causing symptoms. The purpose of this review is to synthesize information about polyphenols and their potential in controlling obesity and diabetes. Polyphenols are considered as health-beneficial sources and thus could be involved in novel strategies for preventing diabetes and obesity complications

Dietary factors and Type 2 diabetes in the Middle East : what is the evidence for an association? - A systematic review.

This review aims to search and summarise the available evidence on the association between dietary factors and type 2 diabetes mellitus (T2DM) in Middle Eastern populations, where diabetes prevalence is among the highest in the world. Electronic databases were searched; authors, libraries, and research centres in the Middle East were contacted for further studies and unpublished literature. Included studies assessed potential dietary factors for T2DM in Middle Eastern adults. Two reviewers assessed studies independently. Extensive searching yielded 17 studies which met the inclusion criteria for this review. The findings showed that whole-grain intake reduces the risk of T2DM, and potato consumption was positively correlated with T2DM. Vegetables and vegetable oil may play a protective role against T2DM. Dietary patterns that are associated with diabetes were identified, such as Fast Food and Refined Grains patterns. Two studies demonstrated that lifestyle interventions decreased the risk of T2DM. In summary, the identified studies support an association between some dietary factors and T2DM; however, many of the included studies were of poor methodological quality so the findings should be interpreted with caution. The review draws attention to major gaps in current evidence and the need for well-designed studies in this area

The Influence of Sugar-Sweetened Beverage Health Warning Labels on Parents' Choices

US states have introduced bills requiring sugar-sweetened beverages (SSBs) to display health warning labels. This study examined how such labels may influence parents and which labels are most impactful. In an online survey of 2381 demographically and educationally diverse parents, SSB health warning labels improved parents understanding of health harms associated with overconsumption of SSBs. The warning labels also lowered parents' intentions to purchase SSBs for their children

Prospective study of coffee and tea consumption in relation to risk of type 2 diabetes mellitus among men and women: The Whitehall II study

At least fourteen cohort studies have documented all inverse association between coffee consumption and risk of type 2 diabetes. We examined the prospective association between coffee and tea consumption and the risk of type 2 diabetes mellitus among British men (n 4055) and women (n 1768) from the Whitehall II cohort. During 11.7 years follow-up there were a total of 387 incident cases of diabetes confirmed by Self-report of doctor's diagnosis or glucose tolerance tests. Despite an inverse association between coffee intake and 2 h post-load glucose concentration at the baseline assessment, combined caffeinated and decaffeinated coffee (hazard ratio (HR) 0-80 95% CI 0.54, 1.18) or only decaffeinated coffee intake (HR 0.65: 95% CI 0.36, 1.16) was not significantly associated with diabetes risk at follow-up after adjustment for possible confounders. There was all association between tea intake and diabetes (HR 0.66: 95% CI 0.61, 1.22: P<0.05) after adjustment for age. gender. ethnicity and social status, which was not robust to further adjustments. There was. however, an association between combined intake of tea and coffee (two or more cups per clay of both beverage) and diabetes (HR 0.68: 95% CI 0.46, 0.99: P<0.05) after full adjustment. In conclusion, relatively moderate intake (more than three CLIPS per (lay) of coffee and tea were not prospectively associated with incidence of type 2 diabetes although there was evidence of a combined effect. The limited range of exposure and beverage consumption according to socio-economic class may explain these conflicting findings

Pathogenesis of AD is similar to that of uremic encephalopathy of Homocysteic acid.

Homocysteic acid (HA) has been established as a pathogen in Alzheimer&#x27;s disease (AD) in 3xTg-AD model mice. However, it is not established whether HA is involved in the AD pathogenesis in humans. We investigated the relationship between urinary HA levels and Mini-Mental State Examination (MMSE) scores in patients with AD (n = 110, normal =22, AD=88) and found a positive, statistically significant relationship between the two variables (r = 0.39, p =0.00003, n = 110). This relationship was stronger in females. (r = 0.47, p = 0.00008, n = 65 in females; r = 0.39, p = 0.02, n =45 in males). The difference in the urinary HA level between normal and AD females was statistically significant (normal:18.4 + 10.6vsAD: 9.1 + 7.2 mM,p&#x3c;0.01), but this difference in males was not statistically significant. (normal:12.7 + 6 vs AD8.8 + 7.8). Smoking, hypertension, and diabetes mellitus decreased urinary HA excretion. On the basis of these results, we showed that HA is usually excreted into urine in humans and did not affect brain function in normal individuals. However, when urinary HA excretion was decreased, HA was shown to damage brain function, particularly cognitive ability. To confirm our hypothesis, that is, when urinary HA is suppressed to be excreted into urine, the blood HA level will increase, we examined the relationship between the urinary HA level and blood HA level in 19 patients. The result was shown that the negative statistically significant relationship between them was observed (r=-0.6, p=0.007, n=19). From this result, the uremic encephalopathy of HA toxicity was confirmed. However there remains the question of how the blood HA affected the brain&#x27;s cognitive function. The direct effect of green tea leaves ingestion on HA level and MMSE score were also observed. Ingested green tea leaves decreased HA level in blood and concomitantly increased MMSE score, suggesting that blood HA could affect cognitive function. But How? Some papers showed that exogenous NMDA including HA disrupted the blood brain barrier and entered into the brain and affected the cognitive function to decrease MMSE score. These results indicate that human AD pathogenesis is influenced by HA, and that HA is a human pathogen in AD, indicating that the pathogenesis of AD is similar to that of uremic encephalopathy. Also, urinary HA can be used as a biomarker for Alzheimer&#x27;s disease