Multi-input distributed classifiers for synthetic genetic circuits

For practical construction of complex synthetic genetic networks able to perform elaborate functions it is important to have a pool of relatively simple "bio-bricks" with different functionality which can be compounded together. To complement engineering of very different existing synthetic genetic devices such as switches, oscillators or logical gates, we propose and develop here a design of synthetic multiple input distributed classifier with learning ability. Proposed classifier will be able to separate multi-input data, which are inseparable for single input classifiers. Additionally, the data classes could potentially occupy the area of any shape in the space of inputs. We study two approaches to classification, including hard and soft classification and confirm the schemes of genetic networks by analytical and numerical results

Discrete and fuzzy dynamical genetic programming in the XCSF learning classifier system

A number of representation schemes have been presented for use within learning classifier systems, ranging from binary encodings to neural networks. This paper presents results from an investigation into using discrete and fuzzy dynamical system representations within the XCSF learning classifier system. In particular, asynchronous random Boolean networks are used to represent the traditional condition-action production system rules in the discrete case and asynchronous fuzzy logic networks in the continuous-valued case. It is shown possible to use self-adaptive, open-ended evolution to design an ensemble of such dynamical systems within XCSF to solve a number of well-known test problems

Design for novel enhanced weightless neural network and multi-classifier.

Weightless neural systems have often struggles in terms of speed, performances, and memory issues. There is also lack of sufficient interfacing of weightless neural systems to others systems. Addressing these issues motivates and forms the aims and objectives of this thesis. In addressing these issues, algorithms are formulated, classifiers, and multi-classifiers are designed, and hardware design of classifier are also reported. Specifically, the purpose of this thesis is to report on the algorithms and designs of weightless neural systems. A background material for the research is a weightless neural network known as Probabilistic Convergent Network (PCN). By introducing two new and different interfacing method, the word "Enhanced" is added to PCN thereby giving it the name Enhanced Probabilistic Convergent Network (EPCN). To solve the problem of speed and performances when large-class databases are employed in data analysis, multi-classifiers are designed whose composition vary depending on problem complexity. It also leads to the introduction of a novel gating function with application of EPCN as an intelligent combiner. For databases which are not very large, single classifiers suffices. Speed and ease of application in adverse condition were considered as improvement which has led to the design of EPCN in hardware. A novel hashing function is implemented and tested on hardware-based EPCN. Results obtained have indicated the utility of employing weightless neural systems. The results obtained also indicate significant new possible areas of application of weightless neural systems

Characterization of Mammogram Using Ensemble Classification Technique for Detection of Breast Cancer

Breast cancer is one of the most common known cancers in women today. Just like any other form of cancer an early detection of cancer provides better chances of cure. However, it is an arduous task for the radiologists to detect cancer accurately. Thus computer aided diagnosis of the mammographic images is the most popular medium to aid the radiologists in accurately classifying benign and malignant mammographic lesions. In this thesis an efficient approach is presented to classify the mammographic lesion for the detection of breast cancer. In this approach the extracted feature coefficients are balanced using Gaussian distribution. This distribution balances the class unbalanced dataset providing for better classification. This scheme uses Logit Boost classification technique. Logit Boost uses least squared regression cost function on the additive model of Adaboost. The standard MIAS database was used to obtain the mammographic lesions. With a classification accuracy rate of 99.1% and a performance index value of AUC = 0.98 in receiver operating characteristic (ROC) curve the results are pretty much optimal. These results are very promising when compared with existing methods