MedGAN: Medical Image Translation using GANs

Image-to-image translation is considered a new frontier in the field of medical image analysis, with numerous potential applications. However, a large portion of recent approaches offers individualized solutions based on specialized task-specific architectures or require refinement through non-end-to-end training. In this paper, we propose a new framework, named MedGAN, for medical image-to-image translation which operates on the image level in an end-to-end manner. MedGAN builds upon recent advances in the field of generative adversarial networks (GANs) by merging the adversarial framework with a new combination of non-adversarial losses. We utilize a discriminator network as a trainable feature extractor which penalizes the discrepancy between the translated medical images and the desired modalities. Moreover, style-transfer losses are utilized to match the textures and fine-structures of the desired target images to the translated images. Additionally, we present a new generator architecture, titled CasNet, which enhances the sharpness of the translated medical outputs through progressive refinement via encoder-decoder pairs. Without any application-specific modifications, we apply MedGAN on three different tasks: PET-CT translation, correction of MR motion artefacts and PET image denoising. Perceptual analysis by radiologists and quantitative evaluations illustrate that the MedGAN outperforms other existing translation approaches.Comment: 16 pages, 8 figure

Adversarial nets with perceptual losses for text-to-image synthesis

Recent approaches in generative adversarial networks (GANs) can automatically synthesize realistic images from descriptive text. Despite the overall fair quality, the generated images often expose visible flaws that lack structural definition for an object of interest. In this paper, we aim to extend state of the art for GAN-based text-to-image synthesis by improving perceptual quality of generated images. Differentiated from previous work, our synthetic image generator optimizes on perceptual loss functions that measure pixel, feature activation, and texture differences against a natural image. We present visually more compelling synthetic images of birds and flowers generated from text descriptions in comparison to some of the most prominent existing work