2,397 research outputs found
Competing and Learning in Global Value Chains - Firms’ Experiences in the Case of Uganda. A study of five export sub-sectors with reference to trade between Uganda and Europe
Executive Summary and Chapter 5: Presentation and discussion of main finding
Beyond harsh trade? The relevance of ‘soft’ competitiveness factors for Ugandan enterprises to endure in Global Value Chains
This article is based on an empirical study which examined the issues
of organization and coordination of global production and trade for the
case of trade between Uganda and Europe.Respective experiences of
34 exporters in Uganda and 19 importers in Europe were documented
through in-depth interviews and consequently analyzed. The article
discusses matters of cooperation between the exporters and importers and
points to its significance for upgrading and enhancing competitiveness of
the exporters studied. It further identifies firm level ‘soft competitiveness
factors’ (SCFs) of Ugandan exporters and discusses their relevance
for the firms’ performance in Global Value Chains. The findings reveal
that deficiencies in SCFs can have damaging effects, and vice-versa.
Possession of the SCFs can yield significant competitive advantage for
exporters and help to strengthen the relationship with the importers.
Findings of ill-treatment of exporters by their importers highlight a
particular kind of challenge that is often overseen in the debate about
exports of African firms: the challenge regarding business behaviours,
practices, and ethics including the ability to engage in relations with
foreign buyers and leverage resources, knowledge and generally
cooperation from them, first, and the general issue of problematic business
practices in the global economy, second. The article policy recommends
Policy, practice and research should focus on economic, political, social,
cultural and institutional factors that impact on local levels of SCFs; to
improve and help exporting enterprises in Africa to survive and succeed
in GVCs, within the context of the state of the moral economy in global
capitalism
Measuring trade in value added with Firm-Level Data. NBB Working Paper No 378, November 2019
Global Value Chains have proliferated economic policy debates. Yet a key concept – trade in value
added –is likely mismeasured because of sectoral aggregation bias stemming from reliance on inputoutput
tables. This paper uses comprehensive firm-level data on both domestic and international
transactions to study this bias. We find that sectoral aggregation leads to overstated trade in value
added and, correspondingly, understated import content of gross exports. The economic magnitude
of the estimated bias varies from moderate to large – at 2-5 p.p. of gross exports for Belgium and
17 p.p. for China. We study how the interplay between within-sector heterogeneities in firm import
and export intensities and firm size determine the magnitude of the sectoral aggregation bias
Pharmacological levels of withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells
Withaferin A (WA) isolated from Withania somnifera (Ashwagandha) has recently become an attractive phytochemical under investigation in various preclinical studies for treatment of different cancer types. In the present study, a comparative pathway-based transcriptome analysis was applied in epithelial-like MCF-7 and triple negative mesenchymal MDA-MB-231 breast cancer cells exposed to different concentrations of WA which can be detected systemically in in vivo experiments. Whereas WA treatment demonstrated attenuation of multiple cancer hallmarks, the withanolide analogue Withanone (WN) did not exert any of the described effects at comparable concentrations. Pathway enrichment analysis revealed that WA targets specific cancer processes related to cell death, cell cycle and proliferation, which could be functionally validated by flow cytometry and real-time cell proliferation assays. WA also strongly decreased MDA-MB-231 invasion as determined by single-cell collagen invasion assay. This was further supported by decreased gene expression of extracellular matrix-degrading proteases (uPA, PLAT, ADAM8), cell adhesion molecules (integrins, laminins), pro-inflammatory mediators of the metastasis-promoting tumor microenvironment (TNFSF12, IL6, ANGPTL2, CSF1R) and concomitant increased expression of the validated breast cancer metastasis suppressor gene (BRMS1). In line with the transcriptional changes, nanomolar concentrations of WA significantly decreased protein levels and corresponding activity of uPA in MDA-MB-231 cell supernatant, further supporting its anti-metastatic properties. Finally, hierarchical clustering analysis of 84 chromatin writer-reader-eraser enzymes revealed that WA treatment of invasive mesenchymal MDA-MB-231 cells reprogrammed their transcription levels more similarly towards the pattern observed in non-invasive MCF-7 cells. In conclusion, taking into account that sub-cytotoxic concentrations of WA target multiple metastatic effectors in therapy-resistant triple negative breast cancer, WA-based therapeutic strategies targeting the uPA pathway hold promise for further (pre)clinical development to defeat aggressive metastatic breast cancer
The Impact of Increased Import Competition from the People’s Republic of China on Income Inequality and Household Welfare in Viet Nam
This paper examines the surge of imports from the PRC to Viet Nam from 2000 to 2014 in order to evaluate the effects of increased exposure to trade with the PRC on income inequality and household welfare in Viet Nam. Using household level data from the Viet Nam Household Living Standard Survey and combining it with measures of trade exposure, we find that increased imports led to a fall in inequality at the provincial and district level. We distinguish between intermediate and final goods and find similar results. In order to better understand the relative gains and losses across income groups, we apply a quantile regression approach. Our results indicate that increased imports were more often positively correlated with household income for households located in the lower quantiles. In contrast, for households in the upper quantiles the correlation is either negative or less pronounced
Conserving California Landscapes: Midterm Report
Provides a review at the halfway point of a program that was designed to conserve large expanses of open space, farmlands, and wildlife habitat in three California regions: the Central Coast, the Central Valley, and the Sierra Nevada
Crisis-related changes in the specialization of advanced economies in global value chains
Analysis of globalization-induced gains and losses necessitates not only new types of data to complement that compiled in traditional trade statistics but also new analytical approaches. This article surveys the literature that addresses the evolution of the global value chain approach, an analytical perspective that is able to capture in greater depth than earlier theories the causes and consequences of the ongoing process of global reorganization of production. Our specific focus is, on the one hand, changing activity specialization within the new global division of labour and the related changes in competitiveness of advanced economy actors; and, on the other hand, crisis-related changes in global value chains. We conjecture that advanced economy actors have been continuously shifting their specialization towards ‘the edges of the value chains’ into activities requiring higher skills, which result in the capture of higher value for them. We show that this process has further accelerated during the financial crisis. </jats:p
Conflict and social vulnerability to climate change: Lessons from Gaza
In societies marred by conflict, the propensity of populations to be harmed by climate hazards is likely to be increased by their exposure to violence and other coercive practices. Stakeholder assessments of climate vulnerability, as reported here for the Gaza Strip, can capture the qualitative experience of harm caused by conflict-related practices as these relate to, and interact with, forecasted climatic risks. The key pathways of climate vulnerability identified by stakeholders in Gaza relate above all to expected impacts on food security and water security. Exploration of these vulnerability pathways reveals conflict-structured non-climatic risks overwhelming forecasted climate risks. The prevalence in Gaza of short-term 'enforced coping' prevents the development of long-term adaptive capacity. Climate vulnerability assessments in (post)conflict environments should acknowledge the methodological and political-policy challenges caused by chronic, non-climatic sources of harm. © 2011 Taylor & Francis
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