7,986 research outputs found
SAGE: Sequential Attribute Generator for Analyzing Glioblastomas using Limited Dataset
While deep learning approaches have shown remarkable performance in many
imaging tasks, most of these methods rely on availability of large quantities
of data. Medical image data, however, is scarce and fragmented. Generative
Adversarial Networks (GANs) have recently been very effective in handling such
datasets by generating more data. If the datasets are very small, however, GANs
cannot learn the data distribution properly, resulting in less diverse or
low-quality results. One such limited dataset is that for the concurrent gain
of 19 and 20 chromosomes (19/20 co-gain), a mutation with positive prognostic
value in Glioblastomas (GBM). In this paper, we detect imaging biomarkers for
the mutation to streamline the extensive and invasive prognosis pipeline. Since
this mutation is relatively rare, i.e. small dataset, we propose a novel
generative framework - the Sequential Attribute GEnerator (SAGE), that
generates detailed tumor imaging features while learning from a limited
dataset. Experiments show that not only does SAGE generate high quality tumors
when compared to standard Deep Convolutional GAN (DC-GAN) and Wasserstein GAN
with Gradient Penalty (WGAN-GP), it also captures the imaging biomarkers
accurately
Visual Feature Attribution using Wasserstein GANs
Attributing the pixels of an input image to a certain category is an
important and well-studied problem in computer vision, with applications
ranging from weakly supervised localisation to understanding hidden effects in
the data. In recent years, approaches based on interpreting a previously
trained neural network classifier have become the de facto state-of-the-art and
are commonly used on medical as well as natural image datasets. In this paper,
we discuss a limitation of these approaches which may lead to only a subset of
the category specific features being detected. To address this problem we
develop a novel feature attribution technique based on Wasserstein Generative
Adversarial Networks (WGAN), which does not suffer from this limitation. We
show that our proposed method performs substantially better than the
state-of-the-art for visual attribution on a synthetic dataset and on real 3D
neuroimaging data from patients with mild cognitive impairment (MCI) and
Alzheimer's disease (AD). For AD patients the method produces compellingly
realistic disease effect maps which are very close to the observed effects.Comment: Accepted to CVPR 201
Informative sample generation using class aware generative adversarial networks for classification of chest Xrays
Training robust deep learning (DL) systems for disease detection from medical
images is challenging due to limited images covering different disease types
and severity. The problem is especially acute, where there is a severe class
imbalance. We propose an active learning (AL) framework to select most
informative samples for training our model using a Bayesian neural network.
Informative samples are then used within a novel class aware generative
adversarial network (CAGAN) to generate realistic chest xray images for data
augmentation by transferring characteristics from one class label to another.
Experiments show our proposed AL framework is able to achieve state-of-the-art
performance by using about of the full dataset, thus saving significant
time and effort over conventional methods
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