4 research outputs found

    Finding hypernetworks in directed hypergraphs

    Get PDF
    The term ‘‘hypernetwork’’ (more precisely, s-hypernetwork and (s, d)-hypernetwork) has been recently adopted to denote some logical structures contained in a directed hypergraph. A hypernetwork identifies the core of a hypergraph model, obtained by filtering off redundant components. Therefore, finding hypernetworks has a notable relevance both from a theoretical and from a computational point of view. In this paper we provide a simple and fast algorithm for finding s-hypernetworks, which substantially improves on a method previously proposed in the literature. We also point out two linearly solvable particular cases. Finding an (s, d)-hypernetwork is known to be a hard problem, and only one polynomially solvable class has been found so far. Here we point out that this particular case is solvable in linear time

    Hypergraphs Demonstrate Anastomoses During Divergent Integration

    Full text link
    Complex networks can be used to analyze structures and systems in the embryo. Not only can we characterize growth and the emergence of form, but also differentiation. The process of differentiation from precursor cell populations to distinct functional tissues is of particular interest. These phenomena can be captured using a hypergraph consisting of nodes represented by cell type categories and arranged as a directed cyclic graph (lineage hypergraph) and a complex network (spatial hypergraph). The lineage hypergraph models the developmental process as an n-ary tree, which can model two or more descendent categories per division event. A lineage tree based on the mosaic development of the nematode C. elegans (2-ary tree), is used to capture this process. Each round of divisions produces a new set of categories that allow for exchange of cells between types. An example from single-cell morphogenesis based on the cyanobacterial species Nostoc punctiforme (multiple discontinuous 2-ary tree) is also used to demonstrate the flexibility of this method. This model allows for new structures to emerge (such as a connectome) while also demonstrating how precursor categories are maintained for purposes such as dedifferentiation or other forms of cell fate plasticity. To understand this process of divergent integration, we analyze the directed hypergraph and categorical models, in addition to considering the role of network fistulas (spaces that conjoin two functional modules) and spatial restriction.Comment: 21 pages, 8 figure

    Finding hypernetworks in directed hypergraphs

    No full text
    corecore