5,106 research outputs found
AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks
Segmentation of axon and myelin from microscopy images of the nervous system
provides useful quantitative information about the tissue microstructure, such
as axon density and myelin thickness. This could be used for instance to
document cell morphometry across species, or to validate novel non-invasive
quantitative magnetic resonance imaging techniques. Most currently-available
segmentation algorithms are based on standard image processing and usually
require multiple processing steps and/or parameter tuning by the user to adapt
to different modalities. Moreover, only few methods are publicly available. We
introduce AxonDeepSeg, an open-source software that performs axon and myelin
segmentation of microscopic images using deep learning. AxonDeepSeg features:
(i) a convolutional neural network architecture; (ii) an easy training
procedure to generate new models based on manually-labelled data and (iii) two
ready-to-use models trained from scanning electron microscopy (SEM) and
transmission electron microscopy (TEM). Results show high pixel-wise accuracy
across various species: 85% on rat SEM, 81% on human SEM, 95% on mice TEM and
84% on macaque TEM. Segmentation of a full rat spinal cord slice is computed
and morphological metrics are extracted and compared against the literature.
AxonDeepSeg is freely available at https://github.com/neuropoly/axondeepsegComment: 14 pages, 7 figure
Potato Classification Using Deep Learning
Abstract: Potatoes are edible tubers, available worldwide and all year long. They are relatively cheap to grow, rich in
nutrients, and they can make a delicious treat. The humble potato has fallen in popularity in recent years, due to the interest
in low-carb foods. However, the fiber, vitamins, minerals, and phytochemicals it provides can help ward off disease and
benefit human health. They are an important staple food in many countries around the world. There are an estimated 200
varieties of potatoes, which can be classified into a number of categories based on the cooked texture and ingredient
functionality. Using a public dataset of 2400 images of potatoes, we trained a deep convolutional neural network to identify
4 types (Red, Red Washed, Sweet, and White).The trained model achieved an accuracy of 99.5% of test set, demonstrating
the feasibility of this approach
A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head
Purpose: To develop a deep learning approach to de-noise optical coherence
tomography (OCT) B-scans of the optic nerve head (ONH).
Methods: Volume scans consisting of 97 horizontal B-scans were acquired
through the center of the ONH using a commercial OCT device (Spectralis) for
both eyes of 20 subjects. For each eye, single-frame (without signal
averaging), and multi-frame (75x signal averaging) volume scans were obtained.
A custom deep learning network was then designed and trained with 2,328 "clean
B-scans" (multi-frame B-scans), and their corresponding "noisy B-scans" (clean
B-scans + gaussian noise) to de-noise the single-frame B-scans. The performance
of the de-noising algorithm was assessed qualitatively, and quantitatively on
1,552 B-scans using the signal to noise ratio (SNR), contrast to noise ratio
(CNR), and mean structural similarity index metrics (MSSIM).
Results: The proposed algorithm successfully denoised unseen single-frame OCT
B-scans. The denoised B-scans were qualitatively similar to their corresponding
multi-frame B-scans, with enhanced visibility of the ONH tissues. The mean SNR
increased from dB (single-frame) to dB
(denoised). For all the ONH tissues, the mean CNR increased from (single-frame) to (denoised). The MSSIM increased from
(single frame) to (denoised) when compared with
the corresponding multi-frame B-scans.
Conclusions: Our deep learning algorithm can denoise a single-frame OCT
B-scan of the ONH in under 20 ms, thus offering a framework to obtain superior
quality OCT B-scans with reduced scanning times and minimal patient discomfort
A General Theory of Equivariant CNNs on Homogeneous Spaces
We present a general theory of Group equivariant Convolutional Neural
Networks (G-CNNs) on homogeneous spaces such as Euclidean space and the sphere.
Feature maps in these networks represent fields on a homogeneous base space,
and layers are equivariant maps between spaces of fields. The theory enables a
systematic classification of all existing G-CNNs in terms of their symmetry
group, base space, and field type. We also consider a fundamental question:
what is the most general kind of equivariant linear map between feature spaces
(fields) of given types? Following Mackey, we show that such maps correspond
one-to-one with convolutions using equivariant kernels, and characterize the
space of such kernels
A Convolutional Neural Network for the Automatic Diagnosis of Collagen VI related Muscular Dystrophies
The development of machine learning systems for the diagnosis of rare
diseases is challenging mainly due the lack of data to study them. Despite this
challenge, this paper proposes a system for the Computer Aided Diagnosis (CAD)
of low-prevalence, congenital muscular dystrophies from confocal microscopy
images. The proposed CAD system relies on a Convolutional Neural Network (CNN)
which performs an independent classification for non-overlapping patches tiling
the input image, and generates an overall decision summarizing the individual
decisions for the patches on the query image. This decision scheme points to
the possibly problematic areas in the input images and provides a global
quantitative evaluation of the state of the patients, which is fundamental for
diagnosis and to monitor the efficiency of therapies.Comment: Submitted for review to Expert Systems With Application
- …