45 research outputs found
Fast Multi-contrast MRI Reconstruction
Abstract. This paper proposes an efficient algorithm to simultaneously reconstruct multiple T1/T2-weighted images of the same anatomical cross section from partially sampled k-space data. The simultaneous re-construction problem is formulated as minimizing a linear combination of three terms corresponding to a least square data fitting, joint total-variation (TV) and group wavelet-sparsity regularization. It is rooted in two observations: 1) the variance of image gradients should be similar for the same spatial position across multiple contrasts; 2) the wavelet coeffi-cients of all images from the same anatomical cross section should have similar sparse modes. To efficiently solve this formulation, we decompose it into group sparsity and joint TV regularization subproblems, respec-tively. Finally, the reconstructed image is obtained from the weighted average of solutions from two subproblems in an iterative framework. We compare the proposed algorithm with previous methods on SRT24 multi-channel Brain Atlas Data. Experiments demonstrate its superior performance for multi-contrast MR image reconstruction.
Groupwise Multimodal Image Registration using Joint Total Variation
In medical imaging it is common practice to acquire a wide range of
modalities (MRI, CT, PET, etc.), to highlight different structures or
pathologies. As patient movement between scans or scanning session is
unavoidable, registration is often an essential step before any subsequent
image analysis. In this paper, we introduce a cost function based on joint
total variation for such multimodal image registration. This cost function has
the advantage of enabling principled, groupwise alignment of multiple images,
whilst being insensitive to strong intensity non-uniformities. We evaluate our
algorithm on rigidly aligning both simulated and real 3D brain scans. This
validation shows robustness to strong intensity non-uniformities and low
registration errors for CT/PET to MRI alignment. Our implementation is publicly
available at https://github.com/brudfors/coregistration-njtv
A Deep Cascade of Convolutional Neural Networks for MR Image Reconstruction
The acquisition of Magnetic Resonance Imaging (MRI) is inherently slow.
Inspired by recent advances in deep learning, we propose a framework for
reconstructing MR images from undersampled data using a deep cascade of
convolutional neural networks to accelerate the data acquisition process. We
show that for Cartesian undersampling of 2D cardiac MR images, the proposed
method outperforms the state-of-the-art compressed sensing approaches, such as
dictionary learning-based MRI (DLMRI) reconstruction, in terms of
reconstruction error, perceptual quality and reconstruction speed for both
3-fold and 6-fold undersampling. Compared to DLMRI, the error produced by the
method proposed is approximately twice as small, allowing to preserve
anatomical structures more faithfully. Using our method, each image can be
reconstructed in 23 ms, which is fast enough to enable real-time applications
Joint Total Variation ESTATICS for Robust Multi-Parameter Mapping
Quantitative magnetic resonance imaging (qMRI) derives tissue-specific
parameters -- such as the apparent transverse relaxation rate R2*, the
longitudinal relaxation rate R1 and the magnetisation transfer saturation --
that can be compared across sites and scanners and carry important information
about the underlying microstructure. The multi-parameter mapping (MPM) protocol
takes advantage of multi-echo acquisitions with variable flip angles to extract
these parameters in a clinically acceptable scan time. In this context,
ESTATICS performs a joint loglinear fit of multiple echo series to extract R2*
and multiple extrapolated intercepts, thereby improving robustness to motion
and decreasing the variance of the estimators. In this paper, we extend this
model in two ways: (1) by introducing a joint total variation (JTV) prior on
the intercepts and decay, and (2) by deriving a nonlinear maximum \emph{a
posteriori} estimate. We evaluated the proposed algorithm by predicting
left-out echoes in a rich single-subject dataset. In this validation, we
outperformed other state-of-the-art methods and additionally showed that the
proposed approach greatly reduces the variance of the estimated maps, without
introducing bias.Comment: 11 pages, 2 figures, 1 table, conference paper, accepted at MICCAI
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