Disentangling the complex association between female genital cutting and HIV among Kenyan women

Female genital cutting (FGC) is a widespread cultural practice in Africa and the Middle East, with a number of potential adverse health consequences for women. It was hypothesised by Kun (1997) that FGC increases the risk of HIV transmission through a number of different mechanisms. Using the 2003 data from the Kenyan Demographic and Health Survey (KDHS), this study investigates the potential association between FGC and HIV. The 2003 KDHS provides a unique opportunity to link the HIV test results with a large number of demographic, social, economic and behavioural characteristics of women, including women’s FGC status. It is hypothesised that FGC increases the risk of HIV infection if HIV/AIDS is present in the community. A multilevel binary logistic regression technique is used to model the HIV status of women, controlling for selected individual characteristics of women and interaction effects. The results demonstrate evidence of a statistically significant association between FGC and HIV, after controlling for the hierarchical structure of the data, potential confounding factors, and interaction effects. The results show that women who had had FGC and a younger or the same age first union partner have higher odds of being HIV positive than women with a younger or same age first union partner but without FGC; whereas women who had had FGC and an older first union partner have lower odds of being HIV positive than women with an older first union partner but without FGC. The findings suggest the behavioural pathway of association between FGC and HIV as well as an underlying complex interplay of bio-behavioural and social variables being important in disentangling the association between FGC and HIV

Does intrauterine crowding affect the force generating capacity and muscle composition of the piglet front limb?

In the pig, intrauterine competition (IUC) greatly affects postnatal traits, such as birth weight, but also locomotor capacities. In a previous study, our group discovered a lower motor performance in piglets with a low birth weight and low vitality (L piglets), compared to piglets with a normal birth weight and normal vitality (N piglets). In order to explain the force deficit causing this reduced motor performance, in a subsequent study, we investigated whether this deficit in L piglets was caused by a lower force generating capacity (FGC) of the extensors of the hind limb and/or a lower number of type II (fast-twitch) fibers in m. vastus lateralis. L piglets had a lower absolute FGC, but surprisingly, a higher relative FGC (to birth weight) in the hind limb, compared to N piglets. In addition, we found no differences in fiber composition of m. vastus lateralis. In the present study, we assessed whether this higher relative FGC is a common feature for front and hind limb locomotor muscles of L piglets. To that end, the physiological cross-sectional area of the main extensor muscles of the front limb was calculated from their volume and fiber length, in order to calculate both the absolute and the relative FGC. By immunohistochemical staining of m. triceps brachii caput longum, the percentage of type II (fast-contracting) fibers could be determined. Similar to the results of the hind limb, we found a smaller absolute FGC, but a larger relative FGC in the front limb of L piglets, compared to N piglets. In addition, m. triceps brachii caput longum did not have a different muscle fiber composition in L and N piglets. As such, we can conclude that IUC affects the locomotor muscles in the front and hind limb in a similar way and that the observed force deficit in L piglets cannot be explained by a different force generating capacity or a lower percentage of type II muscle fibers

Consumer Reaction to the «Flavour Group Concept» to introduce Scab Resistant Apple Varieties into the Market. «Variety-Teams» as a Further Development of the Concept

A tool to ease the market introduction of scab resistant apple varieties in supermarkets, is the so-called «Flavour Group Concept (FGC; Weibel and Grab, 2000) that has been developed by FiBL and «Coop» (second biggest supermarket retailer of Switzerland) already in 1995. The FGC is providing to the buyers additional information on the specific flavour direction of that "unknown" apple cultivar in front of them (mild to sweet; spicy-tart; predominantly tart). In 2002 a consumer behaviour study was undertaken by «IHA/GfK-Switzerland» Institute to evaluate the consumer response to the FGC. The results reveal that 36 % of the persons interviewed at the point of sale considered additional information on the flavour direction of the apple cultivars as «important» and 40 % as «very important». Information on flavour direction was considered as the second important information at the shelf (59 % score), compared to the general presentation of the apples with 78 % score. On basis of these positive results, Coop introduced the FGC also for conventional apples. One year later, also the biggest supermarket retailer of Switzerland «Migros»introduced a FGC for organic and conventional apples. To develop further the FGC, in the year 2002, a consortium of the supermarket chain Coop Switzerland, organic apple growers, retailers and FiBL experts joined together in a so called «Variety Team». There, in contrast to Variety Clubs, the focus is not a particular variety but the active creation and promotion of an attractive assortment of scab resistant apple varieties in a well co-ordinated and thus for growers and retailers most efficient way. Investments and risks are evenly shared between the Team Partners. The first cultivar promoted is «Ecolette»

Analytic Properties and Covariance Functions of a New Class of Generalized Gibbs Random Fields

Spartan Spatial Random Fields (SSRFs) are generalized Gibbs random fields, equipped with a coarse-graining kernel that acts as a low-pass filter for the fluctuations. SSRFs are defined by means of physically motivated spatial interactions and a small set of free parameters (interaction couplings). This paper focuses on the FGC-SSRF model, which is defined on the Euclidean space $\mathbb{R}^{d}$ by means of interactions proportional to the squares of the field realizations, as well as their gradient and curvature. The permissibility criteria of FGC-SSRFs are extended by considering the impact of a finite-bandwidth kernel. It is proved that the FGC-SSRFs are almost surely differentiable in the case of finite bandwidth. Asymptotic explicit expressions for the Spartan covariance function are derived for $d=1$ and $d=3$; both known and new covariance functions are obtained depending on the value of the FGC-SSRF shape parameter. Nonlinear dependence of the covariance integral scale on the FGC-SSRF characteristic length is established, and it is shown that the relation becomes linear asymptotically. The results presented in this paper are useful in random field parameter inference, as well as in spatial interpolation of irregularly-spaced samples.Comment: 24 pages; 4 figures Submitted for publication to IEEE Transactions on Information Theor

Developing Normative Consensus: How the International Scene Reshapes the Debate over Internal and External Criticism

Can we ever justly critique the norms and practices of another culture? When activists or policy-makers decide that one culture’s traditional practice is harmful and needs to be eradicated, does it matter whether they are members of that culture? Given the history of imperialism, many argue that any critique of another culture’s practices must be internal. Others argue that we can appeal to a universal standard of human well-being to determine whether or not a particular practice is legitimate or whether it should be eradicated. In this paper, I use the FGC eradication campaigns of the 1980s to show that the internal/external divide is complicated by the inter-connectedness of these debates on the international level. As the line blurs between internal and external criticism and interventions, new questions emerge about the representativeness of global institutions

Millisecond pulsars and the gamma-ray excess in Andromeda

The Fermi Gamma-Ray Space Telescope has provided evidence for diffuse gamma-ray emission in the central parts of the Milky Way and the Andromeda galaxy. This excess has been interpreted either as dark matter annihilation emission or as emission from thousands of millisecond pulsars (MSPs). We have recently shown that old massive globular clusters may move towards the center of the Galaxy by dynamical friction and carry within them enough MSPs to account for the observed gamma-ray excess. In this paper we revisit the MSP scenario for the Andromeda galaxy, by modeling the formation and disruption of its globular cluster system. We find that our model predicts gamma-ray emission $\sim 2-3$ times larger than for the Milky Way, but still nearly an order of magnitude smaller than the observed Fermi excess in the Andromeda. Our MSP model can reproduce the observed excess only by assuming $\sim 8$ times larger number of old clusters than inferred from galaxy scaling relations. To explain the observations we require either that Andromeda deviates significantly from the scaling relations, or that a large part of its high-energy emission comes from additional sources.Comment: 5 pages, 2 figures, 1 Table, accepted by ApJ Let