Pairwise Quantization

We consider the task of lossy compression of high-dimensional vectors through quantization. We propose the approach that learns quantization parameters by minimizing the distortion of scalar products and squared distances between pairs of points. This is in contrast to previous works that obtain these parameters through the minimization of the reconstruction error of individual points. The proposed approach proceeds by finding a linear transformation of the data that effectively reduces the minimization of the pairwise distortions to the minimization of individual reconstruction errors. After such transformation, any of the previously-proposed quantization approaches can be used. Despite the simplicity of this transformation, the experiments demonstrate that it achieves considerable reduction of the pairwise distortions compared to applying quantization directly to the untransformed data

Rapid three-dimensional multiparametric MRI with quantitative transient-state imaging

Novel methods for quantitative, transient-state multiparametric imaging are increasingly being demonstrated for assessment of disease and treatment efficacy. Here, we build on these by assessing the most common Non-Cartesian readout trajectories (2D/3D radials and spirals), demonstrating efficient anti-aliasing with a k-space view-sharing technique, and proposing novel methods for parameter inference with neural networks that incorporate the estimation of proton density. Our results show good agreement with gold standard and phantom references for all readout trajectories at 1.5T and 3T. Parameters inferred with the neural network were within 6.58% difference from the parameters inferred with a high-resolution dictionary. Concordance correlation coefficients were above 0.92 and the normalized root mean squared error ranged between 4.2% - 12.7% with respect to gold-standard phantom references for T1 and T2. In vivo acquisitions demonstrate sub-millimetric isotropic resolution in under five minutes with reconstruction and inference times < 7 minutes. Our 3D quantitative transient-state imaging approach could enable high-resolution multiparametric tissue quantification within clinically acceptable acquisition and reconstruction times.Comment: 43 pages, 12 Figures, 5 Table