3,952,189 research outputs found

    Cost‐effectiveness analysis of computer‐based assessment

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    The need for more cost‐effective and pedagogically acceptable combinations of teaching and learning methods to sustain increasing student numbers means that the use of innovative methods, using technology, is accelerating. There is an expectation that economies of scale might provide greater cost‐effectiveness whilst also enhancing student learning. The difficulties and complexities of these expectations are considered in this paper, which explores the challenges faced by those wishing to evaluate the cost‐effectiveness of computer‐based assessment (CBA). The paper outlines the outcomes of a survey which attempted to gather information about the costs and benefits of CBA

    Molecular Analysis and Effectiveness Assay of AV1 Gene in Transgenic Tobacco for Resistance to Begomovirus

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    Genetic transformationof tobacco plant using AV1 gene was conducted atthe previously experiment and generated transgenic tobaccoplants positively carrying the selectable marker nptII gene.The objectives of this experiment were to (1) analyze thepresence of Begomovirus AV1 gene in T0 generation putativetransgenic tobacco plants using PCR technique with specificprimers and its correlation with resistance phenotype, (2)analyze the integration and copy number of the transgene inT0 generation putative transgenic tobacco plants and itscorrelation with resistance response, (3) screen the T0generation putative transgenic tobacco plants with the targetvirus infection and to detect the presence of the virus in thetransgenic plant tissue using universal primers. PCRdetection of AV1 gene in tobacco transgenic was conductedby using specific primer for Begomovirus AV1 gene.Meanwhile, Southern Blot analysis was conducted by usingthe AV1 gene probe. The effectiveness of AV1 gene intobacco transgenic was tested by inoculation of target virususing whiteflies vector. Result of the experiments showedthat there was a positive correlation between the presenceof the AV1 transgene in T0 generation putative transgenictobacco plants and the resistant phenotype. Transgenicplants with a single copy integration of the transgeneexhibited more resistant than the multiple copy one. andnon transgenic plant. The resistance as a result of AV1 geneexpression was indicated with no symptom in T0 generationtransgenic tobacco plants and the accumulation of the virusin the transgenic plants tissue. Northern and Westernhybridization analysis need to be perfomed for investigatingthe presence of mRNA or protein accumulation so that theresistance mechanism of the AV1 gene could be explainedmore detail

    A Bayesian approach to stochastic cost-effectiveness analysis

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    The aim of this paper is to discuss the use of Bayesian methods in cost-effectiveness analysis (CEA) and the common ground between Bayesian and traditional frequentist approaches. A further aim is to explore the use of the net benefit statistic and its advantages over the incremental cost-effectiveness ratio (ICER) statistic. In particular, the use of cost-effectiveness acceptability curves is examined as a device for presenting the implications of uncertainty in a CEA to decision makers. Although it is argued that the interpretation of such curves as the probability that an intervention is cost-effective given the data requires a Bayesian approach, this should generate no misgivings for the frequentist. Furthermore, cost-effectiveness acceptability curves estimated using the net benefit statistic are exactly equivalent to those estimated from an appropriate analysis of ICERs on the cost-effectiveness plane. The principles examined in this paper are illustrated by application to the cost-effectiveness of blood pressure control in the U.K. Prospective Diabetes Study (UKPDS 40). Due to a lack of good-quality prior information on the cost and effectiveness of blood pressure control in diabetes, a Bayesian analysis assuming an uninformative prior is argued to be most appropriate. This generates exactly the same cost-effectiveness results as a standard frequentist analysis

    Using cost effectiveness analysis; a beginners guide

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    Objective ‐ This report seeks to describe the key elements of cost effectiveness analysis (CEA) and to demonstrate how such analysis may be used in the library environment. Methods ‐ The paper uses a step‐by‐step approach to walk the non‐economist reader through the basics of conducting a cost effectiveness study. It provides an outline of the key elements of CEA using examples from the library sector, and it presents a case study of a CEA in a hospital library. The case study compares two library services, mediated searching and information skills training, to illustrate the application of CEA and to highlight some of its limitations. Results ‐ CEA is a comparative analysis tool. Its key elements include a study question regarding a particular process or procedure that identifies both costs and effectiveness; a justification of the study’s perspective; evidence of effectiveness; comprehensive identification of all relevant costs, and appropriate measurement of costs and effectiveness. Conclusions ‐ CEA enables comparison of services or interventions regarding particular processes or procedures in terms of their costs, and it measures their effectiveness. The results can be used to aid decision‐making about service provision

    Analysis of the Effectiveness of Supplier Selection That Affect to Business' Productivity (Case Study: Ayam Goreng Nelongso)

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    The purpose of this journal is to identify the effectiveness of the supply chain from the point of supplier selection. This study is important because some businesses in Indonesia are not interest how to choose and determine the quantity of suppliers that can support the productivity of the company. This study uses Ayam Goreng Nelongso as a case study. Data analysis that obtained as the basic of writing this journal is through interviews with related parties. The theory that applied in this journal are based on the material that has been submitted by the author's lecturer to find the best strategy for choosing supplier. Keywords: Supplier Selection, Business' Productivity, Ayam Goreng Nelongso

    Cost-Effectiveness Analysis Terapi Antibiotik Seftriakson Dan Sefotaksim Pada Pasien Tifoid Di RSUD Dr. M.M Dunda Limboto

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    Tifoid merupakan penyakit infeksi yang disebabkan oleh bakteri Salmonella typhi dan telah banyak menginfeksi masyarakat baik di perkotaan maupun pedesaan. Dengan adanya fenomena multidrug resistance Salmonella typhi maka pemilihan terapi antibiotik yang efektif pada tifoid menjadi faktor yang harus diperhatikan selain kendala biaya. Penelitian ini bertujuan untuk mengetahui efektivitas biaya pada terapi dua antibiotik yaitu seftriakson dan sefotaksim yang digunakan dalam pengobatan demam tifoid di RSUD DR. M.M Dunda Limboto. Penelitian ini dilakukan dengan menggunakan metode survei analitik dengan desain cross sectional. Penelitian ini menggunakan data sekunder pasien demam tifoid periode Januari-Desember 2014. Data yang diambil meliputi, data demografi, lama rawat inap, dan data keuangan pasien. Hasil penelitian menunjukkan bahwa kelompok terapi antibiotik seftriakson lebih cost effective yaitu dengan biaya Rp 3.650.091 dengan lama rawat inap 2,8 hari dibandingkan dengan kelompok terapi antibiotik sefotaksim dengan biaya lebih besar yaitu Rp 4.036.015 dengan lama rawat inap 3,7 hari

    Effectiveness Analysis of “Shangri-la Academy Program” Towards Employees' Working Motivation at Shangri-la Hotel Surabaya

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    This research has taken place at Shangri-La Hotel Surabaya, an International management hotel. The population of research is 573 respondents. The purpose of this research is to understand the effectiveness of Shangri-La Academy Program and the employees' working motivation at Shangri-La Hotel Surabaya. The analysis technique uses descriptive quantitative analysis. The result of research showed that there is a dependency between Shangri-La Academy Program and employees' working motivation Shangri-La Hotel Surabaya

    Effectiveness of poverty reduction in the EU: A descriptive analysis

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    The European Union coordinates and encourages Member State actions to combat poverty, and to reform their social protection systems on the basis of policy exchanges and mutual learning (‘best practices’). Some EU countries are more effective in poverty reduction than others. What can explain these variations in effectiveness? This paper analyses the effectiveness of welfare state policies and especially social transfers in EU-countries in alleviating poverty. To indicate whether European economic integration may have had any impact on poverty reduction, we also include several non-EU15 countries as a benchmark into our analysis. We analyze on a cross-country basis the relationship between poverty rates and social effort, as measured by social expenditure ratios. We also correct these expenditure ratios for the impact of the tax system and for private social arrangements, using OECD methodology. Next, we compare poverty rates at the levels of market and disposable incomes, that is before and after transfers, in order to analyze the effect of tax and transfer policies in reducing poverty, i.e. to determine the target efficiency of social transfers. We perform several tests with the most recent data (LIS, OECD SOCX, and Eurostat: ECHP/EU-SILC). Our results are less clear cut than earlier findings. We still find a quite strong negative relationship between the level of social expenditure and poverty among OECD countries. However, for EU-countries this relationship is weaker and there are substantial differences within the EU15. After correcting for the impact of taxes and for private social arrangements, the linkage between social effort and poverty levels becomes even weaker. Also, we do not find a strong relationship between levels of social spending and antipoverty effects of social transfers and taxes. At the program level, family programs and child support alleviate poverty to a large extent

    (Correcting) misdiagnoses of asthma: A cost effectiveness analysis

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Background: The prevalence of physician-diagnosed-asthma has risen over the past three decades and misdiagnosis of asthma is potentially common. Objective: to determine whether a secondary-screening-program to establish a correct diagnosis of asthma in those who report a physician diagnosis of asthma is cost effective.Method: Randomly selected physician-diagnosed-asthmatic subjects from 8 Canadian cities were studied with an extensive diagnostic algorithm to rule-in, or rule-out, a correct diagnosis of asthma. Subjects in whom the diagnosis of asthma was excluded were followed up for 6-months and data on asthma medications and heath care utilization was obtained. Economic analysis was performed to estimate the incremental lifetime costs associated with secondary screening of previously diagnosed asthmatic subjects. Analysis was from the perspective of the Canadian healthcare system and is reported in Canadian dollars.Results: Of 540 randomly selected patients with physician diagnosed asthma 150 (28%; 95%CI 19-37%) did not have asthma when objectively studied. 71% of these misdiagnosed patients were on some asthma medications. Incorporating the incremental cost of secondary-screening for the diagnosis of asthma, we found that the average cost savings per 100 individuals screened was 35,141(9535,141 (95%CI 4,588-$69,278).Conclusion: Cost savings primarily resulted from lifetime costs of medication use averted in those who had been misdiagnosed.This work was funded by the Canadian Institute of Health Research, Canada and the University Of Ottawa Division Of Respiratory Medicine
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