1,511 research outputs found

    Phage inducible islands in the gram-positive cocci

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    The SaPIs are a cohesive subfamily of extremely common phage-inducible chromosomal islands (PICIs) that reside quiescently at specific att sites in the staphylococcal chromosome and are induced by helper phages to excise and replicate. They are usually packaged in small capsids composed of phage virion proteins, giving rise to very high transfer frequencies, which they enhance by interfering with helper phage reproduction. As the SaPIs represent a highly successful biological strategy, with many natural Staphylococcus aureus strains containing two or more, we assumed that similar elements would be widespread in the Gram-positive cocci. On the basis of resemblance to the paradigmatic SaPI genome, we have readily identified large cohesive families of similar elements in the lactococci and pneumococci/streptococci plus a few such elements in Enterococcus faecalis. Based on extensive ortholog analyses, we found that the PICI elements in the four different genera all represent distinct but parallel lineages, suggesting that they represent convergent evolution towards a highly successful lifestyle. We have characterized in depth the enterococcal element, EfCIV583, and have shown that it very closely resembles the SaPIs in functionality as well as in genome organization, setting the stage for expansion of the study of elements of this type. In summary, our findings greatly broaden the PICI family to include elements from at least three genera of cocci

    Graded-index fiber collimator enhanced extrinsic Fabry-Perot interferometer

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    In this thesis, we studied a fringe visibility enhanced extrinsic Fabry-Perot interferometer (EFPI) by fusion splicing a quarter-pitch graded-index fiber (GIF) fiber to the lead-in single-mode fiber (SMF). The performance of the GIF collimator is theoretically analyzed using a ray matrix model and experimentally verified through beam divergence angle measurements. The fringe visibility of the GIF-collimated EFPI is measured as a function of the cavity length and compared with that of a regular SMF-EFPI. At the cavity length of 500µm, the fringe visibility of the GIF-EFPI is 0.8 while that of the SMF-EFPI is only 0.2. The visibility enhanced GIF-EFPI provides better a signal-to-noise (SNR) for applications where a large dynamic range is desired --Abstract, page iii

    The Breathing Mode in Extended Skyrme Model

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    We study an extended Skyrme model which includes fourth and sixth-order terms. We explore some static properties like the Δ\Delta-nucleon mass splitting and investigate the Skyrmion breathing mode in the framework of the linear response theory. We find that the monopole response function has a pronounced peak located at \sim 400 MeV, which we identify to the Roper resonance N(1440)N(1440). As compared to the standard one, the extended Skyrme model provides a more accurate description of baryon properties.Comment: 12 pages of plain Latex and 3 figures (available from the authors), preprint IPNO/TH 93-0

    Review: optical fiber sensors for civil engineering applications

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    Optical fiber sensor (OFS) technologies have developed rapidly over the last few decades, and various types of OFS have found practical applications in the field of civil engineering. In this paper, which is resulting from the work of the RILEM technical committee “Optical fiber sensors for civil engineering applications”, different kinds of sensing techniques, including change of light intensity, interferometry, fiber Bragg grating, adsorption measurement and distributed sensing, are briefly reviewed to introduce the basic sensing principles. Then, the applications of OFS in highway structures, building structures, geotechnical structures, pipelines as well as cables monitoring are described, with focus on sensor design, installation technique and sensor performance. It is believed that the State-of-the-Art review is helpful to engineers considering the use of OFS in their projects, and can facilitate the wider application of OFS technologies in construction industry

    Reparametrising the Skyrme Model using the Lithium-6 Nucleus

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    The minimal energy B=6 solution of the Skyrme model is a static soliton with D4dD_{4d} symmetry. The symmetries of the solution imply that the quantum numbers of the ground state are the same as those of the Lithium-6 nucleus. This identification is considered further by obtaining expressions for the mean charge radius and quadrupole moment, dependent only on the Skyrme model parameters ee (a dimensionless constant) and FπF_\pi (the pion decay constant). The optimal values of these parameters have often been deliberated upon, and we propose, for B>2B>2, changing them from those which are most commonly accepted. We obtain specific values for these parameters for B=6, by matching with properties of the Lithium-6 nucleus. We find further support for the new values by reconsidering the α\alpha-particle and deuteron as quantized B=4 and B=2 Skyrmions.Comment: 18 page
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