Muscle force is determined also by muscle relative position: isolated effects

Effects on force of changes of the position of extensor digitorum longus muscle (EDL) relative to surrounding tissues were investigated in rat. Connective tissue at the muscle bellies of tibialis anterior (TA), extensor hallucis longus (EHL) and EDL was left intact, to allow myofascial force transmission. The position of EDL muscle was altered, without changing EDL muscle–tendon complex length, and force exerted at proximal and distal tendons of EDL as well as summed force exerted at the distal tendons of TA and EHL muscles (TA+EHL) were measured. Proximal and distal EDL forces as well as distal TA+EHL force changed significantly on repositioning EDL muscle.\ud \ud These muscle position–force characteristics were assessed at two EDL lengths and two TA+EHL lengths. It was shown that changes of muscle force with length changes of a muscle is the result of the length changes per se, as well as of changes of relative position of parts of the muscle. It is concluded that in addition to length, muscle position relative to its surroundings co-determines isometric muscle force.\ud \ud Keywords: Intermuscular and extramuscular connective tissue; Myofascial force transmission; Rat m. extensor digitorum longus (EDL); Sarcomere length; Muscle relative positio

Coulometry and Calorimetry of Electric Double Layer Formation in Porous Electrodes

Coulometric measurements on salt-water-immersed nanoporous carbon electrodes reveal, at a fixed voltage, a charge decrease with increasing temperature. During far-out-of-equilibrium charging of these electrodes, calorimetry indicates the production of both irreversible Joule heat and reversible heat, the latter being associated with entropy changes during electric double layer (EDL) formation in the nanopores. These measurements grant experimental access --for the first time-- to the entropic contribution of the grand potential; for our electrodes, this amounts to roughly 25% of the total grand potential energy cost of EDL formation at large applied potentials, in contrast with point-charge model calculations that predict 100%. The coulometric and calorimetric experiments show a consistent picture of the role of heat and temperature in EDL formation and provide hitherto unused information to test against EDL models.Comment: 11 pages, 10 figure

Inside the EDL: Populist politi

The English Defence League (EDL) is the biggest populist street movement in a generation. Yet the make-up of the group and what its members believe remain a mystery because it has no formal joining procedures or membership list and much of its activity takes place online. While leaders of the EDL claim they are a pluralistic, liberal movement that is fighting Islamic extremism, chants heard at demonstrations and the vitriol frequently posted on the EDL’s chat forums suggest otherwise. It is in this context that we have undertaken the first ever large-scale empirical study of the EDL, which comprises responses from 1,295 sympathisers and supporters, and includes data on their demographics, involvement in EDL activity, political attitudes and social views. The results show that, although the EDL is usually understood as an anti-Islamic or anti-Islamist demonstrating group, the reality is more complex. Supporters are characterised by intense pessimism about the UK's future, worries about immigration and joblessness. This is often mixed with a proactive pride in Britain, British history and British values, which they see as being under attack from Islam. Although their demonstrations have often involved violence and racist chants, many members are democrats who are committed to peaceful protest and other forms of activism. The collection of large amounts of data from social media presents new opportunities for social research to understand the relationship between off- and online activity. As more movements combine – and blur – virtual and real protest, these questions will become increasingly urgent and important. These surveys, collected through Facebook using a new methodology, offer new ways forward in exploring this challenge

Comparison of the Knowledge in Core Policies of Essential Drug List Among Medical Practitioners and Medical Students in Galle, Sri Lanka

Selection of the best and safest medicine should be one of the national economic policies in a country for good health care services. Introduction of detailed module in rational use of medicine (RUM) to pharmacology syllabus needed prior analysis of the existing knowledge among health care workers. Therefore we assessed the knowledge and attitudes of essential drug list (EDL) on medical practitioners (MPs) and medical students (MSs). Forty two MPs and 120 MSs from hospital and Faculty of Medicine were given a pretested structured questionnaire related to core policies of EDL, contents, criteria for selection and time frame for revision in RUM. Our study showed that only 29% of MPs were confident about their knowledge in EDL and 17% of them had marked it as don’t know. Study was expanded for quantitative analysis of the knowledge on the core policies of EDL on them. Knowledge on contents, criteria for selection and the time frame for revision of EDL were 63%, 83% and 17% in MPs. Of MSs, 87% had sound knowledge in core contents, 32% in criteria for selection and only 50% of MSs were aware about the correct time frame of revision of EDL. Knowledge in contents of EDL was higher in MSs (87%) than MPs(63&). MPs were not aware about EDL preparing criteria such as inclusion of generic names, common ailment, majority ailments of the people (59%, 56% and 56% respectively). In contrast, MSs had > 93% of the knowledge in all three areas. However MSs had poorer knowledge (32%) in criteria for selection of EDL than MPs (83%). Knowledge in time frame for revision of EDL was 17% in MPs and 50% in MSs. We found that MPs in the service were not convinced about their knowledge in EDL. Deficiency was significant in the core contents of the EDL preparation. Therefore we suggest that MPs need repetitive in-service training programme for practicing of RUM in the national health facilities. We need to reiterative programme in the core curriculum regarding the criteria for EDL selection. Though MSs had good knowledge in content of EDL, they are poor in criteria for selection and time frame for revision

AC impedance spectroscopy characteristics of chloride-exposed cement pastes

In this paper, the characteristics of AC impedance spectroscopy of cement paste immersed in chloride solution were measured and analyzed with a proposed equivalent circuit model. The elements in the proposed equivalent circuit, including the resistance of interface between electrode and specimens, resistance of continuous and discontinuous pore, capacitance of solid phase and electrical double layer (EDL) were discussed. The results showed that the resistance of interface between electrode and testing specimen was much lower than that of cement paste. With the increase of chloride concentration in the soaking solution, the resistance of continuous gradually decreased due to the higher conductivity of chloride solution. Stripped out the impacts of concentration of pore solution on resistance of pores, the resistance of continuous pore increased firstly due to the decrease of continuous pore volume from the formation of Friedel's salt. However, the resistance of discontinuous pores gradually decreased with the increase of soaking solution concentration due to the transformation of continuous pores to discontinuous pores. The reaction between chloride ions and hydration products and formation of Friedel's salt decreased the porosity of cement pastes and led to higher capacitance of solid phase. Based on an idealized two-plate capacitor model for EDL, the thickness of EDL was calculated from the measured capacitance. The decrease of EDL thickness with chloride concentration in soaking solution was in agreement with the results of chloride contents in EDL obtained from pore solution expression test. (C) 2019 Elsevier Ltd. All rights reserved

Dense ionic fluids confined in planar capacitors: in- and out-of-plane structure from classical density functional theory

The ongoing scientific interest in the properties and structure of electric double layers (EDLs) stems from their pivotal role in (super)capacitive energy storage, energy harvesting, and water treatment technologies. Classical density functional theory (DFT) is a promising framework for the study of the in- and out-of-plane structural properties of double layers. Supported by molecular dynamics simulations, we demonstrate the adequate performance of DFT for analyzing charge layering in the EDL perpendicular to the electrodes. We discuss charge storage and capacitance of the EDL and the impact of screening due to dielectric solvents. We further calculate, for the first time, the in-plane structure of the EDL within the framework of DFT. While our out-of-plane results already hint at structural in-plane transitions inside the EDL, which have been observed recently in simulations and experiments, our DFT approach performs poorly in predicting in-plane structure in comparison to simulations. However, our findings isolate fundamental issues in the theoretical description of the EDL within the primitive model and point towards limitations in the performance of DFT in describing the out-of-plane structure of the EDL at high concentrations and potentials

Steric-effect-induced enhancement of electrical-double-layer overlapping phenomena\ud

In this paper, we demonstrate that nontrivial interactions between steric effect and electrical-double-layer (EDL) overlap phenomena may augment the effective extent of EDL overlap in narrow fluidic confinements to a significant extent by virtue of rendering the channel centerline potential tending to the ζ potential in a limiting sense as the steric effect progressively intensifies. Such a behavior may result in a virtually uniform (undiminished) magnitude of the EDL potential across the entire channel height and may cause lowering of the total charge within the EDL.\ud \u