10,100 research outputs found
An Unsupervised Learning Model for Deformable Medical Image Registration
We present a fast learning-based algorithm for deformable, pairwise 3D
medical image registration. Current registration methods optimize an objective
function independently for each pair of images, which can be time-consuming for
large data. We define registration as a parametric function, and optimize its
parameters given a set of images from a collection of interest. Given a new
pair of scans, we can quickly compute a registration field by directly
evaluating the function using the learned parameters. We model this function
using a convolutional neural network (CNN), and use a spatial transform layer
to reconstruct one image from another while imposing smoothness constraints on
the registration field. The proposed method does not require supervised
information such as ground truth registration fields or anatomical landmarks.
We demonstrate registration accuracy comparable to state-of-the-art 3D image
registration, while operating orders of magnitude faster in practice. Our
method promises to significantly speed up medical image analysis and processing
pipelines, while facilitating novel directions in learning-based registration
and its applications. Our code is available at
https://github.com/balakg/voxelmorph .Comment: 9 pages, in CVPR 201
Learning Deep Similarity Metric for 3D MR-TRUS Registration
Purpose: The fusion of transrectal ultrasound (TRUS) and magnetic resonance
(MR) images for guiding targeted prostate biopsy has significantly improved the
biopsy yield of aggressive cancers. A key component of MR-TRUS fusion is image
registration. However, it is very challenging to obtain a robust automatic
MR-TRUS registration due to the large appearance difference between the two
imaging modalities. The work presented in this paper aims to tackle this
problem by addressing two challenges: (i) the definition of a suitable
similarity metric and (ii) the determination of a suitable optimization
strategy.
Methods: This work proposes the use of a deep convolutional neural network to
learn a similarity metric for MR-TRUS registration. We also use a composite
optimization strategy that explores the solution space in order to search for a
suitable initialization for the second-order optimization of the learned
metric. Further, a multi-pass approach is used in order to smooth the metric
for optimization.
Results: The learned similarity metric outperforms the classical mutual
information and also the state-of-the-art MIND feature based methods. The
results indicate that the overall registration framework has a large capture
range. The proposed deep similarity metric based approach obtained a mean TRE
of 3.86mm (with an initial TRE of 16mm) for this challenging problem.
Conclusion: A similarity metric that is learned using a deep neural network
can be used to assess the quality of any given image registration and can be
used in conjunction with the aforementioned optimization framework to perform
automatic registration that is robust to poor initialization.Comment: To appear on IJCAR
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