Learning to detect chest radiographs containing lung nodules using visual attention networks

Machine learning approaches hold great potential for the automated detection of lung nodules in chest radiographs, but training the algorithms requires vary large amounts of manually annotated images, which are difficult to obtain. Weak labels indicating whether a radiograph is likely to contain pulmonary nodules are typically easier to obtain at scale by parsing historical free-text radiological reports associated to the radiographs. Using a repositotory of over 700,000 chest radiographs, in this study we demonstrate that promising nodule detection performance can be achieved using weak labels through convolutional neural networks for radiograph classification. We propose two network architectures for the classification of images likely to contain pulmonary nodules using both weak labels and manually-delineated bounding boxes, when these are available. Annotated nodules are used at training time to deliver a visual attention mechanism informing the model about its localisation performance. The first architecture extracts saliency maps from high-level convolutional layers and compares the estimated position of a nodule against the ground truth, when this is available. A corresponding localisation error is then back-propagated along with the softmax classification error. The second approach consists of a recurrent attention model that learns to observe a short sequence of smaller image portions through reinforcement learning. When a nodule annotation is available at training time, the reward function is modified accordingly so that exploring portions of the radiographs away from a nodule incurs a larger penalty. Our empirical results demonstrate the potential advantages of these architectures in comparison to competing methodologies

Deep Unsupervised Saliency Detection: A Multiple Noisy Labeling Perspective

The success of current deep saliency detection methods heavily depends on the availability of large-scale supervision in the form of per-pixel labeling. Such supervision, while labor-intensive and not always possible, tends to hinder the generalization ability of the learned models. By contrast, traditional handcrafted features based unsupervised saliency detection methods, even though have been surpassed by the deep supervised methods, are generally dataset-independent and could be applied in the wild. This raises a natural question that "Is it possible to learn saliency maps without using labeled data while improving the generalization ability?". To this end, we present a novel perspective to unsupervised saliency detection through learning from multiple noisy labeling generated by "weak" and "noisy" unsupervised handcrafted saliency methods. Our end-to-end deep learning framework for unsupervised saliency detection consists of a latent saliency prediction module and a noise modeling module that work collaboratively and are optimized jointly. Explicit noise modeling enables us to deal with noisy saliency maps in a probabilistic way. Extensive experimental results on various benchmarking datasets show that our model not only outperforms all the unsupervised saliency methods with a large margin but also achieves comparable performance with the recent state-of-the-art supervised deep saliency methods.Comment: Accepted by IEEE/CVF CVPR 2018 as Spotligh