99,383 research outputs found
Irritable digestive tract
This new nosologic entity known as "Nasio irritable digestive tract", is defined as the reversible, functional neuromyosecreory trouble of the whole or a segment of the digestive tract, that alternates with periods of health with an irregular and long evolution, influenced particularly by psychical factors, and that develops in neurovegetative distony constitutions.</p
Utilization of Channels Digestion Golden Snail (Pomacea Canaliculata) as Lytic Enzyme and Application on Yeast Pichia Manshurica DUCC-Y15
Mollusks were one of invertebrate animals that have not been studied and used in in the field of enzyme. One type of mollusk that has not been exploited significantly is golden snail (Pomacea canaliculata), especially in the digestive tract for the production of lytic enzymes. Lytic enzymes can be used as a microbial cell wall-breaking agents that will produce protoplasts, besides that this enzyme plays an important role in protoplast isolation technique producing good and healthy protoplasts. Protoplasts derived from the yeast Pichia manshurica DUCC-Y15is capable of producing the inulinase enzyme. The aim of this study was to use the digestive tract golden snail (Pomacea canaliculata) as lytic enzymes and to determine the amount of the released protoplasts at a concentration level of lytic enzymes different from the digestive tract golden snail (Pomacea canaliculata). Lytic enzyme concentrations used in this study was 75% (E3) and 100% (E4). The results showed that the digestive tract golden snail (Pomacea canaliculata) can produce lytic enzymes, the higher the concentration of lytic enzymes digestive tract golden snail given, then the higher the protoplasts were released. At a concentration of 75% lytic enzyme (E3) liberate protoplasts of 6.7 x 1017 (33.4%) and 100% (E4) of 9.9 x 1017 (45%)
Covalent bonding of polycations to small polymeric particles
Process produces small spherical polymeric particles which have polycations bound to them. In emulsion form, particles present large positively charged surface which is available to absorb polyanions. This properly can be used in removing heparin from blood or bile acids from the digestive tract. Other anions, such as DNA and RNA, can also be removed from aqueous solutions
Role of Digestive Tract Hormone in Functional Dyspepsia
Dyspepsia is a complaint commonly found in daily practice. Functional dyspepsia is considered if the organic cause of dyspepsia is not found. The pathophysiology of functional dyspepsia has not been fully understood.However there are three main pathophysiology, which are: motility disturbance, non-motility disturbance, and psychosocial factor. Several digestive tract hormones are ghrelin, motilin, cholecystokinin (CCK), peptide YY (PYY), somatostatin, glucagon-like-peptide 1 (GLP), are thought to play role in the pathophysiology of functional dyspepsia, particularly in the regulation of digestive tract motility. Currently, a new paradigm in digestive tract disturbance treatment is developing, such as motilin receptor agonist therapy (for example mitemcinal) and ghrelin receptor agonist therapy, which is used as one of the new modalities in treatment of dyspepsia
Composition of the Adult Digestive Tract Bacterial Microbiome Based on Seven Mouth Surfaces, Tonsils, Throat and Stool Samples
Background: To understand the relationship between our bacterial microbiome and health, it is essential to define the microbiome in the absence of disease. The digestive tract includes diverse habitats and hosts the human body's greatest bacterial density. We describe the bacterial community composition of ten digestive tract sites from more than 200 normal adults enrolled in the Human Microbiome Project, and metagenomically determined metabolic potentials of four representative sites. Results: The microbiota of these diverse habitats formed four groups based on similar community compositions: buccal mucosa, keratinized gingiva, hard palate; saliva, tongue, tonsils, throat; sub- and supra-gingival plaques; and stool. Phyla initially identified from environmental samples were detected throughout this population, primarily TM7, SR1, and Synergistetes. Genera with pathogenic members were well-represented among this disease-free cohort. Tooth-associated communities were distinct, but not entirely dissimilar, from other oral surfaces. The Porphyromonadaceae, Veillonellaceae and Lachnospiraceae families were common to all sites, but the distributions of their genera varied significantly. Most metabolic processes were distributed widely throughout the digestive tract microbiota, with variations in metagenomic abundance between body habitats. These included shifts in sugar transporter types between the supragingival plaque, other oral surfaces, and stool; hydrogen and hydrogen sulfide production were also differentially distributed. Conclusions: The microbiomes of ten digestive tract sites separated into four types based on composition. A core set of metabolic pathways was present across these diverse digestive tract habitats. These data provide a critical baseline for future studies investigating local and systemic diseases affecting human health
Hyaluronic acid: perspectives in upper aero-digestive tract. A systematic review
Background: To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the mucosa of the upper aerodigestive tract (UADT). The use of topical drugs, which are able to reduce mucosal inflammation and to improve healing tissues, can represent a relevant therapeutic advance. Topical sodium hyaluronate (SH) has recently been recognized as adjuvant treatment in the chronic inflammatory disease of the UADT. Aims: The aim of our work was to review the published literature regarding all the potential therapeutic effects of SH in the chronic inflammatory disease of UADT. Methods: Relevant published studies were searched in Pubmed, Google Scholar, Ovid using ("sodium hyaluronate" and "upper airways") or Medical Subject Headings. Results: At the end of our selection process, sixteen publications have been included. Six of them in the post-operative period of nasal-sinus surgery, 2 of them in pediatric patients affected by recurrent upper respiratory tract infections, 4 of them in reducing symptoms and preventing exacerbations of chronic upper airways in adult population, 4 of them in patients with chronic inflammatory disease of UADT, including gastro-esophageal reflux disease (GERD). Conclusions: Topical administration of SH plays a pivotkey role in the postoperative phase of patients undergoing FESS and nasal surgery, and positive results are generally observed in all the patients suffering from UADT chronic inflammatory disease
Management of Upper Aerodigestive Tract Bleeding in Patients on ECMO.
Introduction: Bleeding complications on Extracorporeal Membrane Oxygenation (ECMO) are often encountered. In a review of our own series, it was found that upper aero digestive tract bleeding was common and management was often difficult. We propose an algorithm to help manage upper aero digestive tract bleeding in the anticoagulated, ECMO patient. Hypothesis: Once an ECMO patient fails conservative management for upper aero digestive bleeding, more aggressive measures will prove successful, which will provide benefit to the patient. Methods: A retrospective chart review was performed of the patients who underwent venovenous or veno-arterial ECMO at our institution between July 2010 and July 2012. The patients that had upper aero digestive tract bleeding that required an Otolaryngology consultation were identified. They were further investigated to determine location of bleed and procedures performed to control the bleeding. Results: Among the 37 consecutive patients on ECMO, 11 (30%) had upper aero digestive tract bleeding events. Of these 11, 6 (55%) were secondary to an iatrogenic incident, such as placing a nasogastric tube or transesophageal echo probe. All 11 patients were treated at bedside with conservative management and 2 were treated in the operating room. 72.7 % of patients treated with conservative management required repeated procedures due to incomplete hemostasis, compared to 0% of patients once surgical intervention was complete. Conclusions: Approximately one third of the ECMO patients developed upper aero digestive tract bleeding. This bleeding should be controlled in a timely manner otherwise it may result in massive transfusions. Delaying intervention or conservative management may not be effective. We recommend surgical intervention if the initial conservative management failed and continued to bleed for more than 24-36 hours
Proteinic Geontopower
PGP is a study of how we come into intimate contact with capitalism through our digestive tract. It is a study of the increasing valuing of protein in contemporary diet culture, focusing on how this phenomenon has resulted in mass-scale global soya production. Protein synthesis and distribution are rearticulated in this work as a set of molecular transactions enacted within/out bodies, moving loosely through ligaments and industrial machinery.
PGP is a speculative exercise in communing with a damaged planet through our daily ingestions
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