4 research outputs found
Automated Detection of High-Frequency Oscillations in Epilepsy Based on a Convolutional Neural Network
Epilepsy is one of the most common chronic neurological diseases. High-frequency oscillations (HFOs) have emerged as promising biomarkers for the epileptogenic zone. However, visual marking of HFOs is a time-consuming and laborious process. Several automated techniques have been proposed to detect HFOs, yet these are still far from being suitable for application in a clinical setting. Here, ripples and fast ripples from intracranial electroencephalograms were detected in six patients with intractable epilepsy using a convolutional neural network (CNN) method. This approach proved more accurate than using four other HFO detectors integrated in RIPPLELAB, providing a higher sensitivity (77.04% for ripples and 83.23% for fast ripples) and specificity (72.27% for ripples and 79.36% for fast ripples) for HFO detection. Furthermore, for one patient, the Cohen's kappa coefficients comparing automated detection and visual analysis results were 0.541 for ripples and 0.777 for fast ripples. Hence, our automated detector was capable of reliable estimates of ripples and fast ripples with higher sensitivity and specificity than four other HFO detectors. Our detector may be used to assist clinicians in locating epileptogenic zone in the future
Deep Learning Approaches for Seizure Video Analysis: A Review
Seizure events can manifest as transient disruptions in the control of
movements which may be organized in distinct behavioral sequences, accompanied
or not by other observable features such as altered facial expressions. The
analysis of these clinical signs, referred to as semiology, is subject to
observer variations when specialists evaluate video-recorded events in the
clinical setting. To enhance the accuracy and consistency of evaluations,
computer-aided video analysis of seizures has emerged as a natural avenue. In
the field of medical applications, deep learning and computer vision approaches
have driven substantial advancements. Historically, these approaches have been
used for disease detection, classification, and prediction using diagnostic
data; however, there has been limited exploration of their application in
evaluating video-based motion detection in the clinical epileptology setting.
While vision-based technologies do not aim to replace clinical expertise, they
can significantly contribute to medical decision-making and patient care by
providing quantitative evidence and decision support. Behavior monitoring tools
offer several advantages such as providing objective information, detecting
challenging-to-observe events, reducing documentation efforts, and extending
assessment capabilities to areas with limited expertise. The main applications
of these could be (1) improved seizure detection methods; (2) refined semiology
analysis for predicting seizure type and cerebral localization. In this paper,
we detail the foundation technologies used in vision-based systems in the
analysis of seizure videos, highlighting their success in semiology detection
and analysis, focusing on work published in the last 7 years. Additionally, we
illustrate how existing technologies can be interconnected through an
integrated system for video-based semiology analysis.Comment: Accepted in Epilepsy & Behavio