Student Galapagonian Shenanigans

Postcard from Robin Cone-Murakami, during the Linfield College Semester Abroad Program at the Galapagos Academic Institute for the Arts and Sciences in Ecuado

Transverse Momentum Dependent Light-Cone Wave Function of B-Meson and Relation to the Momentum Integrated One

A direct generalization of the transverse momentum integrated(TMI) light-cone wave function to define a transverse momentum dependent(TMD) light-cone wave function will cause light-cone singularities and they spoil TMD factorization. We motivate a definition in which the light-cone singularities are regularized with non-light like Wilson lines. The defined TMD light-cone wave function has some interesting relations to the corresponding TMI one. When the transverse momentum is very large, the TMD light-cone wave function is determined perturbatively in term of the TMI one. In the impact $b$-space with a small $b$, the TMD light-cone wave function can be factorized in terms of the TMI one. In this letter we study these relations. By-products of our study are the renormalization evolution of the TMI light-cone wave function and the Collins-Soper equation of the TMD light-cone wave function, the later will be useful for resumming Sudakov logarithms.Comment: Minor change in text, 7 pages, two figure

The Regulatory Review Process in South Africa: Challenges and Opportunities for a New Improved System.

BACKGROUND: The aims of this study were to assess the regulatory review process in South Africa from 2015 to 2017, identify the key milestones and timelines; evaluate the effectiveness of measures to ensure consistency, transparency, timeliness, and predictability in the review process; and to provide recommendations for enhanced regulatory practices. METHODS: A questionnaire was completed by the Medicines Control Council (MCC) to describe the organization of the authority, record key milestones and timelines in the review process and to identify good review practices (GRevPs). RESULTS: Currently, the MCC conducts a full assessment of quality, efficacy, and safety data in the review of all applications. The overall regulatory median approval time decreased by 14% in 2017 (1411 calendar days) compared with that of 2016, despite the 27% increase in the number of applications. However, the MCC has no target for overall approval time of new active substance applications and no targets for key review milestones. Guidelines, standard operating procedures, and review templates are in place, while the formal implementation of GRevPs and the application of an electronic document management system are planned for the near future. CONCLUSIONS: As the MCC transitions to the newly established South Africa Health Products Regulatory Authority, it would be crucial for the authority to recognize the opportunities for an enhanced regulatory review and should consider models such as abridged assessment, which encompass elements of risk stratification and reliance. It is hoped that resource constraints may then be alleviated and capacity developed to meet target timelines.Peer reviewedFinal Published versio

Process for control of cell division

A method of controlling mitosis of biological cells was developed, which involved inducing a change in the intracellular ionic hierarchy accompanying the cellular electrical transmembrane potential difference (Esubm) of the cells. The ionic hierarchy may be varied by imposing changes on the relative concentrations of Na(+), K(+) and Cl(-), or by directly imposing changes in the physical Esubm level across the cell surface