Classification of Arrhythmia by Using Deep Learning with 2-D ECG Spectral Image Representation

The electrocardiogram (ECG) is one of the most extensively employed signals used in the diagnosis and prediction of cardiovascular diseases (CVDs). The ECG signals can capture the heart's rhythmic irregularities, commonly known as arrhythmias. A careful study of ECG signals is crucial for precise diagnoses of patients' acute and chronic heart conditions. In this study, we propose a two-dimensional (2-D) convolutional neural network (CNN) model for the classification of ECG signals into eight classes; namely, normal beat, premature ventricular contraction beat, paced beat, right bundle branch block beat, left bundle branch block beat, atrial premature contraction beat, ventricular flutter wave beat, and ventricular escape beat. The one-dimensional ECG time series signals are transformed into 2-D spectrograms through short-time Fourier transform. The 2-D CNN model consisting of four convolutional layers and four pooling layers is designed for extracting robust features from the input spectrograms. Our proposed methodology is evaluated on a publicly available MIT-BIH arrhythmia dataset. We achieved a state-of-the-art average classification accuracy of 99.11\%, which is better than those of recently reported results in classifying similar types of arrhythmias. The performance is significant in other indices as well, including sensitivity and specificity, which indicates the success of the proposed method.Comment: 14 pages, 5 figures, accepted for future publication in Remote Sensing MDPI Journa

Heartbeat Anomaly Detection using Adversarial Oversampling

Cardiovascular diseases are one of the most common causes of death in the world. Prevention, knowledge of previous cases in the family, and early detection is the best strategy to reduce this fact. Different machine learning approaches to automatic diagnostic are being proposed to this task. As in most health problems, the imbalance between examples and classes is predominant in this problem and affects the performance of the automated solution. In this paper, we address the classification of heartbeats images in different cardiovascular diseases. We propose a two-dimensional Convolutional Neural Network for classification after using a InfoGAN architecture for generating synthetic images to unbalanced classes. We call this proposal Adversarial Oversampling and compare it with the classical oversampling methods as SMOTE, ADASYN, and RandomOversampling. The results show that the proposed approach improves the classifier performance for the minority classes without harming the performance in the balanced classes

On Merging Feature Engineering and Deep Learning for Diagnosis, Risk-Prediction and Age Estimation Based on the 12-Lead ECG

Objective: Machine learning techniques have been used extensively for 12-lead electrocardiogram (ECG) analysis. For physiological time series, deep learning (DL) superiority to feature engineering (FE) approaches based on domain knowledge is still an open question. Moreover, it remains unclear whether combining DL with FE may improve performance. Methods: We considered three tasks intending to address these research gaps: cardiac arrhythmia diagnosis (multiclass-multilabel classification), atrial fibrillation risk prediction (binary classification), and age estimation (regression). We used an overall dataset of 2.3M 12-lead ECG recordings to train the following models for each task: i) a random forest taking the FE as input was trained as a classical machine learning approach; ii) an end-to-end DL model; and iii) a merged model of FE+DL. Results: FE yielded comparable results to DL while necessitating significantly less data for the two classification tasks and it was outperformed by DL for the regression task. For all tasks, merging FE with DL did not improve performance over DL alone. Conclusion: We found that for traditional 12-lead ECG based diagnosis tasks DL did not yield a meaningful improvement over FE, while it improved significantly the nontraditional regression task. We also found that combining FE with DL did not improve over DL alone which suggests that the FE were redundant with the features learned by DL. Significance: Our findings provides important recommendations on what machine learning strategy and data regime to chose with respect to the task at hand for the development of new machine learning models based on the 12-lead ECG

Deep Learning in Cardiology

The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data. Deep learning has emerged as a more accurate and effective technology in a wide range of medical problems such as diagnosis, prediction and intervention. Deep learning is a representation learning method that consists of layers that transform the data non-linearly, thus, revealing hierarchical relationships and structures. In this review we survey deep learning application papers that use structured data, signal and imaging modalities from cardiology. We discuss the advantages and limitations of applying deep learning in cardiology that also apply in medicine in general, while proposing certain directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table

Artificial intelligence for heart rate variability analyzing with arrhythmias

Introduction. Existing standards of Heart Rate Variability (HRV) technology limit its use to sinus rhythm. A small number of extrasystoles is allowed, if the device used has special procedures for the detection and replacement of ectopic complexes. However, it is important to expand the indicated limits of the applicability of the HRV technology. This specially regards the cases when the HRV technology looks promising in the diagnostics, as, for example, in atrial fibrillation and atrial flutter. Materials and Methods. All ECG measurements were performed on XAI-MEDICA® equipment and software. Processing of the obtained RR Series was carried out using the software Kubios® HRV Standard. All recommended HRV characteristics for Time-Domain, Frequency-Domain and Nonlinear were calculated. The purpose of the work. The article presents an artificial intelligence (AI) procedure for detecting episodes of arrhythmias and reconstruction of core patient’s rhythm, and demonstrates the efficacy of its use for the HRV analysis in patients with varying degrees of arrhythmias. The results of the study. It was shown efficiency of developed artificial intelligence procedure for HRV analyzing of patients with different level of arrhythmias. These were demonstrated for Time-Domain, Frequency-Domain and Nonlinear methods. The direct inclusion into review of Arrhythmia Episodes and the use of the initial RR Series leads to a significant distortion of the results of the HRV analysis for the whole set of methods and for all considered options for arrhythmia. Conclusion. High efficacy of operation of the procedure AI core rhythm extraction from initial RR Series for patients with arrhythmia was reported in all cases