2 research outputs found
Challenges and characterization of a Biological system on Grid by means of the PhyloGrid application
In this work we present a new application that is being developed. PhyloGrid
is able to perform large-scale phylogenetic calculations as those that have
been made for estimating the phylogeny of all the sequences already stored in
the public NCBI database. The further analysis has been focused on checking the
origin of the HIV-1 disease by means of a huge number of sequences that sum up
to 2900 taxa. Such a study has been able to be done by the implementation of a
workflow in Taverna.Comment: 8 pages, 3 figures, appears in Proceedings of the First EELA-2
Conference, 200
Identificaci\'on de nuevos medicamentos a trav\'es de m\'etodos computacionales
Resumen: El desarrollo de nuevos medicamentos es un problema complejo que
carece de una soluci\'on \'unica y autom\'atica desde un punto de vista
computacional, debido a la carencia de programas que permitan manejar grandes
vol\'umenes de informaci\'on que est\'an distribuidos a lo largo de todo el
mundo entre m\'ultiples bases de datos. Por ello se describe una metodolog\'ia
que permita realizar experimentos in silico para la identificaci\'on actual de
nuevos medicamentos.
Abstract: The development of new drugs is a problem that nowadays has no
solution in terms of computational power due to the lack of software for
handling the big volume of available information; besides, these data are
stored in multiple formats and are distributed all around the world. To resolve
that, a development of an in silico drug design methodology.Comment: 20 pages, 4 figures, Spanish pape