262,442 research outputs found
Homeopathy for Breast Cancer Treatment Towards Hindu Women
This study was intended to reveal the facts regarding homeopathy in the breast cancer treatment for Hindu women in Buleleng regency. Through qualitative research methods, phenomenology theory, power and knowledge relation, health-seeking behavior, and the theory of health believe and explanatory model can reveal the reasons underlying the homeopathy occurrence in the breast cancer treatment, i.e., low medical awareness, accumulated awareness of praxis, and chemotherapy, confidence and treatment behaviors. Homeopathic practices in the breast cancer treatment included Balian/shaman (Balinese spiritual) as a traditional Balinese homeopath, breast cancer etiology, disease diagnosis, preliminary therapy, core therapy, and advanced therapy, and cure categories. Homeopathy in the breast cancer treatment has implications for the sustainability of the traditional Balinese treatment culture; implicates the patient in three ways, e.g., the delay and increased stage of cancer, giving psychic comfort to the patient without positive effects for healing, and providing psychic comfort as well as positive effects for healing; has medical implications as the antithesis of medical systems, media of reflection and instruction for the medical, and the desire emergence for some medical circles to combine medical and nonmedical
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UVA Assisted 4-Thiothymidine for Cancer Treatment
This article reviews the developments of 4-thiothymidine analogues, assisted with UVA light, as a novel cancer therapy. First, the key points on synthetic chemistry, photochemistry and cellular toxicity of 4-thiothymidine are summarized. As the chemical structure of 4-thiothymidine is very similar to that of its parent thymidine, thus 4-thiothymidine can be readily incorporated into cellular DNA, and with the help of thymidine kinase, much more preferably into cancerous DNA. Unlike thymidine, 4-thiothymdine can absorb strongly in UVA (longer wavelengths of UV) light. Thus UVA-assisted 4-thiothymidine offers an effective cancer treatment. Some underlying mechanisms of action by 4-thiothymidine/UVA and compares this cancer approach with the commonly used photodynamic therapy are discussed. The various interactions between 4-thiothymidine with human serum albumin are introduced. Finally, a short conclusion on the past efforts and a brief prospect for future work in this exciting research field are given
RNA Vaccine: novel approach for cancer treatment
Cancer is still an unsolved puzzle and a major cause of mortality and morbidity in the world. Today, about one in every thousand people is dying due to cancer. No effective agent has yet been found which can cure cancer in its metastatic stage. However, attempts in the shape of chemotherapy, immunotherapy and vaccines are made worldwide to find a remedy through a proper regimen. In continuation, tumor specific mRNA has been introduced as part of vaccines in recent days. It is mostly used in transfection with Dendritic Cells (DCs) for better effectiveness and safety. The DCs are selected for transfection because they are highly potent Antigen Presenting Cells (APCs) with the ability to take up & process tumor antigen in peripheral blood & tissues and can also migrate to the draining lymph nodes to present antigen to naïve T lymphocytes & induce the immune response.
Although initially the RNA vaccination was administered alone, due to its unstable and easily degradable nature, it was found to be quite less effective, which led it to be used in combination with some stability enhancers’ viz. RNA packaging in liposomes. They not only increased its stability, but even worked as active immune stimulators as well. RNA could remain stable. Although it showed significant promise in cancer treatment, immune suppression was noticed after vaccination. To enhance the effectiveness it is now being used in combination with few drugs viz. SUNITINIB which can reduce the suppressive effect of suppressor cells. It might be a good choice for combined therapy with RNA vaccine.

Cancer 2.0: A Summary of Recent Research
Outlines findings on Internet access and use among cancer patients compared with other chronic disease patients, the demand for health information online, the role of social network sites, and implications for cancer treatment and research
Women's Experiences of Sexual Problems After Cervical Cancer Treatment: Lessons From Indonesian Women
Cervical cancer remains the most common cancer among women. It is the second major cause of women’s deaths in Asia as well as in Indonesia. Cervical cancer treatment also raises issues of long-term physical, psychological, sexual, and social adaptation. The purpose of the study was to describe and to interpret the experiences of Indonesian women who have experienced sexual dysfunction after cervical cancer treatment. Thirteen Indonesian women who were participated in this study described their experiences on the first to two years after cervical cancer treatment. Data were collected through in-depth interviews. Four themes were identified (1) physical and psychological sexual complaints after cancer treatment; (2) negative effects of cancer treatment towards intimate relationship with their spouse; (3) efforts to overcome sexual problems; and (4) women’s needs for help to improve their sexual health. These studyfindings offer providing new insights into the experiences of Indonesian women with sexual health problems following cervical cancer treatment. This study can provide nurses and other health care providers with better understanding of the experiences, concern and needs of the cancer survivors
Repurposing metformin for cancer treatment: current clinical studies.
In recent years, several studies have presented evidence suggesting a potential role for metformin in anti-cancer therapy. Preclinical studies have demonstrated several anticancer molecular mechanisms of metformin including mTOR inhibition, cytotoxic effects, and immunomodulation. Epidemiologic data have demonstrated decreased cancer incidence and mortality in patients taking metformin. Several clinical trials, focused on evaluation of metformin as an anti-cancer agent are presently underway. Data published from a small number of completed trials has put forth intriguing results. Clinical trials in pre-surgical endometrial cancer patients exhibited a significant decrease in Ki67 with metformin monotherapy. Another interesting observation was made in patients with breast cancer, wherein a trend towards improvement in cancer proliferation markers was noted in patients without insulin resistance. Data on survival outcomes with the use of metformin as an anti-cancer agent is awaited. This manuscript will critically review the role of metformin as a potential cancer treatment
Last Year\u27s Virus, This Year\u27s Cancer Treatment
For hundreds of years, cancer has stumped medical professionals across the world as a cure evaded them. Now, a new approach to battling cancer has entered the arena: viruses. The concept of using one deadly disease to cure another has elevated cancer research to an entirely new level, with some promising results. This article examines recent research regarding the use of a modified measles virus in improving cancer outcomes
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Sexual well-being and diurnal cortisol after prostate cancer treatment.
Sexual dysfunction and psychological distress are common after prostate cancer. Research has not examined the role of neuroendocrine markers of stress (e.g. cortisol). This study examines whether sexual functioning or sexual bother is associated with diurnal cortisol. Men treated for prostate cancer completed the University of California-Los Angeles Prostate Cancer Index and provided saliva samples four times daily for cortisol assessment. Higher sexual bother, but not sexual functioning, was associated with steeper cortisol slope. Better sexual functioning, and not sexual bother, was significantly associated with the cortisol awakening response. Assessment of stress and stress-reducing interventions might be warranted in sexual rehabilitation after prostate cancer
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