9,000 research outputs found
Building Disease Detection Algorithms with Very Small Numbers of Positive Samples
Although deep learning can provide promising results in medical image
analysis, the lack of very large annotated datasets confines its full
potential. Furthermore, limited positive samples also create unbalanced
datasets which limit the true positive rates of trained models. As unbalanced
datasets are mostly unavoidable, it is greatly beneficial if we can extract
useful knowledge from negative samples to improve classification accuracy on
limited positive samples. To this end, we propose a new strategy for building
medical image analysis pipelines that target disease detection. We train a
discriminative segmentation model only on normal images to provide a source of
knowledge to be transferred to a disease detection classifier. We show that
using the feature maps of a trained segmentation network, deviations from
normal anatomy can be learned by a two-class classification network on an
extremely unbalanced training dataset with as little as one positive for 17
negative samples. We demonstrate that even though the segmentation network is
only trained on normal cardiac computed tomography images, the resulting
feature maps can be used to detect pericardial effusion and cardiac septal
defects with two-class convolutional classification networks
Abnormality Detection in Mammography using Deep Convolutional Neural Networks
Breast cancer is the most common cancer in women worldwide. The most common
screening technology is mammography. To reduce the cost and workload of
radiologists, we propose a computer aided detection approach for classifying
and localizing calcifications and masses in mammogram images. To improve on
conventional approaches, we apply deep convolutional neural networks (CNN) for
automatic feature learning and classifier building. In computer-aided
mammography, deep CNN classifiers cannot be trained directly on full mammogram
images because of the loss of image details from resizing at input layers.
Instead, our classifiers are trained on labelled image patches and then adapted
to work on full mammogram images for localizing the abnormalities.
State-of-the-art deep convolutional neural networks are compared on their
performance of classifying the abnormalities. Experimental results indicate
that VGGNet receives the best overall accuracy at 92.53\% in classifications.
For localizing abnormalities, ResNet is selected for computing class activation
maps because it is ready to be deployed without structural change or further
training. Our approach demonstrates that deep convolutional neural network
classifiers have remarkable localization capabilities despite no supervision on
the location of abnormalities is provided.Comment: 6 page
Efficient Active Learning for Image Classification and Segmentation using a Sample Selection and Conditional Generative Adversarial Network
Training robust deep learning (DL) systems for medical image classification
or segmentation is challenging due to limited images covering different disease
types and severity. We propose an active learning (AL) framework to select most
informative samples and add to the training data. We use conditional generative
adversarial networks (cGANs) to generate realistic chest xray images with
different disease characteristics by conditioning its generation on a real
image sample. Informative samples to add to the training set are identified
using a Bayesian neural network. Experiments show our proposed AL framework is
able to achieve state of the art performance by using about 35% of the full
dataset, thus saving significant time and effort over conventional methods
- …