Wireless Technologies for Implantable Devices

Wireless technologies are incorporated in implantable devices since at least the 1950s. With remote data collection and control of implantable devices, these wireless technologies help researchers and clinicians to better understand diseases and to improve medical treatments. Today, wireless technologies are still more commonly used for research, with limited applications in a number of clinical implantable devices. Recent development and standardization of wireless technologies present a good opportunity for their wider use in other types of implantable devices, which will significantly improve the outcomes of many diseases or injuries. This review briefly describes some common wireless technologies and modern advancements, as well as their strengths and suitability for use in implantable medical devices. The applications of these wireless technologies in treatments of orthopedic and cardiovascular injuries and disorders are described. This review then concludes with a discussion on the technical challenges and potential solutions of implementing wireless technologies in implantable devices

Healthy aims: developing new medical implants and diagnostic equipment

Healthy Aims is a €23-million, four-year project, funded under the EU’s Information Society Technology Sixth Framework program to develop intelligent medical implants and diagnostic systems (www.healthyaims.org). The project has 25 partners from 10 countries, including commercial, clinical, and research groups. This consortium represents a combination of disciplines to design and fabricate new medical devices and components as well as to test them in laboratories and subsequent clinical trials. The project focuses on medical implants for nerve stimulation and diagnostic equipment based on straingauge technology

An efficient telemetry system for restoring sight

PhD ThesisThe human nervous system can be damaged as a result of disease or trauma, causing conditions such as Parkinson’s disease. Most people try pharmaceuticals as a primary method of treatment. However, drugs cannot restore some cases, such as visual disorder. Alternatively, this impairment can be treated with electronic neural prostheses. A retinal prosthesis is an example of that for restoring sight, but it is not efficient and only people with retinal pigmentosa benefit from it. In such treatments, stimulation of the nervous system can be achieved by electrical or optical means. In the latter case, the nerves need to be rendered light sensitive via genetic means (optogenetics). High radiance photonic devices are then required to deliver light to the target tissue. Such optical approaches hold the potential to be more effective while causing less harm to the brain tissue. As these devices are implanted in tissue, wireless means need to be used to communicate with them. For this, IEEE 802.15.6 or Bluetooth protocols at 2.4GHz are potentially compatible with most advanced electronic devices, and are also safe and secure. Also, wireless power delivery can operate the implanted device. In this thesis, a fully wireless and efficient visual cortical stimulator was designed to restore the sight of the blind. This system is likely to address 40% of the causes of blindness. In general, the system can be divided into two parts, hardware and software. Hardware parts include a wireless power transfer design, the communication device, power management, a processor and the control unit, and the 3D design for assembly. The software part contains the image simplification, image compression, data encoding, pulse modulation, and the control system. Real-time video streaming is processed and sent over Bluetooth, and data are received by the LPC4330 six layer implanted board. After retrieving the compressed data, the processed data are again sent to the implanted electrode/optrode to stimulate the brain’s nerve cells

A LITERATURE REVIEW ON THE CURRENT STATE OF SECURITY AND PRIVACY OF MEDICAL DEVICES AND SENSORS WITH BLUETOOTH LOW ENERGY

Technology use in healthcare is an integral part of diagnosis and treatment. The use of technology in medical devices and sensors is growing. These devices include implantable medical devices, and consumer health and fitness tracking devices and applications. Bluetooth Low Energy (BLE) is the most commonly used communication method in medical devices and sensors. Security and privacy are important, especially in healthcare technologies that can impact morbidity. There is an increasing need to evaluate the security and privacy of healthcare technology, especially with devices and sensors that use Bluetooth Low Energy due to the increasing prevalence and use of medical devices and sensors. Therefore, more robust security analysis is needed to evaluate security and privacy aspects of medical devices and sensors that use Bluetooth Low Energy

A LITERATURE REVIEW ON THE CURRENT STATE OF SECURITY AND PRIVACY OF MEDICAL DEVICES AND SENSORS WITH BLUETOOTH LOW ENERGY

Technology use in healthcare is an integral part of diagnosis and treatment. The use of technology in medical devices and sensors is growing. These devices include implantable medical devices, and consumer health and fitness tracking devices and applications. Bluetooth Low Energy (BLE) is the most commonly used communication method in medical devices and sensors. Security and privacy are important, especially in healthcare technologies that can impact morbidity. There is an increasing need to evaluate the security and privacy of healthcare technology, especially with devices and sensors that use Bluetooth Low Energy due to the increasing prevalence and use of medical devices and sensors. Therefore, more robust security analysis is needed to evaluate security and privacy aspects of medical devices and sensors that use Bluetooth Low Energy

A Smart Implantable Bone Fixation Plate Providing Actuation and Load Monitoring for Orthopedic Fracture Healing

Fracture non-union occurs in roughly 5-10% of all fracture cases, and current interventions are both time-consuming and costly. There is therefore significant incentive to develop new tools to improve fracture healing outcomes. Several studies have shown that low-magnitude, high-frequency (LMHF) mechanical loading can promote faster healing and reduce the risk of refracture in critical-size long bone fractures. This is typically done using whole-body vibration, which may result in undesirable systemic effects on the rest of the body. This work discusses an implantable piezoelectric fixation plate that can both apply LMHF loading directly to the fracture site using flexible scheduling and indirectly monitor the progress of healing by using the increasing stiffness of the fracture callus. The design and performance of the piezoelectric bone plate show that the device can apply the target treatment and has the sensitivity to be used to observe the progress of healing. An accompanying telemetry system using BLE communication is also introduced which has a footprint of suitable size to be used in rodent studies and can provide the power necessary for piezoelectric actuation. These results pave the way for future studies regarding the efficacy and optimization of LMHF treatments in fracture healing models

Modelling and characterisation of antennas and propagation for body-centric wireless communication

PhDBody-Centric Wireless Communication (BCWC) is a central point in the development of fourth generation mobile communications. The continuous miniaturisation of sensors, in addition to the advancement in wearable electronics, embedded software, digital signal processing and biomedical technologies, have led to a new concept of usercentric networks, where devices can be carried in the user’s pockets, attached to the user’s body or even implanted. Body-centric wireless networks take their place within the personal area networks, body area networks and body sensor networks which are all emerging technologies that have a broad range of applications such as healthcare and personal entertainment. The major difference between BCWC and conventional wireless systems is the radio channel over which the communication takes place. The human body is a hostile environment from radio propagation perspective and it is therefore important to understand and characterise the effect of the human body on the antenna elements, the radio channel parameters and hence the system performance. This is presented and highlighted in the thesis through a combination of experimental and electromagnetic numerical investigations, with a particular emphasis to the numerical analysis based on the finite-difference time-domain technique. The presented research work encapsulates the characteristics of the narrowband (2.4 GHz) and ultra wide-band (3-10 GHz) on-body radio channels with respect to different digital phantoms, body postures, and antenna types hence highlighting the effect of subject-specific modelling, static and dynamic environments and antenna performance on the overall body-centric network. The investigations covered extend further to include in-body communications where the radio channel for telemetry with medical implants is also analysed by considering the effect of different digital phantoms on the radio channel characteristics. The study supports the significance of developing powerful and reliable numerical modelling to be used in conjunction with measurement campaigns for a comprehensive understanding of the radio channel in body-centric wireless communication. It also emphasises the importance of considering subject-specific electromagnetic modelling to provide a reliable prediction of the network performance