Multi-Atlas Segmentation using Partially Annotated Data: Methods and Annotation Strategies

Multi-atlas segmentation is a widely used tool in medical image analysis, providing robust and accurate results by learning from annotated atlas datasets. However, the availability of fully annotated atlas images for training is limited due to the time required for the labelling task. Segmentation methods requiring only a proportion of each atlas image to be labelled could therefore reduce the workload on expert raters tasked with annotating atlas images. To address this issue, we first re-examine the labelling problem common in many existing approaches and formulate its solution in terms of a Markov Random Field energy minimisation problem on a graph connecting atlases and the target image. This provides a unifying framework for multi-atlas segmentation. We then show how modifications in the graph configuration of the proposed framework enable the use of partially annotated atlas images and investigate different partial annotation strategies. The proposed method was evaluated on two Magnetic Resonance Imaging (MRI) datasets for hippocampal and cardiac segmentation. Experiments were performed aimed at (1) recreating existing segmentation techniques with the proposed framework and (2) demonstrating the potential of employing sparsely annotated atlas data for multi-atlas segmentation

Automatic annotation for weakly supervised learning of detectors

PhDObject detection in images and action detection in videos are among the most widely studied computer vision problems, with applications in consumer photography, surveillance, and automatic media tagging. Typically, these standard detectors are fully supervised, that is they require a large body of training data where the locations of the objects/actions in images/videos have been manually annotated. With the emergence of digital media, and the rise of high-speed internet, raw images and video are available for little to no cost. However, the manual annotation of object and action locations remains tedious, slow, and expensive. As a result there has been a great interest in training detectors with weak supervision where only the presence or absence of object/action in image/video is needed, not the location. This thesis presents approaches for weakly supervised learning of object/action detectors with a focus on automatically annotating object and action locations in images/videos using only binary weak labels indicating the presence or absence of object/action in images/videos. First, a framework for weakly supervised learning of object detectors in images is presented. In the proposed approach, a variation of multiple instance learning (MIL) technique for automatically annotating object locations in weakly labelled data is presented which, unlike existing approaches, uses inter-class and intra-class cue fusion to obtain the initial annotation. The initial annotation is then used to start an iterative process in which standard object detectors are used to refine the location annotation. Finally, to ensure that the iterative training of detectors do not drift from the object of interest, a scheme for detecting model drift is also presented. Furthermore, unlike most other methods, our weakly supervised approach is evaluated on data without manual pose (object orientation) annotation. Second, an analysis of the initial annotation of objects, using inter-class and intra-class cues, is carried out. From the analysis, a new method based on negative mining (NegMine) is presented for the initial annotation of both object and action data. The NegMine based approach is a much simpler formulation using only inter-class measure and requires no complex combinatorial optimisation but can still meet or outperform existing approaches including the previously pre3 sented inter-intra class cue fusion approach. Furthermore, NegMine can be fused with existing approaches to boost their performance. Finally, the thesis will take a step back and look at the use of generic object detectors as prior knowledge in weakly supervised learning of object detectors. These generic object detectors are typically based on sampling saliency maps that indicate if a pixel belongs to the background or foreground. A new approach to generating saliency maps is presented that, unlike existing approaches, looks beyond the current image of interest and into images similar to the current image. We show that our generic object proposal method can be used by itself to annotate the weakly labelled object data with surprisingly high accuracy

Multi-Modal Multi-Scale Deep Learning for Large-Scale Image Annotation

Image annotation aims to annotate a given image with a variable number of class labels corresponding to diverse visual concepts. In this paper, we address two main issues in large-scale image annotation: 1) how to learn a rich feature representation suitable for predicting a diverse set of visual concepts ranging from object, scene to abstract concept; 2) how to annotate an image with the optimal number of class labels. To address the first issue, we propose a novel multi-scale deep model for extracting rich and discriminative features capable of representing a wide range of visual concepts. Specifically, a novel two-branch deep neural network architecture is proposed which comprises a very deep main network branch and a companion feature fusion network branch designed for fusing the multi-scale features computed from the main branch. The deep model is also made multi-modal by taking noisy user-provided tags as model input to complement the image input. For tackling the second issue, we introduce a label quantity prediction auxiliary task to the main label prediction task to explicitly estimate the optimal label number for a given image. Extensive experiments are carried out on two large-scale image annotation benchmark datasets and the results show that our method significantly outperforms the state-of-the-art.Comment: Submited to IEEE TI