12,565 research outputs found
Classification of Radiology Reports Using Neural Attention Models
The electronic health record (EHR) contains a large amount of
multi-dimensional and unstructured clinical data of significant operational and
research value. Distinguished from previous studies, our approach embraces a
double-annotated dataset and strays away from obscure "black-box" models to
comprehensive deep learning models. In this paper, we present a novel neural
attention mechanism that not only classifies clinically important findings.
Specifically, convolutional neural networks (CNN) with attention analysis are
used to classify radiology head computed tomography reports based on five
categories that radiologists would account for in assessing acute and
communicable findings in daily practice. The experiments show that our CNN
attention models outperform non-neural models, especially when trained on a
larger dataset. Our attention analysis demonstrates the intuition behind the
classifier's decision by generating a heatmap that highlights attended terms
used by the CNN model; this is valuable when potential downstream medical
decisions are to be performed by human experts or the classifier information is
to be used in cohort construction such as for epidemiological studies
Predicting Pancreatic Cancer Using Support Vector Machine
This report presents an approach to predict pancreatic cancer using Support Vector Machine Classification algorithm. The research objective of this project it to predict pancreatic cancer on just genomic, just clinical and combination of genomic and clinical data. We have used real genomic data having 22,763 samples and 154 features per sample. We have also created Synthetic Clinical data having 400 samples and 7 features per sample in order to predict accuracy of just clinical data. To validate the hypothesis, we have combined synthetic clinical data with subset of features from real genomic data. In our results, we observed that prediction accuracy, precision, recall with just genomic data is 80.77%, 20%, 4%. Prediction accuracy, precision, recall with just synthetic clinical data is 93.33%, 95%, 30%. While prediction accuracy, precision, recall for combination of real genomic and synthetic clinical data is 90.83%, 10%, 5%. The combination of real genomic and synthetic clinical data decreased the accuracy since the genomic data is weakly correlated. Thus we conclude that the combination of genomic and clinical data does not improve pancreatic cancer prediction accuracy. A dataset with more significant genomic features might help to predict pancreatic cancer more accurately
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