63 research outputs found
A Novel Method for Epileptic Seizure Detection Using Coupled Hidden Markov Models
We propose a novel Coupled Hidden Markov Model to detect epileptic seizures
in multichannel electroencephalography (EEG) data. Our model defines a network
of seizure propagation paths to capture both the temporal and spatial evolution
of epileptic activity. To address the intractability introduced by the coupled
interactions, we derive a variational inference procedure to efficiently infer
the seizure evolution from spectral patterns in the EEG data. We validate our
model on EEG aquired under clinical conditions in the Epilepsy Monitoring Unit
of the Johns Hopkins Hospital. Using 5-fold cross validation, we demonstrate
that our model outperforms three baseline approaches which rely on a classical
detection framework. Our model also demonstrates the potential to localize
seizure onset zones in focal epilepsy.Comment: To appear in MICCAI 2018 Proceeding
Comparison of EEG based epilepsy diagnosis using neural networks and wavelet transform
Epilepsy is one of the common neurological disorders characterized by
recurrent and uncontrollable seizures, which seriously affect the life of
patients. In many cases, electroencephalograms signal can provide important
physiological information about the activity of the human brain which can be
used to diagnose epilepsy. However, visual inspection of a large number of
electroencephalogram signals is very time-consuming and can often lead to
inconsistencies in physicians' diagnoses. Quantification of abnormalities in
brain signals can indicate brain conditions and pathology so the
electroencephalogram (EEG) signal plays a key role in the diagnosis of
epilepsy. In this article, an attempt has been made to create a single
instruction for diagnosing epilepsy, which consists of two steps. In the first
step, a low-pass filter was used to preprocess the data and three separate
mid-pass filters for different frequency bands and a multilayer neural network
were designed. In the second step, the wavelet transform technique was used to
process data. In particular, this paper proposes a multilayer perceptron neural
network classifier for the diagnosis of epilepsy, that requires normal data and
epilepsy data for education, but this classifier can recognize normal
disorders, epilepsy, and even other disorders taught in educational examples.
Also, the value of using electroencephalogram signal has been evaluated in two
ways: using wavelet transform and non-using wavelet transform. Finally, the
evaluation results indicate a relatively uniform impact factor on the use or
non-use of wavelet transform on the improvement of epilepsy data functions, but
in the end, it was shown that the use of perceptron multilayer neural network
can provide a higher accuracy coefficient for experts.Comment: 8 pages, 4 tables, 3 figure
Increment entropy as a measure of complexity for time series
Entropy has been a common index to quantify the complexity of time series in
a variety of fields. Here, we introduce increment entropy to measure the
complexity of time series in which each increment is mapped into a word of two
letters, one letter corresponding to direction and the other corresponding to
magnitude. The Shannon entropy of the words is termed as increment entropy
(IncrEn). Simulations on synthetic data and tests on epileptic EEG signals have
demonstrated its ability of detecting the abrupt change, regardless of
energetic (e.g. spikes or bursts) or structural changes. The computation of
IncrEn does not make any assumption on time series and it can be applicable to
arbitrary real-world data.Comment: 12pages,7figure,2 table
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DETECTION OF EPILEPSY USING MACHINE LEARNING
Epilepsy is a complex neurological disorder characterized by recurrent seizures. An electroencephalogram (EEG) is typically used in the diagnosis of Epilepsy. Normally, EEGs are reviewed and analyzed by trained neurologists, but this can be time-consuming and error-prone. In this paper, we propose combining multiple classifiers in a multi-level fashion using stacked generalization to develop an effective solution for the detection of epilepsy using EEG data. Different classifiers such as Random Forest (RF), Recurrent Neural Networks (RNN), and XGBoost (XGB) were tested. The method was evaluated using Children’s Hospital Boston and Massachusetts Institute of Technology (CHB-MIT) dataset. The experimental results demonstrated that the proposed method outperforms existing methods, and achieved an accuracy of 96.166%
Early-stage tumor detection using photoacoustic microscopy: a pattern recognition approach
We report photoacoustic microscopy (PAM) of arteriovenous (AV) shunts in early stage tumors in vivo, and develop a pattern recognition framework for computerized tumor detection. Here, using a high-resolution photoacoustic microscope, we implement a new blood oxygenation (sO_2)-based disease marker induced by the AV shunt effect in tumor angiogenesis. We discovered a striking biological phenomenon: There can be two dramatically different sO_2 values in bloodstreams flowing side-by-side in a single vessel. By tracing abnormal sO_2 values in the blood vessels, we can identify a tumor region at an early stage. To further automate tumor detection based on our findings, we adopt widely used pattern recognition methods and develop an efficient computerized classification framework. The test result shows over 80% averaged detection accuracy with false positive contributing 18.52% of error test samples on a 50 PAM image dataset
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