A new kernel method for hyperspectral image feature extraction

Hyperspectral image provides abundant spectral information for remote discrimination of subtle differences in ground covers. However, the increasing spectral dimensions, as well as the information redundancy, make the analysis and interpretation of hyperspectral images a challenge. Feature extraction is a very important step for hyperspectral image processing. Feature extraction methods aim at reducing the dimension of data, while preserving as much information as possible. Particularly, nonlinear feature extraction methods (e.g. kernel minimum noise fraction (KMNF) transformation) have been reported to benefit many applications of hyperspectral remote sensing, due to their good preservation of high-order structures of the original data. However, conventional KMNF or its extensions have some limitations on noise fraction estimation during the feature extraction, and this leads to poor performances for post-applications. This paper proposes a novel nonlinear feature extraction method for hyperspectral images. Instead of estimating noise fraction by the nearest neighborhood information (within a sliding window), the proposed method explores the use of image segmentation. The approach benefits both noise fraction estimation and information preservation, and enables a significant improvement for classification. Experimental results on two real hyperspectral images demonstrate the efficiency of the proposed method. Compared to conventional KMNF, the improvements of the method on two hyperspectral image classification are 8 and 11%. This nonlinear feature extraction method can be also applied to other disciplines where high-dimensional data analysis is required

Accurate detection of dysmorphic nuclei using dynamic programming and supervised classification

A vast array of pathologies is typified by the presence of nuclei with an abnormal morphology. Dysmorphic nuclear phenotypes feature dramatic size changes or foldings, but also entail much subtler deviations such as nuclear protrusions called blebs. Due to their unpredictable size, shape and intensity, dysmorphic nuclei are often not accurately detected in standard image analysis routines. To enable accurate detection of dysmorphic nuclei in confocal and widefield fluorescence microscopy images, we have developed an automated segmentation algorithm, called Blebbed Nuclei Detector (BleND), which relies on two-pass thresholding for initial nuclear contour detection, and an optimal path finding algorithm, based on dynamic programming, for refining these contours. Using a robust error metric, we show that our method matches manual segmentation in terms of precision and outperforms state-of-the-art nuclear segmentation methods. Its high performance allowed for building and integrating a robust classifier that recognizes dysmorphic nuclei with an accuracy above 95%. The combined segmentation-classification routine is bound to facilitate nucleus-based diagnostics and enable real-time recognition of dysmorphic nuclei in intelligent microscopy workflows

A Review of Codebook Models in Patch-Based Visual Object Recognition

The codebook model-based approach, while ignoring any structural aspect in vision, nonetheless provides state-of-the-art performances on current datasets. The key role of a visual codebook is to provide a way to map the low-level features into a fixed-length vector in histogram space to which standard classifiers can be directly applied. The discriminative power of such a visual codebook determines the quality of the codebook model, whereas the size of the codebook controls the complexity of the model. Thus, the construction of a codebook is an important step which is usually done by cluster analysis. However, clustering is a process that retains regions of high density in a distribution and it follows that the resulting codebook need not have discriminant properties. This is also recognised as a computational bottleneck of such systems. In our recent work, we proposed a resource-allocating codebook, to constructing a discriminant codebook in a one-pass design procedure that slightly outperforms more traditional approaches at drastically reduced computing times. In this review we survey several approaches that have been proposed over the last decade with their use of feature detectors, descriptors, codebook construction schemes, choice of classifiers in recognising objects, and datasets that were used in evaluating the proposed methods