IEEE/ACM Transactions on Computational Biology and Bioinformatics: Vol. 10, No. 4, July-August 2013

1. Guest Editorial for Special Section on BSB 2012 - Marcilio C.P. de Souto and Maricel Kann / M. C. P. de Souto, M. Kann 2. Extending the Algebraic Formalism for Genome Rearrangements to Include Linear Chromosomes / Pedro Feijao, Joao Meidanis 3. 2D Meets 4G : G-Quadruplexes in RNA Secondary Structure Prediction / Ronny Lorenz, Stephan H. Bernhart, Jing Qin 4. Proximity Measures for Clustering Gene Expression Microarray data : A Validation Methodology and a Comparative Analysis/ Pablo A. Jaskowiak, Ricardo J.G.B. Campello, and Ivan G. Costa. 5. A Closed-Loo Control Scheme for Streering Stead States of Glycolysis and Glycogenolysis Pathway / S. Panja, S. Patra, A. Mukherjee, M. Basu, S. Sengupta, P. K. Dutta 6. A Divide and Conquer Approach for Construction of Large-Scale Signaling Networks from PPI and RNAi Data Using Linear Programing / O. E. Ozsoy, T. Can 7. A Knowledge-Based Multiple-Sequence Alignment Algorithm / K. D. Nguyen, Y. Pan 8. A Two-Phase Bio-NER System Based on Untegrated Classifiers and Multiagent Strategy / L. Li W Fan, D. Huang 9. An Improved Approximation Algorithm for Scaffold Filling to Maximize the Common Adjacencies / N. Liu, H. Jiang, D. Zhu, B. Zhu 10. An Optimization Rule for in Silico Identification of Targeted Overproduction in Metabolic Pathways / M. Das, C. A. Murthy, R. K. De 11. Algebraic Representation of Asynchronous Multiple-Valued Networks and Its Dynamics / C. Luo, X. Wang 12. Algorithms of Genome-scale Phylogenetics Using Gene Tree Parsimony / M. S. Bansal, O. Eulenstein 13. Analytical Solution of Steady-State Equations for Chemical Reaction Networks with Bilinear Rate Laws / A. M. Halasz, H. -J. Lai, M. McCabe Pryor, K. Radhakrishnan, J. S. Edwar