1 research outputs found
An SIS epidemic model with vaccination in a dynamical contact network of mobile individuals with heterogeneous spatial constraints
Network-based epidemic models have been extensively employed to understand
the spread of infectious diseases, but have generally overlooked the fact that
most realistic networks are dynamical rather than static. In this paper, we
study a susceptible-infected-susceptible epidemic model with vaccination in a
dynamical contact network of moving individuals, where we regard mobile
individuals as random walkers that are allowed to perform long-range jumps.
Different from previous studies of epidemics in a random walk network with a
constant interaction radius, we consider the scenario where the individuals
have a heterogeneous distribution of interaction radius and infected
individuals are vaccinated with a probability depending on the interaction
radius distribution. We derive the basic reproduction number
and explore the stability of disease-free and endemic equilibria of the model.
Both theoretical and simulation results reveal that the distribution of
individual interaction radius has significant effects on the basic reproduction
number and the epidemic prevalence. In general, the disease will break out more
readily in the population with a more heterogeneous radius distribution;
however resulting in a lower epidemic prevalence. Interestingly, the results
suggest that an optimal vaccination intervention for disease prevention and
control is achievable regardless of the radius distribution. Furthermore, some
interesting results on the structure of the underlying contact network are
shown to have strong correlation with the epidemic dynamics. This study
provides potential implications for developing efficient containment measures
against infectious disease while considering the spatial constraints of moving
individuals.Comment: 39 pages, 13figure