Large epidemic thresholds emerge in heterogeneous networks of heterogeneous nodes

One of the famous results of network science states that networks with heterogeneous connectivity are more susceptible to epidemic spreading than their more homogeneous counterparts. In particular, in networks of identical nodes it has been shown that network heterogeneity, i.e. a broad degree distribution, can lower the epidemic threshold at which epidemics can invade the system. Network heterogeneity can thus allow diseases with lower transmission probabilities to persist and spread. However, it has been pointed out that networks in which the properties of nodes are intrinsically heterogeneous can be very resilient to disease spreading. Heterogeneity in structure can enhance or diminish the resilience of networks with heterogeneous nodes, depending on the correlations between the topological and intrinsic properties. Here, we consider a plausible scenario where people have intrinsic differences in susceptibility and adapt their social network structure to the presence of the disease. We show that the resilience of networks with heterogeneous connectivity can surpass those of networks with homogeneous connectivity. For epidemiology, this implies that network heterogeneity should not be studied in isolation, it is instead the heterogeneity of infection risk that determines the likelihood of outbreaks

Epidemic processes in complex networks

In recent years the research community has accumulated overwhelming evidence for the emergence of complex and heterogeneous connectivity patterns in a wide range of biological and sociotechnical systems. The complex properties of real-world networks have a profound impact on the behavior of equilibrium and nonequilibrium phenomena occurring in various systems, and the study of epidemic spreading is central to our understanding of the unfolding of dynamical processes in complex networks. The theoretical analysis of epidemic spreading in heterogeneous networks requires the development of novel analytical frameworks, and it has produced results of conceptual and practical relevance. A coherent and comprehensive review of the vast research activity concerning epidemic processes is presented, detailing the successful theoretical approaches as well as making their limits and assumptions clear. Physicists, mathematicians, epidemiologists, computer, and social scientists share a common interest in studying epidemic spreading and rely on similar models for the description of the diffusion of pathogens, knowledge, and innovation. For this reason, while focusing on the main results and the paradigmatic models in infectious disease modeling, the major results concerning generalized social contagion processes are also presented. Finally, the research activity at the forefront in the study of epidemic spreading in coevolving, coupled, and time-varying networks is reported.Comment: 62 pages, 15 figures, final versio

Phase Transitions and Criticality in the Collective Behavior of Animals -- Self-organization and biological function

Collective behaviors exhibited by animal groups, such as fish schools, bird flocks, or insect swarms are fascinating examples of self-organization in biology. Concepts and methods from statistical physics have been used to argue theoretically about the potential consequences of collective effects in such living systems. In particular, it has been proposed that such collective systems should operate close to a phase transition, specifically a (pseudo-)critical point, in order to optimize their capability for collective computation. In this chapter, we will first review relevant phase transitions exhibited by animal collectives, pointing out the difficulties of applying concepts from statistical physics to biological systems. Then we will discuss the current state of research on the "criticality hypothesis", including methods for how to measure distance from criticality and specific functional consequences for animal groups operating near a phase transition. We will highlight the emerging view that de-emphasizes the optimality of being exactly at a critical point and instead explores the potential benefits of living systems being able to tune to an optimal distance from criticality. We will close by laying out future challenges for studying collective behavior at the interface of physics and biology.Comment: to appear in "Order, disorder, and criticality", vol. VII, World Scientific Publishin

Universal nonlinear infection kernel from heterogeneous exposure on higher-order networks

The colocation of individuals in different environments is an important prerequisite for exposure to infectious diseases on a social network. Standard epidemic models fail to capture the potential complexity of this scenario by (1) neglecting the higher-order structure of contacts which typically occur through environments like workplaces, restaurants, and households; and by (2) assuming a linear relationship between the exposure to infected contacts and the risk of infection. Here, we leverage a hypergraph model to embrace the heterogeneity of environments and the heterogeneity of individual participation in these environments. We find that combining heterogeneous exposure with the concept of minimal infective dose induces a universal nonlinear relationship between infected contacts and infection risk. Under nonlinear infection kernels, conventional epidemic wisdom breaks down with the emergence of discontinuous transitions, super-exponential spread, and hysteresis

Social contagion models on hypergraphs

Our understanding of the dynamics of complex networked systems has increased significantly in the last two decades. However, most of our knowledge is built upon assuming pairwise relations among the system's components. This is often an oversimplification, for instance, in social interactions that occur frequently within groups. To overcome this limitation, here we study the dynamics of social contagion on hypergraphs. We develop an analytical framework and provide numerical results for arbitrary hypergraphs, which we also support with Monte Carlo simulations. Our analyses show that the model has a vast parameter space, with first and second-order transitions, bi-stability, and hysteresis. Phenomenologically, we also extend the concept of latent heat to social contexts, which might help understanding oscillatory social behaviors. Our work unfolds the research line of higher-order models and the analytical treatment of hypergraphs, posing new questions and paving the way for modeling dynamical processes on these networks.Comment: 17 pages, including 14 figure

Invited review: Epidemics on social networks

Since its first formulations almost a century ago, mathematical models for disease spreading contributed to understand, evaluate and control the epidemic processes.They promoted a dramatic change in how epidemiologists thought of the propagation of infectious diseases.In the last decade, when the traditional epidemiological models seemed to be exhausted, new types of models were developed.These new models incorporated concepts from graph theory to describe and model the underlying social structure.Many of these works merely produced a more detailed extension of the previous results, but some others triggered a completely new paradigm in the mathematical study of epidemic processes. In this review, we will introduce the basic concepts of epidemiology, epidemic modeling and networks, to finally provide a brief description of the most relevant results in the field.Comment: 17 pages, 13 figure