7,947 research outputs found
On three soft rectangle packing problems with guillotine constraints
We investigate how to partition a rectangular region of length and
height into rectangles of given areas using
two-stage guillotine cuts, so as to minimize either (i) the sum of the
perimeters, (ii) the largest perimeter, or (iii) the maximum aspect ratio of
the rectangles. These problems play an important role in the ongoing Vietnamese
land-allocation reform, as well as in the optimization of matrix multiplication
algorithms. We show that the first problem can be solved to optimality in
, while the two others are NP-hard. We propose mixed
integer programming (MIP) formulations and a binary search-based approach for
solving the NP-hard problems. Experimental analyses are conducted to compare
the solution approaches in terms of computational efficiency and solution
quality, for different objectives
Automated Classification of Airborne Laser Scanning Point Clouds
Making sense of the physical world has always been at the core of mapping. Up
until recently, this has always dependent on using the human eye. Using
airborne lasers, it has become possible to quickly "see" more of the world in
many more dimensions. The resulting enormous point clouds serve as data sources
for applications far beyond the original mapping purposes ranging from flooding
protection and forestry to threat mitigation. In order to process these large
quantities of data, novel methods are required. In this contribution, we
develop models to automatically classify ground cover and soil types. Using the
logic of machine learning, we critically review the advantages of supervised
and unsupervised methods. Focusing on decision trees, we improve accuracy by
including beam vector components and using a genetic algorithm. We find that
our approach delivers consistently high quality classifications, surpassing
classical methods
Search based software engineering: Trends, techniques and applications
© ACM, 2012. This is the author's version of the work. It is posted here by permission of ACM for your personal use. Not for redistribution. The definitive version is available from the link below.In the past five years there has been a dramatic increase in work on Search-Based Software Engineering (SBSE), an approach to Software Engineering (SE) in which Search-Based Optimization (SBO) algorithms are used to address problems in SE. SBSE has been applied to problems throughout the SE lifecycle, from requirements and project planning to maintenance and reengineering. The approach is attractive because it offers a suite of adaptive automated and semiautomated solutions in situations typified by large complex problem spaces with multiple competing and conflicting objectives.
This article provides a review and classification of literature on SBSE. The work identifies research trends and relationships between the techniques applied and the applications to which they have been applied and highlights gaps in the literature and avenues for further research.EPSRC and E
A computational framework to emulate the human perspective in flow cytometric data analysis
Background: In recent years, intense research efforts have focused on developing methods for automated flow cytometric data analysis. However, while designing such applications, little or no attention has been paid to the human perspective that is absolutely central to the manual gating process of identifying and characterizing cell populations. In particular, the assumption of many common techniques that cell populations could be modeled reliably with pre-specified distributions may not hold true in real-life samples, which can have populations of arbitrary shapes and considerable inter-sample variation.
<p/>Results: To address this, we developed a new framework flowScape for emulating certain key aspects of the human perspective in analyzing flow data, which we implemented in multiple steps. First, flowScape begins with creating a mathematically rigorous map of the high-dimensional flow data landscape based on dense and sparse regions defined by relative concentrations of events around modes. In the second step, these modal clusters are connected with a global hierarchical structure. This representation allows flowScape to perform ridgeline analysis for both traversing the landscape and isolating cell populations at different levels of resolution. Finally, we extended manual gating with a new capacity for constructing templates that can identify target populations in terms of their relative parameters, as opposed to the more commonly used absolute or physical parameters. This allows flowScape to apply such templates in batch mode for detecting the corresponding populations in a flexible, sample-specific manner. We also demonstrated different applications of our framework to flow data analysis and show its superiority over other analytical methods.
<p/>Conclusions: The human perspective, built on top of intuition and experience, is a very important component of flow cytometric data analysis. By emulating some of its approaches and extending these with automation and rigor, flowScape provides a flexible and robust framework for computational cytomics
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