1,815 research outputs found

    Queue Tree Implementation for Bandwidth Management in Modern Campus Network Architecture

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    Bandwidth management in an institution becomes a fundamental need that must be managed properly. The continuous increase in the number of user, data and hardware technologies result in unequal distribution and bandwidth absorption. The increasingly diverse needs of the users in the virtual world require refined setting of bandwidth scheme. If bandwidth is not set properly, bandwidth can be accessed by multiple users. Institutions engaged in education consist of several parties such as employees, teachers and students (called student body). Queue implementation is a technique of dividing bandwidth according to the proportional needs of its users; moreover, this technique is able to work flexibly to organize and allocate bandwidth to end users. The ease of adding and reducing the amount of bandwidth becomes its main feature. The concept of campus network adopted from a Cisco fundamental system can serve as one model that can optimize the infrastructure and the distribution of bandwidth to end users. The method used in this research is employing direct observation, conducting interviews for problem identification and assigning the Internet service requirement and the availability of hardware and software resources. The optimization of bandwidth management by considering student body becomes the main objective. The implementation of queue on each network allows the distribution of bandwidth conforming the user satisfaction. Based on user satisfaction survey result, the user satisfaction level of Queue Tree implementation reached 59.2%

    Design and implementation of a generalized laboratory data model

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    <p>Abstract</p> <p>Background</p> <p>Investigators in the biological sciences continue to exploit laboratory automation methods and have dramatically increased the rates at which they can generate data. In many environments, the methods themselves also evolve in a rapid and fluid manner. These observations point to the importance of robust information management systems in the modern laboratory. Designing and implementing such systems is non-trivial and it appears that in many cases a database project ultimately proves unserviceable.</p> <p>Results</p> <p>We describe a general modeling framework for laboratory data and its implementation as an information management system. The model utilizes several abstraction techniques, focusing especially on the concepts of inheritance and meta-data. Traditional approaches commingle event-oriented data with regular entity data in <it>ad hoc </it>ways. Instead, we define distinct regular entity and event schemas, but fully integrate these via a standardized interface. The design allows straightforward definition of a "processing pipeline" as a sequence of events, obviating the need for separate workflow management systems. A layer above the event-oriented schema integrates events into a workflow by defining "processing directives", which act as automated project managers of items in the system. Directives can be added or modified in an almost trivial fashion, i.e., without the need for schema modification or re-certification of applications. Association between regular entities and events is managed via simple "many-to-many" relationships. We describe the programming interface, as well as techniques for handling input/output, process control, and state transitions.</p> <p>Conclusion</p> <p>The implementation described here has served as the Washington University Genome Sequencing Center's primary information system for several years. It handles all transactions underlying a throughput rate of about 9 million sequencing reactions of various kinds per month and has handily weathered a number of major pipeline reconfigurations. The basic data model can be readily adapted to other high-volume processing environments.</p

    Modular space station phase B extension period executive summary

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    A narrative summary is presented of technical, programmatic, and planning information developed during the space station definition study extension period. The modular space station is emphasized, but tasks pertaining to shuttle sorties missions and information management advanced development are included. A series of program options considering technical, schedule, and programmatic alternatives to the baseline program are defined and evaluated

    Development of microchannels of tunable stiffness for the study of migration of T-cells

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    Treballs Finals de Grau d'Enginyeria Biomèdica. Facultat de Medicina i Ciències de la Salut. Universitat de Barcelona. Curs: 2022-2023. Tutor/Director: Comelles Pujadas, JordiCell migration plays a crucial role in various physiological and pathological processes, including immune response and cancer metastasis. The complex interplay of the cancer cells with the microenvironment and the immune cell recruitment has emerged as a critical aspect in the progression of colorectal cancer. Cytotoxic T lymphocytes infiltrate the tumour microenvironment to exert anti-tumour immunity. To get to the tumour stroma, cells have to extravasate the vascular endothelial barrier in a process called transendothelial migration. We herein develop a microfluidic device capable of investigating the migration of T cells within an environment that closely mimics In vivo tissue characteristics. We have developed different protocols to fabricate microchannels of two different materials, polydimethylsiloxane, and polyacrylamide. Photolithography and novel microfabrication techniques have been employed to acquire confined microchannels. The microchannels successfully recreated key aspects of In vivo environment, enabling precise control of size and confinement. We have studied and confirmed the advantages of using hydrogels in microfluidics and their tuneable mechanical properties have been proved. Finally, the PDMS microfluidic chip has been tested with Jurkat cells and we have confirmed the suitability of the device for studying T cell migration profiles

    The Value of New Scientific Communication Models for Chemistry

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    This paper is intended as a starting point for discussion on the possible future of scientific communication in chemistry, the value of new models of scientific communication enabled by web based technologies, and the necessary future steps to achieve the benefits of those new models. It is informed by a NSF sponsored workshop that was held on October 23-24, 2008 in Washington D.C. It provides an overview on the chemical communication system in chemistry and describes efforts to enhance scientific communication by introducing new web-based models of scientific communication. It observes that such innovations are still embryonic and have not yet found broad adoption and acceptance by the chemical community. The paper proceeds to analyze the reasons for this by identifying specific characteristics of the chemistry domain that relate to its research practices and socio-economic organization. It hypothesizes how these may influence communication practices, and produce resistance to changes of the current system similar to those that have been successfully deployed in other sciences and which have been proposed by pioneers within chemistry.National Science Foundation, Microsof

    SWINE PRODUCTION NETWORKS IN MINNESOTA: RESOURCES FOR DECISION MAKING

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    Swine production networks are becoming a significant part of the Minnesota swine industry, with at least 30 production networks in operation as of late 1995. There are probably at least 450 producers involved, representing at least nine percent of the state s sow inventory. Not counted in these numbers are a few other networks involved only in data-sharing or marketing as well as a large number of farmer-to-farmer custom/contract arrangements. We interviewed 20 producers involved in networks. None of the networks we surveyed had been in operation very long, with most in business no more than a year or two. It is too early to predict what their long-term success will be. Most of the respondents seemed pleased with the arrangements so far. An example financial analysis of a 1,400 sow network is presented in the paper. Pig pricing formulas and custom rates are discussed for sharing risks among the farrower, nursery and finisher members of the network. The staff paper is 34 pages plus a 26 page annotated reading list of other publications on networking and segregated early weaning.Livestock Production/Industries,

    Biomimetic adhesion for transfer printing via microstructured surfaces

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    Demand for robust engineering techniques on the micro and nano scales has been steadily growing in the age of modern technology, not only because of the driving force to fit electronics into smaller form factors, but also for a variety of other applications, from devices with microfluidic functions to components whose interfacial behaviors are key features. In our research we attempted to develop a tool that facilitates assembly of a wide variety of devices on both conventional and novel surfaces in the hopes of both improving modern capabilities of technological fabrication, as well as opening up possibilities for new classes of devices that can be easily assembled on surfaces and in form factors that were not previously possible. In summary, primary benefit of this technology is the potential ability to fabricate a variety of electronic devices on any surface – thus expanding the versatility and ability to integrate different classes of technology in way that is not possible using modern, competing fabrication methods for micro and nano-scale chemical/electronic/mechanical devices. In the first two chapters, I will discuss background information relating to the basis and motivation for this technology, beginning with a summary of adhesion – how different types of adhesion occur and what their applicability is, with a focus on dispersive, or van der Waals adhesion – followed by a discussion of the field of biomimetics and how the study of naturally occurring dry adhesion techniques employed by animals such as geckos and insects has inspired a field of research into the use of dispersive intermolecular forces as an engineering solution for limitations of nanofabrication and assembly. In the following chapters I will describe our own group’s design, fabrication, and iii testing of a variety of microstructured surfaces intended to control adhesive strength by increasing it and decreasing it, as needed. Finally, I will present the results of our experiments and draw conclusions about the effectiveness and future potential of transfer printing via kinetically controlled microstructured stamps

    Curricular Optimization: Solving for the Optimal Student Success Pathway

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    Considering the significant investment of higher education made by students and their families, graduating in a timely manner is of the utmost importance. Delay attributed to drop out or the retaking of a course adds cost and negatively affects a student’s academic progression. Considering this, it becomes paramount for institutions to focus on student success in relation to term scheduling. Often overlooked, complexity of a course schedule may be one of the most important factors in whether or not a student successfully completes his or her degree. More often than not students entering an institution as a first time full time (FSFT) freshman follow the advised and published schedule given by administrators. Providing the optimal schedule that gives the student the highest probability of success is critical. In efforts to create this optimal schedule, this thesis introduces a novel optimization algorithm with the objective to separate courses which when taken together hurt students’ pass rates. Inversely, we combine synergistic relationships that improve a students probability for success when the courses are taken in the same semester. Using actual student data at the University of Kentucky, we categorically find these positive and negative combinations by analyzing recorded pass rates. Using Julia language on top of the Gurobi solver, we solve for the optimal degree plan of a student in the electrical engineering program using a linear and non-linear multi-objective optimization. A user interface is created for administrators to optimize their curricula at main.optimizeplans.com

    More than a decade of developmental gene expression atlases: where are we now?

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    To unravel regulatory networks of genes functioning during embryonic development, information on in situ gene expression is required. Enormous amounts of such data are available in literature, where each paper reports on a limited number of genes and developmental stages. The best way to make these data accessible is via spatio-temporal gene expression atlases. Eleven atlases, describing developing vertebrates and covering at least 100 genes, were reviewed. This review focuses on: (i) the used anatomical framework, (ii) the handling of input data and (iii) the retrieval of information. Our aim is to provide insights into both the possibilities of the atlases, as well as to describe what more than a decade of developmental gene expression atlases can teach us about the requirements of the design of the ‘ideal atlas’. This review shows that most ingredients needed to develop the ideal atlas are already applied to some extent in at least one of the discussed atlases. A review of these atlases shows that the ideal atlas should be based on a spatial framework, i.e. a series of 3D reference models, which is anatomically annotated using an ontology with sufficient resolution, both for relations as well as for anatomical terms

    Effects of Piconet Saturation on a Bluetooth Streaming Audio Channel

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    Bluetooth is a technology for wireless personal area networks (WPAN) that eliminates the need for cables, standardizes interfaces, and can automate many standard office processes such as sending and receiving email, synchronizing schedules, or exchanging business cards. With each workstation creating its own Bluetooth network, called a piconet, different Air Force environments have the potential, in some cases, to create more than 50 overlapping piconets, which significantly increases the potential for inter-piconet interference. This research investigates the effects of inter-piconet interference on a Bluetooth channel, streaming audio, offered at 24, 40, and 64 Kbps. It shows that as the number of overlapping piconets increases from zero to five, the effects on packet error rate are significant, climbing at times to just under 9%
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