Proceedings of the 28th Annual Hawaii international Conference on System Sciences- 1995 A Database for Globin Gene Expression Data

We describe a prototype database of sequence align-ments and experimental results for the P-like globin gene cluster of mammals. This data repository is in-tended to help the international community of globin-gene biologists to plan experiments, to design mod-els and, ultimately, to understand regulation of those genes. Moreover, the approaches and software de-veloped for th.is project will be applicable to other sequence-analysis problems, Our first steps were to develop a program that can simultaneously align a few very long sequences and to establish an e-mail server that formats any requested portion of the alignment, annotated to indicate highly-conserved regions and known sequence features. We are currently developing a World- Wide Web server that will provide access to the wealth of pertinent ex-perimental data, in register with the annotated align-ment, through a variety of query languages and graph-ical presentations.