A protected discharge facility for the elderly: design and validation of a working proof-of-concept

With the increasing share of elderly population worldwide, the need for assistive technologies to support clinicians in monitoring their health conditions is becoming more and more relevant. As a quantitative tool, geriatricians recently proposed the notion of frail elderly, which rapidly became a key element of clinical practices for the estimation of well-being in aging population. The evaluation of frailty is commonly based on self-reported outcomes and occasional physicians evaluations, and may therefore contain biased results. Another important aspect in the elderly population is hospitalization as a risk factor for patient\u2019s well being and public costs. Hospitalization is the main cause of functional decline, especially in older adults. The reduction of hospitalization time may allow an improvement of elderly health conditions and a reduction of hospital costs. Furthermore, a gradual transition from a hospital environment to a home-like one, can contribute to the weaning of the patient from a condition of hospitalization to a condition of discharge to his home. The advent of new technologies allows for the design and implementation of smart environments to monitor elderly health status and activities, fulfilling all the requirements of health and safety of the patients. From these starting points, in this thesis I present data-driven methodologies to automatically evaluate one of the main aspects contributing to the frailty estimation, i.e., the motility of the subject. First I will describe a model of protected discharge facility, realized in collaboration and within the E.O. Ospedali Galliera (Genoa, Italy), where patients can be monitored by a system of sensors while physicians and nurses have the opportunity to monitor them remotely. This sensorised facility is being developed to assist elderly users after they have been dismissed from the hospital and before they are ready to go back home, with the perspective of coaching them towards a healthy lifestyle. The facility is equipped with a variety of sensors (vision, depth, ambient and wearable sensors and medical devices), but in my thesis I primarily focus on RGB-D sensors and present visual computing tools to automatically estimate motility features. I provide an extensive system assessment I carried out onthree different experimental sessions with help of young as well as healthy aging volunteers. The results I present are in agreement with the assessment manually performed by physicians, showing the potential capability of my approach to complement current protocols of evaluation

An IoT-Aware Approach for Elderly-Friendly Cities

The ever-growing life expectancy of people requires the adoption of proper solutions for addressing the particular needs of elderly people in a sustainable way, both from service provision and economic point of view. Mild cognitive impairments and frailty are typical examples of elderly conditions which, if not timely addressed, can turn out into more complex diseases that are harder and costlier to treat. Information and communication technologies, and in particular Internet of Things technologies, can foster the creation of monitoring and intervention systems, both on an ambient-assisted living and smart city scope, for early detecting behavioral changes in elderly people. This allows to timely detect any potential risky situation and properly intervene, with benefits in terms of treatment's costs. In this context, as part of the H2020-funded City4Age project, this paper presents the data capturing and data management layers of the whole City4Age platform. In particular, this paper deals with an unobtrusive data gathering system implementation to collect data about daily activities of elderly people, and with the implementation of the related linked open data (LOD)-based data management system. The collected data are then used by other layers of the platform to perform risk detection algorithms and generate the proper customized interventions. Through the validation of some use-cases, it is demonstrated how this scalable approach, also characterized by unobtrusive and low-cost sensing technologies, can produce data with a high level of abstraction useful to define a risk profile of each elderly person

A Multidisciplinary Approach to Capability in Age and Ageing

This open access book provides insight on how to interpret capability in ageing – one’s individual ability to perform actions in order to reach goals one has reason to value – from a multidisciplinary approach. With for the first time in history there being more people in the world aged 60 years and over than there are children below the age of 5, the book describes this demographic trends as well as the large global challenges and important societal implications this will have such as a worldwide increase in the number of persons affected with dementia, and in the ratio of retired persons to those still in the labor market. Through contributions from many different research areas, it discussed how capability depends on interactions between the individual (e.g. health, genetics, personality, intellectual capacity), environment (e.g. family, friends, home, work place), and society (e.g. political decisions, ageism, historical period). The final chapter summarizes the differences and similarities in these contributions. As such this book provides an interesting read for students, teachers and researchers at different levels and from different fields interested in capability and multidisciplinary research

A Multidisciplinary Approach to Capability in Age and Ageing

This open access book provides insight on how to interpret capability in ageing – one’s individual ability to perform actions in order to reach goals one has reason to value – from a multidisciplinary approach. With for the first time in history there being more people in the world aged 60 years and over than there are children below the age of 5, the book describes this demographic trends as well as the large global challenges and important societal implications this will have such as a worldwide increase in the number of persons affected with dementia, and in the ratio of retired persons to those still in the labor market. Through contributions from many different research areas, it discussed how capability depends on interactions between the individual (e.g. health, genetics, personality, intellectual capacity), environment (e.g. family, friends, home, work place), and society (e.g. political decisions, ageism, historical period). The final chapter summarizes the differences and similarities in these contributions. As such this book provides an interesting read for students, teachers and researchers at different levels and from different fields interested in capability and multidisciplinary research

Smart Sensors for Healthcare and Medical Applications

This book focuses on new sensing technologies, measurement techniques, and their applications in medicine and healthcare. Specifically, the book briefly describes the potential of smart sensors in the aforementioned applications, collecting 24 articles selected and published in the Special Issue “Smart Sensors for Healthcare and Medical Applications”. We proposed this topic, being aware of the pivotal role that smart sensors can play in the improvement of healthcare services in both acute and chronic conditions as well as in prevention for a healthy life and active aging. The articles selected in this book cover a variety of topics related to the design, validation, and application of smart sensors to healthcare

New Trends in Cognitive Ageing and Mild Cognitive Impairment

This book focuses on the process of cognitive ageing, considering the increase in cognitive impairment associated with the aging of the population and the related care impact. Special attention is given to cognitive health changes linked to the increase in life expectancy, including the role of subjective factors; the link between cognitive function, mobility and functionality; and the potential role of digital technologies, including computerized cognitive tests and virtual reality environments

Stochastic Methods for Fine-Grained Image Segmentation and Uncertainty Estimation in Computer Vision

In this dissertation, we exploit concepts of probability theory, stochastic methods and machine learning to address three existing limitations of deep learning-based models for image understanding. First, although convolutional neural networks (CNN) have substantially improved the state of the art in image understanding, conventional CNNs provide segmentation masks that poorly adhere to object boundaries, a critical limitation for many potential applications. Second, training deep learning models requires large amounts of carefully selected and annotated data, but large-scale annotation of image segmentation datasets is often prohibitively expensive. And third, conventional deep learning models also lack the capability of uncertainty estimation, which compromises both decision making and model interpretability. To address these limitations, we introduce the Region Growing Refinement (RGR) algorithm, an unsupervised post-processing algorithm that exploits Monte Carlo sampling and pixel similarities to propagate high-confidence labels into regions of low-confidence classification. The probabilistic Region Growing Refinement (pRGR) provides RGR with a rigorous mathematical foundation that exploits concepts of Bayesian estimation and variance reduction techniques. Experiments demonstrate both the effectiveness of (p)RGR for the refinement of segmentation predictions, as well as its suitability for uncertainty estimation, since its variance estimates obtained in the Monte Carlo iterations are highly correlated with segmentation accuracy. We also introduce FreeLabel, an intuitive open-source web interface that exploits RGR to allow users to obtain high-quality segmentation masks with just a few freehand scribbles, in a matter of seconds. Designed to benefit the computer vision community, FreeLabel can be used for both crowdsourced or private annotation and has a modular structure that can be easily adapted for any image dataset. The practical relevance of methods developed in this dissertation are illustrated through applications on agricultural and healthcare-related domains. We have combined RGR and modern CNNs for fine segmentation of fruit flowers, motivated by the importance of automated bloom intensity estimation for optimization of fruit orchard management and, possibly, automatizing procedures such as flower thinning and pollination. We also exploited an early version of FreeLabel to annotate novel datasets for segmentation of fruit flowers, which are currently publicly available. Finally, this dissertation also describes works on fine segmentation and gaze estimation for images collected from assisted living environments, with the ultimate goal of assisting geriatricians in evaluating health status of patients in such facilities