44 research outputs found
Non-linear adaptive control inspired by neuromuscular systems
Current paradigms for neuromorphic computing focus on internal computing mechanisms, for instance using spiking-neuron models. In this study, we propose to exploit what is known about neuro-mechanical control, exploiting the mechanisms of neural ensembles and recruitment, combined with the use of second-order overdamped impulse responses corresponding to the mechanical twitches of muscle-fiber groups. Such systems may be used for controlling any analog process, by realizing three aspects: Timing, output quantity representation and wave-shape approximation. We present an electronic based model implementing a single motor unit for twitch generation. Such units can be used to construct random ensembles, separately for an agonist and antagonist 'muscle'. Adaptivity is realized by assuming a multi-state memristive system for determining time constants in the circuit. Using (Spice)-based simulations, several control tasks were implemented which involved timing, amplitude and wave shape: The inverted pendulum task, the 'whack-a-mole' task and a handwriting simulation. The proposed model can be used for both electric-to-electronic as well as electric-to-mechanical tasks. In particular, the ensemble-based approach and local adaptivity may be of use in future multi-fiber polymer or multi-actuator pneumatic artificial muscles, allowing for robust control under varying conditions and fatigue, as is the case in biological muscles
Behavior quantification as the missing link between fields: Tools for digital psychiatry and their role in the future of neurobiology
The great behavioral heterogeneity observed between individuals with the same
psychiatric disorder and even within one individual over time complicates both
clinical practice and biomedical research. However, modern technologies are an
exciting opportunity to improve behavioral characterization. Existing
psychiatry methods that are qualitative or unscalable, such as patient surveys
or clinical interviews, can now be collected at a greater capacity and analyzed
to produce new quantitative measures. Furthermore, recent capabilities for
continuous collection of passive sensor streams, such as phone GPS or
smartwatch accelerometer, open avenues of novel questioning that were
previously entirely unrealistic. Their temporally dense nature enables a
cohesive study of real-time neural and behavioral signals.
To develop comprehensive neurobiological models of psychiatric disease, it
will be critical to first develop strong methods for behavioral quantification.
There is huge potential in what can theoretically be captured by current
technologies, but this in itself presents a large computational challenge --
one that will necessitate new data processing tools, new machine learning
techniques, and ultimately a shift in how interdisciplinary work is conducted.
In my thesis, I detail research projects that take different perspectives on
digital psychiatry, subsequently tying ideas together with a concluding
discussion on the future of the field. I also provide software infrastructure
where relevant, with extensive documentation.
Major contributions include scientific arguments and proof of concept results
for daily free-form audio journals as an underappreciated psychiatry research
datatype, as well as novel stability theorems and pilot empirical success for a
proposed multi-area recurrent neural network architecture.Comment: PhD thesis cop
Understanding Quantum Technologies 2022
Understanding Quantum Technologies 2022 is a creative-commons ebook that
provides a unique 360 degrees overview of quantum technologies from science and
technology to geopolitical and societal issues. It covers quantum physics
history, quantum physics 101, gate-based quantum computing, quantum computing
engineering (including quantum error corrections and quantum computing
energetics), quantum computing hardware (all qubit types, including quantum
annealing and quantum simulation paradigms, history, science, research,
implementation and vendors), quantum enabling technologies (cryogenics, control
electronics, photonics, components fabs, raw materials), quantum computing
algorithms, software development tools and use cases, unconventional computing
(potential alternatives to quantum and classical computing), quantum
telecommunications and cryptography, quantum sensing, quantum technologies
around the world, quantum technologies societal impact and even quantum fake
sciences. The main audience are computer science engineers, developers and IT
specialists as well as quantum scientists and students who want to acquire a
global view of how quantum technologies work, and particularly quantum
computing. This version is an extensive update to the 2021 edition published in
October 2021.Comment: 1132 pages, 920 figures, Letter forma
Intelligent Biosignal Processing in Wearable and Implantable Sensors
This reprint provides a collection of papers illustrating the state-of-the-art of smart processing of data coming from wearable, implantable or portable sensors. Each paper presents the design, databases used, methodological background, obtained results, and their interpretation for biomedical applications. Revealing examples are brain–machine interfaces for medical rehabilitation, the evaluation of sympathetic nerve activity, a novel automated diagnostic tool based on ECG data to diagnose COVID-19, machine learning-based hypertension risk assessment by means of photoplethysmography and electrocardiography signals, Parkinsonian gait assessment using machine learning tools, thorough analysis of compressive sensing of ECG signals, development of a nanotechnology application for decoding vagus-nerve activity, detection of liver dysfunction using a wearable electronic nose system, prosthetic hand control using surface electromyography, epileptic seizure detection using a CNN, and premature ventricular contraction detection using deep metric learning. Thus, this reprint presents significant clinical applications as well as valuable new research issues, providing current illustrations of this new field of research by addressing the promises, challenges, and hurdles associated with the synergy of biosignal processing and AI through 16 different pertinent studies. Covering a wide range of research and application areas, this book is an excellent resource for researchers, physicians, academics, and PhD or master students working on (bio)signal and image processing, AI, biomaterials, biomechanics, and biotechnology with applications in medicine
Identification des régimes et regroupement des séquences pour la prévision des marchés financiers
Abstract : Regime switching analysis is extensively advocated to capture complex behaviors
underlying financial time series for market prediction. Two main disadvantages in
current approaches of regime identification are raised in the literature: 1) the lack of
a mechanism for identifying regimes dynamically, restricting them to switching among
a fixed set of regimes with a static transition probability matrix; 2) failure to utilize
cross-sectional regime dependencies among time series, since not all the time series are
synchronized to the same regime. As the numerical time series can be symbolized into
categorical sequences, a third issue raises: 3) the lack of a meaningful and effective
measure of the similarity between chronological dependent categorical values, in order
to identify sequence clusters that could serve as regimes for market forecasting. In this
thesis, we propose a dynamic regime identification model that can identify regimes
dynamically with a time-varying transition probability, to address the first issue. For
the second issue, we propose a cluster-based regime identification model to account
for the cross-sectional regime dependencies underlying financial time series for market
forecasting. For the last issue, we develop a dynamic order Markov model, making
use of information underlying frequent consecutive patterns and sparse patterns, to
identify the clusters that could serve as regimes identified on categorized financial time
series. Experiments on synthetic and real-world datasets show that our two regime
models show good performance on both regime identification and forecasting, while
our dynamic order Markov clustering model also demonstrates good performance on
identifying clusters from categorical sequences.L'analyse de changement de régime est largement préconisée pour capturer les comportements complexes sous-jacents aux séries chronologiques financières pour la prédiction du marché. Deux principaux problèmes des approches actuelles d'identifica-tion de régime sont soulevés dans la littérature. Il s’agit de: 1) l'absence d'un mécanisme d'identification dynamique des régimes. Ceci limite la commutation entre un ensemble fixe de régimes avec une matrice de probabilité de transition statique; 2) l’incapacité à utiliser les dépendances transversales des régimes entre les séries chronologiques, car toutes les séries chronologiques ne sont pas synchronisées sur le même régime. Étant donné que les séries temporelles numériques peuvent être symbolisées en séquences catégorielles, un troisième problème se pose: 3) l'absence d'une mesure significative et efficace de la similarité entre les séries chronologiques dépendant des valeurs catégorielles pour identifier les clusters de séquences qui pourraient servir de régimes de prévision du marché. Dans cette thèse, nous proposons un modèle d'identification de régime dynamique qui identifie dynamiquement des régimes avec une probabilité de transition variable dans le temps afin de répondre au premier problème. Ensuite, pour adresser le deuxième problème, nous proposons un modèle d'identification de régime basé sur les clusters. Notre modèle considère les dépendances transversales des régimes sous-jacents aux séries chronologiques financières avant d’effectuer la prévision du marché. Pour terminer, nous abordons le troisième problème en développant un modèle de Markov d'ordre dynamique, en utilisant les informations sous-jacentes aux motifs consécutifs fréquents et aux motifs clairsemés, pour identifier les clusters qui peuvent servir de régimes identifiés sur des séries chronologiques financières catégorisées. Nous avons mené des expériences sur des ensembles de données synthétiques et du monde réel. Nous démontrons que nos deux modèles de régime présentent de bonnes performances à la fois en termes d'identification et de prévision de régime, et notre modèle de clustering de Markov d'ordre dynamique produit également de bonnes performances dans l'identification de clusters à partir de séquences catégorielles
Lived Religion in the Ancient Mediterranean World
The Lived Ancient Religion project has radically changed perspectives on ancient religions and their supposedly personal or public character. This volume applies and further develops these methodological tools, new perspectives and new questions. The religious transformations of the Roman Imperial period appear in new light and more nuances by comparative confrontation and the integration of many disciplines. The contributions are written by specialists from a variety of disciplinary contexts (Jewish Studies, Theology, Classics, Early Christian Studies) dealing with the history of religion of the Mediterranean, West-Asian, and European area from the (late) Hellenistic period to the (early) Middle Ages and shaped by their intensive exchange. From the point of view of their respective fields of research, the contributors engage with discourses on agency, embodiment, appropriation and experience. They present innovative research in four fields also of theoretical debate, which are “Experiencing the Religious”, “Switching the Code”, „A Thing Called Body“ and “Commemorating the Moment”
Reinforcement Learning
Brains rule the world, and brain-like computation is increasingly used in computers and electronic devices. Brain-like computation is about processing and interpreting data or directly putting forward and performing actions. Learning is a very important aspect. This book is on reinforcement learning which involves performing actions to achieve a goal. The first 11 chapters of this book describe and extend the scope of reinforcement learning. The remaining 11 chapters show that there is already wide usage in numerous fields. Reinforcement learning can tackle control tasks that are too complex for traditional, hand-designed, non-learning controllers. As learning computers can deal with technical complexities, the tasks of human operators remain to specify goals on increasingly higher levels. This book shows that reinforcement learning is a very dynamic area in terms of theory and applications and it shall stimulate and encourage new research in this field
Epilepsy
With the vision of including authors from different parts of the world, different educational backgrounds, and offering open-access to their published work, InTech proudly presents the latest edited book in epilepsy research, Epilepsy: Histological, electroencephalographic, and psychological aspects. Here are twelve interesting and inspiring chapters dealing with basic molecular and cellular mechanisms underlying epileptic seizures, electroencephalographic findings, and neuropsychological, psychological, and psychiatric aspects of epileptic seizures, but non-epileptic as well
Biological and biomimetic machine learning for automatic classification of human gait
Machine learning (ML) research has benefited from a deep understanding of biological mechanisms that have evolved to perform comparable tasks. Recent successes of ML models, superseding human performance in human perception based tasks has garnered interest in improving them further. However, the approach to improving ML models tends to be unstructured, particularly for the models that aim to mimic biology. This thesis proposes and applies a bidirectional learning paradigm to streamline the process of improving ML models’ performance in classification of a task, which humans are already adept at. The approach is validated taking human gait classification as the exemplar task. This paradigm possesses the additional benefit of investigating underlying mechanisms in human perception (HP) using the ML models. Assessment of several biomimetic (BM) and non-biomimetic (NBM) machine learning models on an intrinsic feature of gait, namely the gender of the walker, establishes a functional overlap in the perception of gait between HP and BM, selecting the Long-Short-Term-Memory (LSTM) architecture as the BM of choice for this study, when compared with other models such as support vector machines, decision trees and multi-layer perceptron models. Psychophysics and computational experiments are conducted to understand the overlap between human and machine models. The BM and HP derived from psychophysics experiments, share qualitatively similar profiles of gender classification accuracy across varying stimulus exposure durations. They also share the preference for motion-based cues over structural cues (BM=H>NBM). Further evaluation reveals a human-like expression of the inversion effect, a well-studied cognitive bias in HP that reduces the gender classification accuracy to 37% (p<0.05, chance at 50%) when exposed to inverted stimulus. Its expression in the BM supports the argument for learned rather than hard-wired mechanisms in HP. Particularly given the emergence of the effect in every BM, after training multiple randomly initialised BM models without prior anthropomorphic expectations of gait.
The above aspects of HP, namely the preference for motion cues over structural cues and the lack of prior anthropomorphic expectations, were selected to improve BM performance. Representing gait explicitly as motion-based cues of a non-anthropomorphic, gender-neutral skeleton not only mitigates the inversion effect in BM, but also improves significantly the classification accuracy. In the case of gender classification of upright stimuli, mean accuracy improved by 6%, from 76% to 82% (F1,18 = 16, p<0.05). For inverted stimuli, mean accuracy improved by 45%, from 37% to 82% (F1,18 = 20, p<0.05). The model was further tested on a more challenging, extrinsic feature task; the classification of the emotional state of a walker. Emotions were visually induced in subjects through exposure to emotive or neutral images from the International Affective Picture System (IAPS) database. The classification accuracy of the BM was significantly above chance at 43% accuracy (p<0.05, chance at 33.3%). However, application of the proposed paradigm in further binary emotive state classification experiments, improved mean accuracy further by 23%, from 43% to 65% (F1,18 = 7.4, p<0.05) for the positive vs. neutral task. Results validate the proposed paradigm of concurrent bidirectional investigation of HP and BM for the classification of human gait, suggesting future applications for automating perceptual tasks for which the human brain and body has evolved