Prototype of running clinical trials in an untrustworthy environment using blockchain.

Monitoring and ensuring the integrity of data within the clinical trial process is currently not always feasible with the current research system. We propose a blockchain-based system to make data collected in the clinical trial process immutable, traceable, and potentially more trustworthy. We use raw data from a real completed clinical trial, simulate the trial onto a proof of concept web portal service, and test its resilience to data tampering. We also assess its prospects to provide a traceable and useful audit trail of trial data for regulators, and a flexible service for all members within the clinical trials network. We also improve the way adverse events are currently reported. In conclusion, we advocate that this service could offer an improvement in clinical trial data management, and could bolster trust in the clinical research process and the ease at which regulators can oversee trials

Storage Solutions for Big Data Systems: A Qualitative Study and Comparison

Big data systems development is full of challenges in view of the variety of application areas and domains that this technology promises to serve. Typically, fundamental design decisions involved in big data systems design include choosing appropriate storage and computing infrastructures. In this age of heterogeneous systems that integrate different technologies for optimized solution to a specific real world problem, big data system are not an exception to any such rule. As far as the storage aspect of any big data system is concerned, the primary facet in this regard is a storage infrastructure and NoSQL seems to be the right technology that fulfills its requirements. However, every big data application has variable data characteristics and thus, the corresponding data fits into a different data model. This paper presents feature and use case analysis and comparison of the four main data models namely document oriented, key value, graph and wide column. Moreover, a feature analysis of 80 NoSQL solutions has been provided, elaborating on the criteria and points that a developer must consider while making a possible choice. Typically, big data storage needs to communicate with the execution engine and other processing and visualization technologies to create a comprehensive solution. This brings forth second facet of big data storage, big data file formats, into picture. The second half of the research paper compares the advantages, shortcomings and possible use cases of available big data file formats for Hadoop, which is the foundation for most big data computing technologies. Decentralized storage and blockchain are seen as the next generation of big data storage and its challenges and future prospects have also been discussed

Security and Privacy for Green IoT-based Agriculture: Review, Blockchain solutions, and Challenges

open access articleThis paper presents research challenges on security and privacy issues in the field of green IoT-based agriculture. We start by describing a four-tier green IoT-based agriculture architecture and summarizing the existing surveys that deal with smart agriculture. Then, we provide a classification of threat models against green IoT-based agriculture into five categories, including, attacks against privacy, authentication, confidentiality, availability, and integrity properties. Moreover, we provide a taxonomy and a side-by-side comparison of the state-of-the-art methods toward secure and privacy-preserving technologies for IoT applications and how they will be adapted for green IoT-based agriculture. In addition, we analyze the privacy-oriented blockchain-based solutions as well as consensus algorithms for IoT applications and how they will be adapted for green IoT-based agriculture. Based on the current survey, we highlight open research challenges and discuss possible future research directions in the security and privacy of green IoT-based agriculture