3,765 research outputs found
Design and Evaluation of a Hardware System for Online Signal Processing within Mobile Brain-Computer Interfaces
Brain-Computer Interfaces (BCIs) sind innovative Systeme, die eine direkte Kommunikation zwischen dem Gehirn und externen Geräten ermöglichen. Diese Schnittstellen haben sich zu einer transformativen Lösung nicht nur für Menschen mit neurologischen Verletzungen entwickelt, sondern auch für ein breiteres Spektrum von Menschen, das sowohl medizinische als auch nicht-medizinische Anwendungen umfasst. In der Vergangenheit hat die Herausforderung, dass neurologische Verletzungen nach einer anfänglichen Erholungsphase statisch bleiben, die Forscher dazu veranlasst, innovative Wege zu beschreiten. Seit den 1970er Jahren stehen BCIs an vorderster Front dieser Bemühungen. Mit den Fortschritten in der Forschung haben sich die BCI-Anwendungen erweitert und zeigen ein großes Potenzial für eine Vielzahl von Anwendungen, auch für weniger stark eingeschränkte (zum Beispiel im Kontext von Hörelektronik) sowie völlig gesunde Menschen (zum Beispiel in der Unterhaltungsindustrie). Die Zukunft der BCI-Forschung hängt jedoch auch von der Verfügbarkeit zuverlässiger BCI-Hardware ab, die den Einsatz in der realen Welt gewährleistet.
Das im Rahmen dieser Arbeit konzipierte und implementierte CereBridge-System stellt einen bedeutenden Fortschritt in der Brain-Computer-Interface-Technologie dar, da es die gesamte Hardware zur Erfassung und Verarbeitung von EEG-Signalen in ein mobiles System integriert. Die Architektur der Verarbeitungshardware basiert auf einem FPGA mit einem ARM Cortex-M3 innerhalb eines heterogenen ICs, was Flexibilität und Effizienz bei der EEG-Signalverarbeitung gewährleistet. Der modulare Aufbau des Systems, bestehend aus drei einzelnen Boards, gewährleistet die Anpassbarkeit an unterschiedliche Anforderungen. Das komplette System wird an der Kopfhaut befestigt, kann autonom arbeiten, benötigt keine externe Interaktion und wiegt einschließlich der 16-Kanal-EEG-Sensoren nur ca. 56 g. Der Fokus liegt auf voller Mobilität.
Das vorgeschlagene anpassbare Datenflusskonzept erleichtert die Untersuchung und nahtlose Integration von Algorithmen und erhöht die Flexibilität des Systems. Dies wird auch durch die Möglichkeit unterstrichen, verschiedene Algorithmen auf EEG-Daten anzuwenden, um unterschiedliche Anwendungsziele zu erreichen. High-Level Synthesis (HLS) wurde verwendet, um die Algorithmen auf das FPGA zu portieren, was den Algorithmenentwicklungsprozess beschleunigt und eine schnelle Implementierung von Algorithmusvarianten ermöglicht. Evaluierungen haben gezeigt, dass das CereBridge-System in der Lage ist, die gesamte Signalverarbeitungskette zu integrieren, die für verschiedene BCI-Anwendungen erforderlich ist. Darüber hinaus kann es mit einer Batterie von mehr als 31 Stunden Dauerbetrieb betrieben werden, was es zu einer praktikablen Lösung für mobile Langzeit-EEG-Aufzeichnungen und reale BCI-Studien macht.
Im Vergleich zu bestehenden Forschungsplattformen bietet das CereBridge-System eine bisher unerreichte Leistungsfähigkeit und Ausstattung für ein mobiles BCI. Es erfüllt nicht nur die relevanten Anforderungen an ein mobiles BCI-System, sondern ebnet auch den Weg für eine schnelle Übertragung von Algorithmen aus dem Labor in reale Anwendungen. Im Wesentlichen liefert diese Arbeit einen umfassenden Entwurf für die Entwicklung und Implementierung eines hochmodernen mobilen EEG-basierten BCI-Systems und setzt damit einen neuen Standard für BCI-Hardware, die in der Praxis eingesetzt werden kann.Brain-Computer Interfaces (BCIs) are innovative systems that enable direct communication between the brain and external devices. These interfaces have emerged as a transformative solution not only for individuals with neurological injuries, but also for a broader range of individuals, encompassing both medical and non-medical applications. Historically, the challenge of neurological injury being static after an initial recovery phase has driven researchers to explore innovative avenues. Since the 1970s, BCIs have been at one forefront of these efforts. As research has progressed, BCI applications have expanded, showing potential in a wide range of applications, including those for less severely disabled (e.g. in the context of hearing aids) and completely healthy individuals (e.g. entertainment industry). However, the future of BCI research also depends on the availability of reliable BCI hardware to ensure real-world application.
The CereBridge system designed and implemented in this work represents a significant leap forward in brain-computer interface technology by integrating all EEG signal acquisition and processing hardware into a mobile system. The processing hardware architecture is centered around an FPGA with an ARM Cortex-M3 within a heterogeneous IC, ensuring flexibility and efficiency in EEG signal processing. The modular design of the system, consisting of three individual boards, ensures adaptability to different requirements. With a focus on full mobility, the complete system is mounted on the scalp, can operate autonomously, requires no external interaction, and weighs approximately 56g, including 16 channel EEG sensors.
The proposed customizable dataflow concept facilitates the exploration and seamless integration of algorithms, increasing the flexibility of the system. This is further underscored by the ability to apply different algorithms to recorded EEG data to meet different application goals. High-Level Synthesis (HLS) was used to port algorithms to the FPGA, accelerating the algorithm development process and facilitating rapid implementation of algorithm variants. Evaluations have shown that the CereBridge system is capable of integrating the complete signal processing chain required for various BCI applications. Furthermore, it can operate continuously for more than 31 hours with a 1800mAh battery, making it a viable solution for long-term mobile EEG recording and real-world BCI studies.
Compared to existing research platforms, the CereBridge system offers unprecedented performance and features for a mobile BCI. It not only meets the relevant requirements for a mobile BCI system, but also paves the way for the rapid transition of algorithms from the laboratory to real-world applications. In essence, this work provides a comprehensive blueprint for the development and implementation of a state-of-the-art mobile EEG-based BCI system, setting a new benchmark in BCI hardware for real-world applicability
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FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices
Single-molecule FRET (smFRET) has become a mainstream technique for studying biomolecular structural dynamics. The rapid and wide adoption of smFRET experiments by an ever-increasing number of groups has generated significant progress in sample preparation, measurement procedures, data analysis, algorithms and documentation. Several labs that employ smFRET approaches have joined forces to inform the smFRET community about streamlining how to perform experiments and analyze results for obtaining quantitative information on biomolecular structure and dynamics. The recent efforts include blind tests to assess the accuracy and the precision of smFRET experiments among different labs using various procedures. These multi-lab studies have led to the development of smFRET procedures and documentation, which are important when submitting entries into the archiving system for integrative structure models, PDB-Dev. This position paper describes the current ‘state of the art’ from different perspectives, points to unresolved methodological issues for quantitative structural studies, provides a set of ‘soft recommendations’ about which an emerging consensus exists, and lists openly available resources for newcomers and seasoned practitioners. To make further progress, we strongly encourage ‘open science’ practices
Multidisciplinary perspectives on Artificial Intelligence and the law
This open access book presents an interdisciplinary, multi-authored, edited collection of chapters on Artificial Intelligence (‘AI’) and the Law. AI technology has come to play a central role in the modern data economy. Through a combination of increased computing power, the growing availability of data and the advancement of algorithms, AI has now become an umbrella term for some of the most transformational technological breakthroughs of this age. The importance of AI stems from both the opportunities that it offers and the challenges that it entails. While AI applications hold the promise of economic growth and efficiency gains, they also create significant risks and uncertainty. The potential and perils of AI have thus come to dominate modern discussions of technology and ethics – and although AI was initially allowed to largely develop without guidelines or rules, few would deny that the law is set to play a fundamental role in shaping the future of AI. As the debate over AI is far from over, the need for rigorous analysis has never been greater. This book thus brings together contributors from different fields and backgrounds to explore how the law might provide answers to some of the most pressing questions raised by AI. An outcome of the Católica Research Centre for the Future of Law and its interdisciplinary working group on Law and Artificial Intelligence, it includes contributions by leading scholars in the fields of technology, ethics and the law.info:eu-repo/semantics/publishedVersio
Sound Event Detection by Exploring Audio Sequence Modelling
Everyday sounds in real-world environments are a powerful source of information by which humans can interact with their environments. Humans can infer what is happening around them by listening to everyday sounds. At the same time, it is a challenging task for a computer algorithm in a smart device to automatically recognise, understand, and interpret everyday sounds. Sound event detection (SED) is the process of transcribing an audio recording into sound event tags with onset and offset time values. This involves classification and segmentation of sound events in the given audio recording. SED has numerous applications in everyday life which include security and surveillance, automation, healthcare monitoring, multimedia information retrieval, and assisted living technologies. SED is to everyday sounds what automatic speech recognition (ASR) is to speech and automatic music transcription (AMT) is to music. The fundamental questions in designing a sound recognition system are, which portion of a sound event should the system analyse, and what proportion of a sound event should the system process in order to claim a confident detection of that particular sound event. While the classification of sound events has improved a lot in recent years, it is considered that the temporal-segmentation of sound events has not improved in the same extent. The aim of this thesis is to propose and develop methods to improve the segmentation and classification of everyday sound events in SED models. In particular, this thesis explores the segmentation of sound events by investigating audio sequence encoding-based and audio sequence modelling-based methods, in an effort to improve the overall sound event detection performance. In the first phase of this thesis, efforts are put towards improving sound event detection by explicitly conditioning the audio sequence representations of an SED model using sound activity detection (SAD) and onset detection. To achieve this, we propose multi-task learning-based SED models in which SAD and onset detection are used as auxiliary tasks for the SED task. The next part of this thesis explores self-attention-based audio sequence modelling, which aggregates audio representations based on temporal relations within and between sound events, scored on the basis of the similarity of sound event portions in audio event sequences. We propose SED models that include memory-controlled, adaptive, dynamic, and source separation-induced self-attention variants, with the aim to improve overall sound recognition
Modern computing: Vision and challenges
Over the past six decades, the computing systems field has experienced significant transformations, profoundly impacting society with transformational developments, such as the Internet and the commodification of computing. Underpinned by technological advancements, computer systems, far from being static, have been continuously evolving and adapting to cover multifaceted societal niches. This has led to new paradigms such as cloud, fog, edge computing, and the Internet of Things (IoT), which offer fresh economic and creative opportunities. Nevertheless, this rapid change poses complex research challenges, especially in maximizing potential and enhancing functionality. As such, to maintain an economical level of performance that meets ever-tighter requirements, one must understand the drivers of new model emergence and expansion, and how contemporary challenges differ from past ones. To that end, this article investigates and assesses the factors influencing the evolution of computing systems, covering established systems and architectures as well as newer developments, such as serverless computing, quantum computing, and on-device AI on edge devices. Trends emerge when one traces technological trajectory, which includes the rapid obsolescence of frameworks due to business and technical constraints, a move towards specialized systems and models, and varying approaches to centralized and decentralized control. This comprehensive review of modern computing systems looks ahead to the future of research in the field, highlighting key challenges and emerging trends, and underscoring their importance in cost-effectively driving technological progress
LIPIcs, Volume 251, ITCS 2023, Complete Volume
LIPIcs, Volume 251, ITCS 2023, Complete Volum
Effects of municipal smoke-free ordinances on secondhand smoke exposure in the Republic of Korea
ObjectiveTo reduce premature deaths due to secondhand smoke (SHS) exposure among non-smokers, the Republic of Korea (ROK) adopted changes to the National Health Promotion Act, which allowed local governments to enact municipal ordinances to strengthen their authority to designate smoke-free areas and levy penalty fines. In this study, we examined national trends in SHS exposure after the introduction of these municipal ordinances at the city level in 2010.MethodsWe used interrupted time series analysis to assess whether the trends of SHS exposure in the workplace and at home, and the primary cigarette smoking rate changed following the policy adjustment in the national legislation in ROK. Population-standardized data for selected variables were retrieved from a nationally representative survey dataset and used to study the policy action’s effectiveness.ResultsFollowing the change in the legislation, SHS exposure in the workplace reversed course from an increasing (18% per year) trend prior to the introduction of these smoke-free ordinances to a decreasing (−10% per year) trend after adoption and enforcement of these laws (β2 = 0.18, p-value = 0.07; β3 = −0.10, p-value = 0.02). SHS exposure at home (β2 = 0.10, p-value = 0.09; β3 = −0.03, p-value = 0.14) and the primary cigarette smoking rate (β2 = 0.03, p-value = 0.10; β3 = 0.008, p-value = 0.15) showed no significant changes in the sampled period. Although analyses stratified by sex showed that the allowance of municipal ordinances resulted in reduced SHS exposure in the workplace for both males and females, they did not affect the primary cigarette smoking rate as much, especially among females.ConclusionStrengthening the role of local governments by giving them the authority to enact and enforce penalties on SHS exposure violation helped ROK to reduce SHS exposure in the workplace. However, smoking behaviors and related activities seemed to shift to less restrictive areas such as on the streets and in apartment hallways, negating some of the effects due to these ordinances. Future studies should investigate how smoke-free policies beyond public places can further reduce the SHS exposure in ROK
Novel Neural Network Applications to Mode Choice in Transportation: Estimating Value of Travel Time and Modelling Psycho-Attitudinal Factors
Whenever researchers wish to study the behaviour of individuals choosing among a set of alternatives, they usually rely on models based on the random utility theory, which postulates that the single individuals modify their behaviour so that they can maximise of their utility. These models, often identified as discrete choice models (DCMs), usually require the definition of the utilities for each alternative, by first identifying the variables influencing the decisions. Traditionally, DCMs focused on observable variables and treated users as optimizing tools with predetermined needs. However, such an approach is in contrast with the results from studies in social sciences which show that choice behaviour can be influenced by psychological factors such as attitudes and preferences. Recently there have been formulations of DCMs which include latent constructs for capturing the impact of subjective factors. These are called hybrid choice models or integrated choice and latent variable models (ICLV). However, DCMs are not exempt from issues, like, the fact that researchers have to choose the variables to include and their relations to define the utilities. This is probably one of the reasons which has recently lead to an influx of numerous studies using machine learning (ML) methods to study mode choice, in which researchers tried to find alternative methods to analyse travellers’ choice behaviour. A ML algorithm is any generic method that uses the data itself to understand and build a model, improving its performance the more it is allowed to learn. This means they do not require any a priori input or hypotheses on the structure and nature of the relationships between the several variables used as its inputs. ML models are usually considered black-box methods, but whenever researchers felt the need for interpretability of ML results, they tried to find alternative ways to use ML methods, like building them by using some a priori knowledge to induce specific constrains. Some researchers also transformed the outputs of ML algorithms so that they could be interpreted from an economic point of view, or built hybrid ML-DCM models. The object of this thesis is that of investigating the benefits and the disadvantages deriving from adopting either DCMs or ML methods to study the phenomenon of mode choice in transportation. The strongest feature of DCMs is the fact that they produce very precise and descriptive results, allowing for a thorough interpretation of their outputs. On the other hand, ML models offer a substantial benefit by being truly data-driven methods and thus learning most relations from the data itself. As a first contribution, we tested an alternative method for calculating the value of travel time (VTT) through the results of ML algorithms. VTT is a very informative parameter to consider, since the time consumed by individuals whenever they need to travel normally represents an undesirable factor, thus they are usually willing to exchange their money to reduce travel times. The method proposed is independent from the mode-choice functions, so it can be applied to econometric models and ML methods equally, if they allow the estimation of individual level probabilities. Another contribution of this thesis is a neural network (NN) for the estimation of choice models with latent variables as an alternative to DCMs. This issue arose from wanting to include in ML models not only level of service variables of the alternatives, and socio-economic attributes of the individuals, but also psycho-attitudinal indicators, to better describe the influence of psychological factors on choice behaviour. The results were estimated by using two different datasets. Since NN results are dependent on the values of their hyper-parameters and on their initialization, several NNs were estimated by using different hyper-parameters to find the optimal values, which were used to verify the stability of the results with different initializations
Analytical validation of innovative magneto-inertial outcomes: a controlled environment study.
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