A Bayesian space–time model for clustering areal units based on their disease trends

Population-level disease risk across a set of non-overlapping areal units varies in space and time, and a large research literature has developed methodology for identifying clusters of areal units exhibiting elevated risks. However, almost no research has extended the clustering paradigm to identify groups of areal units exhibiting similar temporal disease trends. We present a novel Bayesian hierarchical mixture model for achieving this goal, with inference based on a Metropolis-coupled Markov chain Monte Carlo ((MC) 3 ) algorithm. The effectiveness of the (MC) 3 algorithm compared to a standard Markov chain Monte Carlo implementation is demonstrated in a simulation study, and the methodology is motivated by two important case studies in the United Kingdom. The first concerns the impact on measles susceptibility of the discredited paper linking the measles, mumps, and rubella vaccination to an increased risk of Autism and investigates whether all areas in the Scotland were equally affected. The second concerns respiratory hospitalizations and investigates over a 10 year period which parts of Glasgow have shown increased, decreased, and no change in risk

Feature discovery and visualization of robot mission data using convolutional autoencoders and Bayesian nonparametric topic models

The gap between our ability to collect interesting data and our ability to analyze these data is growing at an unprecedented rate. Recent algorithmic attempts to fill this gap have employed unsupervised tools to discover structure in data. Some of the most successful approaches have used probabilistic models to uncover latent thematic structure in discrete data. Despite the success of these models on textual data, they have not generalized as well to image data, in part because of the spatial and temporal structure that may exist in an image stream. We introduce a novel unsupervised machine learning framework that incorporates the ability of convolutional autoencoders to discover features from images that directly encode spatial information, within a Bayesian nonparametric topic model that discovers meaningful latent patterns within discrete data. By using this hybrid framework, we overcome the fundamental dependency of traditional topic models on rigidly hand-coded data representations, while simultaneously encoding spatial dependency in our topics without adding model complexity. We apply this model to the motivating application of high-level scene understanding and mission summarization for exploratory marine robots. Our experiments on a seafloor dataset collected by a marine robot show that the proposed hybrid framework outperforms current state-of-the-art approaches on the task of unsupervised seafloor terrain characterization.Comment: 8 page

Spatial clustering of average risks and risk trends in Bayesian disease mapping

Spatiotemporal disease mapping focuses on estimating the spatial pattern in disease risk across a set of nonoverlapping areal units over a fixed period of time. The key aim of such research is to identify areas that have a high average level of disease risk or where disease risk is increasing over time, thus allowing public health interventions to be focused on these areas. Such aims are well suited to the statistical approach of clustering, and while much research has been done in this area in a purely spatial setting, only a handful of approaches have focused on spatiotemporal clustering of disease risk. Therefore, this paper outlines a new modeling approach for clustering spatiotemporal disease risk data, by clustering areas based on both their mean risk levels and the behavior of their temporal trends. The efficacy of the methodology is established by a simulation study, and is illustrated by a study of respiratory disease risk in Glasgow, Scotland

Bayesian nonparametric models for spatially indexed data of mixed type

We develop Bayesian nonparametric models for spatially indexed data of mixed type. Our work is motivated by challenges that occur in environmental epidemiology, where the usual presence of several confounding variables that exhibit complex interactions and high correlations makes it difficult to estimate and understand the effects of risk factors on health outcomes of interest. The modeling approach we adopt assumes that responses and confounding variables are manifestations of continuous latent variables, and uses multivariate Gaussians to jointly model these. Responses and confounding variables are not treated equally as relevant parameters of the distributions of the responses only are modeled in terms of explanatory variables or risk factors. Spatial dependence is introduced by allowing the weights of the nonparametric process priors to be location specific, obtained as probit transformations of Gaussian Markov random fields. Confounding variables and spatial configuration have a similar role in the model, in that they only influence, along with the responses, the allocation probabilities of the areas into the mixture components, thereby allowing for flexible adjustment of the effects of observed confounders, while allowing for the possibility of residual spatial structure, possibly occurring due to unmeasured or undiscovered spatially varying factors. Aspects of the model are illustrated in simulation studies and an application to a real data set

Modeling and estimation of multi-source clustering in crime and security data

While the presence of clustering in crime and security event data is well established, the mechanism(s) by which clustering arises is not fully understood. Both contagion models and history independent correlation models are applied, but not simultaneously. In an attempt to disentangle contagion from other types of correlation, we consider a Hawkes process with background rate driven by a log Gaussian Cox process. Our inference methodology is an efficient Metropolis adjusted Langevin algorithm for filtering of the intensity and estimation of the model parameters. We apply the methodology to property and violent crime data from Chicago, terrorist attack data from Northern Ireland and Israel, and civilian casualty data from Iraq. For each data set we quantify the uncertainty in the levels of contagion vs. history independent correlation.Comment: Published in at http://dx.doi.org/10.1214/13-AOAS647 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org