665,040 research outputs found

    The 5C 6 and 5C 7 surveys of radio sources

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    5C 6 and 5C 7 continue the series of deep surveys made at 408 and 1407 MHz with the One-Mile telescope at Cambridge. They were intended (1) to provide a sample of faint radio sources suitable for further study; (2) to improve the statistics of source counts N(S) and spectral-index distributions at low flux densities; (3) to study the isotropy of the distribution of faint sources. Each observed field is about 4° in diameter at 408 MHz and 1° in diameter at 1407 MHz, and the field-centres are a α = 02ʰ14ᵐ, δ = 32° (5C 6) and α = 08ᵏ17ᵐ, δ = 27° (5C 7). The synthesized beamwidths (FWHM) are 80 arcsec (408 MHz) and 23 arcsec (1407 MHz). The techniques of observation and data-analysis followed closely those used for 5C 5 (Pearson, T. J., 1975. Mon. Not. R. astr. Soc., 171, 475), with some minor variations which are noted in Section 2

    Dependence receptor involvement in subtilisin-induced long-term depression and in long-term potentiation

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    The serine protease subtilisin induces a form of long-term depression (LTD) which is accompanied by a reduced expression of the axo-dendritic guidance molecule Unco-ordinated-5C (Unc-5C). One objective of the present work was to determine whether a loss of Unc-5C function contributed to subtilisin-induced LTD by using Unc-5C antibodies in combination with the pore-forming agents Triton X-100 (0.005%) or streptolysin O in rat hippocampal slices. In addition we have assessed the effect of subtilisin on the related dependence receptor Deleted in Colorectal Cancer (DCC) and used antibodies to this protein for functional studies. Field excitatory postsynaptic potentials (fEPSPs) were analysed in rat hippocampal slices and protein extracts were used for Western blotting. Subtilisin produced a greater loss of DCC than of Unc-5C, but the antibodies had no effect on resting excitability or fEPSPs and did not modify subtilisin-induced LTD. However, antibodies to DCC but not Unc-5C did reduce the amplitude of theta-burst long-term potentiation (LTP). In addition, two inhibitors of endocytosis – dynasore and tat-gluR2(3Y) – were tested and, although the former compound had no effect on neurophysiological responses, tat-gluR2(3Y) did reduce the amplitude of subtilisin-induced LTD without affecting the expression of DCC or Unc-5C but with some loss of PostSynaptic Density Protein-95. The results support the view that the dependence receptor DCC may be involved in LTP and suggest that the endocytotic removal of a membrane protein or proteins may contribute to subtilisin-induced LTD, although it appears that neither Unc-5C nor DCC are involved in this process. (220)

    Spontaneous dehydrocoupling in peri-substituted phosphine-borane adducts

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    This work was financially supported by the EPSRC and COST action CM1302 SIPs.Bis(borane) adducts Acenap(PiPr2·BH3)(PRH·BH3) (Acenap = acenaphthene-5,6-diyl; 4a, R = Ph; 4b, R = ferrocenyl, Fc; 4c, R = H) were synthesised by the reaction of excess H3B·SMe2 with either phosphino-phosphonium salts [Acenap(PiPr2)(PR)]+Cl− (1a, R = Ph; 1b, R = Fc), or bis(phosphine) Acenap(PiPr2)(PH2) (3). Bis(borane) adducts 4a–c were found to undergo dihydrogen elimination at room temperature, this spontaneous catalyst-free phosphine-borane dehydrocoupling yields BH2 bridged species Acenap(PiPr2)(µ-BH2)(PR·BH3) (5a, R = Ph; 5b, R = Fc; 5c, R = H). Thermolysis of 5c results in loss of the terminal borane moiety to afford Acenap(PiPr2)(µ-BH2)(PH) (14). Single crystal X-ray structures of 3, 4b and 5a–c are reported.Publisher PDFPeer reviewe

    Positive allosteric binding behavior of pyrene-appended triazole-modified thiacalix[4]arene-based fluorescent receptors

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    The novel heteroditopic receptors 5a∼c have been synthesized, which bear a thiacalix[4]arene in the 1,3-alternate conformation. Two urea moieties possessing various aryl groups with either electron-donating or -withdrawing groups at their p-positions function as anion-binding sites. At the opposite side of the cavity are two pyrene-appended triazole rings, which act as cation-binding sites. The binding property of receptor 5c was investigated by means of 1H NMR and UV–vis spectroscopy and by fluorescence titration experiments in the presence of various transition metal cations and anions in CH2Cl2–DMSO (10:1, v/v) solution. Interestingly, it was found that receptor 5c possessing two p-nitrophenyl ureido moieties, most efficiently complexes in the urea cavity or bistriazoles; the plausible allosteric effect of receptor 5c was also investigated

    Estimation of N-acetyltransferase 2 haplotypes

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    N-Acetyltransferase 2 (NAT2) genotyping may result in a considerable percentage in several ambiguous allele combinations. PHASE 2.1 is a statistical program which is designed to estimate the probability of different allele combinations. We have investigated haplotypes of 2088 subjects genotyped for NAT2 according to standard PCR/RFLP methods. In 856 out of 2088 cases the genotype was clearly defined by PCR/RFLP only. In many of the remaining cases the program clearly defined the most probable allele combination: In the case of *5A/*6C, *5B/*6A the probability for *5B/*6A is 99% whereas the alternative allele combination *5A/*6C can be neglected. Other combinations cannot be allocated with a comparable high probability. For example the allele combination *5A/*5C, *5B/*5D provides for *5A/*5C a probability of 69% whereas the estimation for *5B/*5D allele is only 31%. In the two most often observed constellations in our data [(*12A/*5B, *12C/*5C); (*12A/*6A, *12B/*6B, *4/*6C)] the probability of allele combination was ascertained as follows: *12A/*5B, 98%; *12C/*5C, 1.4% and *12A/*6A, 82%; *4/*6C, 17%; *12B/*6B, 0%. The estimation of the NAT2 haplotype is important because the assignment of the NAT2 alleles *12A, *12B or *13 as a rapid or slow genotype has been discussed controversially. Otherwise the classification of alleles in subjects which are not showing a clearly allocation can result in a rapid or slow acetylation state. This assignment has an important role in survey of bladder cancer cases in the scope of occupational exposure with aromatic amines. --PHASE 2.1,NAT2 genotyping,single nucleotide polymorphism

    Author Correction: The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms.

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    The originally published version of this Article contained errors in Figure 5, for which we apologise. In panel c, the scatter graph was inadvertently replaced with a scatter graph comprising a subset of data points from panel d. Furthermore, the legends to Figures 5c and 5d were inverted. These errors have now been corrected in both the PDF and HTML versions of the Article, and the incorrect version of Fig. 5c is presented in the Author Correction associated with this Article

    Light-Front Approach for Pentaquark Strong Decays

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    Assuming the two diquark structure for the pentaquark state as advocated in the Jaffe-Wilczek model, we study the strong decays of light and heavy parity-even pentaquark states using the light-front quark model in conjunction with the spectator approximation. The narrowness of the Theta width is ascribed to the p-wave configuration of the diquark pair. Taking the Theta width as a benchmark, we estimate the rates of the strong decays Xi_{3/2}-- to Xi- pi-, Sigma- K-, Sigma_{5c}0 to D_s- p, D_{s0}*- p and Xi_{5c}0 to D_s- Sigma+, D_{s0}^{*-} Sigma+ with Sigma_{5c} Xi_{5c} being antisextet charmed pentaquarks and D_{s0}* a scalar strange charmed meson. The ratio of Gamma(P_c to Baryon D_{s0}*)/Gamma(P_c to Baryon D_s) is very useful for verifying the parity of the antisextet charmed pentaquark P_c. It is expected to be of order unity for an even parity P_c and much less than one for an odd parity pentaquark.Comment: 24 pages, 2 figure

    Pengaruh Penyuluhan terhadap Pengetahuan dan Sikap 5R (Ringkas, Rapi, Resik, Rawat, Rajin) pada Tenaga Kerja di Sentra Industri Pengrajin Blangkon Serengan Surakarta

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    The application of 5C be applied throughout the industrial sector, both formal and informal industry. Lack of information on 5C in the industrial sector informal impact on the lack of knowledge and attitude 5C on workers. The purpose of this research was to analyze the influence of councelling to knowledge and attitude about 5C on mployee’s blangkon industry centre, Serengan Surakarta. This research’s method used quasi experimental by one group pretest and posttest. The population in this research was blangkon craftsman employee’s about 88 workers. The sample technique used proportional sampling technique as many as 47 respondents. The result of this research showed an increase in the average score at the knowledge before and after treatment as many as 44.2 %. In the attitude showed an increase in the average score before and after treatment as many as 54.3 %. The results of statistical tests used wilcoxon on knowledge shows p value 0.000 and in the attitude of shows p value 0.000 wich mean ≤ 0.05, so it can be concluded that there is influence of counselling to the knowledge and attitude about 5C on employee’s blangkon industry centre, Serengan Surakarta. The advice to employee’s is to be more enterprising in the tracery of related information about 5C so can be applied 5C at work place and to the government to conduct counselling further so that employee’s can understand more about the purposes of 5C. Keywords : Councelling, 5C ( Clear-out, Configure, Clean, Conform, Custom ), Knowledge, Attitude

    Basic a final exam v4

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    Written exam for students who have completed Units 5C to 9D in the Face2Face Elementary Series published by Cambridge University Press

    ANALISIS PEIIEBAPAI{ PRINSIP 5C PAI}A PE}TYALTJRAN PEMBIAYAAN DI BANK SYARI'AH (Studi pada Bank BJB Syar'ah Arjawinangun Cirebon)

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    NINIK NIHAYAH NIM.14112220181 “ANALISIS PENERAPAN PRINSIP 5C PADA PENYALURAN PEMBIAYAAN DI BANK SYARI’AH (Studi pada Bank BJB Syar’ah Arjawinangun Cirebon)”, Skripsi 2015. Dalam pemberian pembiayaan terdapat beberapa analisis yang harus dilakukan bank kepada nasabah, ini semua dilakukan agar tidak terjadi hal-hal yang tidak diinginkan, seperti pembayaran pembiayaan yang kurang lancar atau bahkan pembiayaan yang bermasalah (kredit macet). Salah satunya adalah menggunakan analisis penerapan asas 5C (The Five C‟s of Credit Analysis). prinsip ini diterapkan agar meminimalisir terjadinya pembiayaan bermasalah. Dalam penelitian ini dirumuskan masalah yang terkait dengan judul diatas yakni: Bagaimana prosedur penerapan prinsip 5C pada penyaluran pembiayaan pada bank BJB Syari‟ah Cabang Arjawinangun? Bagaimana efektivitas penerapan prinsip 5C terhadap kualitas produk pembiayaan pada bank BJB Syari‟ah Cabang Arjawinangun? Tujuan dalam penelitian ini adalah untuk menganalisis penerapan prinsip 5C pada penyaluran pembiayaan. obyek penelitian yaitu Bank BJB Syari'ah Arjawinangun. metode yang digunakan dalam penelitian ini kualitatif yang bersifat deskriptif. teknik pengumpulan data dilakukan dengan menganalisis data melalui observasi, studi kepustakaan dan melakukan wawancara dengan pihak analisis kredit Bank BJB Syari'ah Arjawinangun. Dari hasil penelitian ini dapat dikatakan bahwa prosedur penerapan prinsip 5C (Character, Capacity, Capital, Condition of Economy, Colleteral) yang diterapkan dalam BJB Syari'ah ini diterapkan hampir 100%. Hal ini dapat dilihat dari cara seorang analisis menganalisis calon nasabah, dimana dalam penerapan prinsip 5C ini seorang analisis menganalisis calon nasabah mulai dari karakternya calon nasabah, kemudian kemampuan calon nasabah untuk mengembalikan pembiayaaannya, modal yang dimiliki calon nasabah pembiayaan, dimana bank akan lebih yakin menyalurkan pembiayaan ketika modal calon nasabah yang dimiliki lebih besar dari pada pembiayaaan yang akan diajukan kepada bank, karena lebih banyak modal yang nasabah miliki maka nasabah ini akan jauh lebih sungguh-sungguh dalam mengelola usahanya. Kemudian Condition of Economy, diprinsip ini yang berperan sangat penting adalah analisis pembiayaannya, karena seorang analisis harus bisa membaca apa yang akan terjadi dalam dunia polotik, ekonomi dan lain-lain ini semua ditujukan agar meminimalisisr terjadinya pembiayaan macet atau kredit macet. Colleteral (jaminan) dalam prinsip 5C bank BJB Syari‟ah Arjawinangun menempatkan posisi colleteral pada point terahir, dimana jaminan ini hanya akan dikeluarkan ketika calon nasabah pembiayaannya macet. Tetapi di Bank BJB Syari‟ah Arjawinangun ini lebih menekankan pada prinsip karakter, dimana jika seseorang memiliki karakter yang baik tentunya nasabah juga mempunyai i'tikad yang baik untuk mengembalikan pembiayaan yang telah dipinjamnya itu. kemudian Dalam penerapan prinsip 5C Bank BJB Syari‟ah Arjawinangun menerapkan ke dalam produk-produk Pembiayaan yang produktif maupun yang konsumtif, dan dalam penerapan ke dalam produk pembiayaannya sudah efektif, sehingga kualitas dari produk pembiayaan bank BJB Syari‟ah cabang Arjawinangun sudah dikatakan baik. Kata Kunci: Analisis Prinsip 5c, Penyaluran pembiayaa
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