132,469 research outputs found

    Using the information of cosmic rays to predict influence epidemic

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    A correlation between the incidence of influenza pandemics and increased cosmic ray activity is made. A correlation is also made between the occurrence of these pandemics and the appearance of bright novae, e.g., Nova Eta Car. Four indices based on increased cosmic ray activity and novae are proposed to predict future influenza pandemics and viral antigenic shifts

    Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders

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    Industrialized society currently faces a wide range of non-infectious, immune-related pandemics. These pandemics include a variety of autoimmune, inflammatory and allergic diseases that are often associated with common environmental triggers and with genetic predisposition, but that do not occur in developing societies. In this review, we briefly present the idea that these pandemics are due to a limited number of evolutionary mismatches, the most damaging being ‘biome depletion’. This particular mismatch involves the loss of species from the ecosystem of the human body, the human biome, many of which have traditionally been classified as parasites, although some may actually be commensal or even mutualistic. This view, evolved from the ‘hygiene hypothesis’, encompasses a broad ecological and evolutionary perspective that considers host-symbiont relations as plastic, changing through ecological space and evolutionary time. Fortunately, this perspective provides a blueprint, termed 'biome reconstitution', for disease treatment and especially for disease prevention. Biome reconstitution includes the controlled and population-wide reintroduction (i.e. domestication) of selected species that have been all but eradicated from the human biome in industrialized society and holds great promise for the elimination of pandemics of allergic, inflammatory and autoimmune diseases

    Past Influenza pandemics and their effect in Malta

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    The influenza virus type A has caused repeated pandemics throughout the 19th and 20 th century causing significant morbidity and mortality on a worldwide scale. The worst pandemic on record during the 20th century was that which occurred during 1917-19, the virus being assisted in its spread by the massive movement of persons brought on by World War I. The present increasing international travel has led to increasing alarm of the possible effects of an emerging pandemic with the WHO issuing guidelines to ensure the preparedness of health authorities. The various Influenza Type A pandemics of the late 19th and 20th century have had a varying effect on the Maltese community with influenza reaching epidemic proportions during the 1889-90 Asiatic Flu, 1917-19 Spanish Flu, 1957-58 Asian Flu pandemics, and 1968-69 Hong Kong flu, but no apparent effect during the 1977-78 Russian Flu pandemic.peer-reviewe

    What country, university or research institute, performed the best on COVID-19? Bibliometric analysis of scientific literature

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    In this article, we conduct data mining to discover the countries, universities and companies, produced or collaborated the most research on Covid-19 since the pandemic started. We present some interesting findings, but despite analysing all available records on COVID-19 from the Web of Science Core Collection, we failed to reach any significant conclusions on how the world responded to the COVID-19 pandemic. Therefore, we increased our analysis to include all available data records on pandemics and epidemics from 1900 to 2020. We discover some interesting results on countries, universities and companies, that produced collaborated most the most in research on pandemic and epidemics. Then we compared the results with the analysing on COVID-19 data records. This has created some interesting findings that are explained and graphically visualised in the article

    Prediction and prevention of the next pandemic zoonosis.

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    Most pandemics--eg, HIV/AIDS, severe acute respiratory syndrome, pandemic influenza--originate in animals, are caused by viruses, and are driven to emerge by ecological, behavioural, or socioeconomic changes. Despite their substantial effects on global public health and growing understanding of the process by which they emerge, no pandemic has been predicted before infecting human beings. We review what is known about the pathogens that emerge, the hosts that they originate in, and the factors that drive their emergence. We discuss challenges to their control and new efforts to predict pandemics, target surveillance to the most crucial interfaces, and identify prevention strategies. New mathematical modelling, diagnostic, communications, and informatics technologies can identify and report hitherto unknown microbes in other species, and thus new risk assessment approaches are needed to identify microbes most likely to cause human disease. We lay out a series of research and surveillance opportunities and goals that could help to overcome these challenges and move the global pandemic strategy from response to pre-emption

    Epidemics and pandemics : Covid-19 and the ‘‘drop of honey effect’’

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    Purpose: The aim of this paper is the use of the “drop of honey effect” to explain the spread of Covid-19. Approach/Methodology/Design: After Covid-19 appearance in Wuhan, in the Chinese province of Hubei, by December, 2019, it spread all over the world. The World Health Organization declared it as pandemic in March 11, 2020. The infection is highly contagious and made thousands of deaths around the world. Timely decisions are key for the control of the dissemination. The “drop of honey effect” results as an important framework to explain the Covid-19 spread. Findings: An opportune decision in a very initial moment could have made all the difference in the virus spread. Practical Implications: The study will contribute positively for the understanding of the importance of well-timed decisions for governments, world organizations, academia, companies and people, each one on a different dimension’s level. Originality/Value: This study presents the “drop of honey effect” as an original and very suitable framework to explain the way how the virus spread all over the world after the virus in Wuhan began to infect people.peer-reviewe

    Global Health Security in an Era of Explosive Pandemic Potential

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    Pandemics pose a significant risk to security, economic stability, and development. Annualized expected losses from pandemics are estimated at 60billionperyear.Despitethecertaintyandmagnitudeofthethreat,theglobalcommunityhassignificantlyunderestimatedandunderinvestedinavoidanceofpandemicthreats.Wecannotwaitorcontinuewiththestatusquo,inwhichwepayattentiontoinfectiousdiseasethreatsonlywhentheyareattheirpeakandthenarecomplacentandremainvulnerableuntilthenextmajoroutbreak.Toreinforceandsustaininternationalfocus,funding,andaction,itiscrucialthatpandemicsrisetothelevelofhighpolitics,becomingstandingagendaitemsforpoliticalactors.Inthisarticle,wemakethecaseforfundamentalreformoftheinternationalsystemtosafeguardglobalhealthsecurity.WebuildontheactionagendaofferedbyfourinternationalcommissionsformedinthewakeoftheEbolaepidemic,callingfortherecommendedpeacedividend(anannualincrementalinvestmentof60 billion per year. Despite the certainty and magnitude of the threat, the global community has significantly underestimated and underinvested in avoidance of pandemic threats. We cannot wait or continue with the status quo, in which we pay attention to infectious disease threats only when they are at their peak and then are complacent and remain vulnerable until the next major outbreak. To reinforce and sustain international focus, funding, and action, it is crucial that pandemics rise to the level of “high politics,” becoming standing agenda items for political actors. In this article, we make the case for fundamental reform of the international system to safeguard global health security. We build on the action agenda offered by four international commissions formed in the wake of the Ebola epidemic, calling for the recommended “peace dividend” (an annual incremental investment of 4.5 billion – 65 cents per person) to strengthen global preparedness, for the United Nations to play a greater role in responding to major global health and humanitarian emergencies, and for an effective and efficient R&D strategy with multiple stakeholders—governments, academics, industry, and civil society—identifying R&D priorities and leading a coordinated response. If our action plan were adopted, it would safeguard the global population far better against infectious disease threats. It would reap dividends in security, development, and productivity
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