1,575 research outputs found
Racial Ethnic Equality in Child Well-Being from 1985-2004: Gaps Narrowing, but Persist
Analyzes changes in safety/behavioral concerns, family economic well-being, health, community connectedness, educational attainment, social relationships, and emotional/spiritual well-being by race and ethnicity. Tracks disparities between groups
Young Children of Immigrants: The Leading Edge of America's Future
Highlights data on the population of children of immigrants up to age 8, distribution by state, parents' origins, school enrollment rates, English proficiency, and family characteristics, including parent's citizenship, education, and income level
Children in Immigrant Families - The U.S. and 50 States: Economic Need Beyond the Official Poverty Measure
Analyzes gaps between child poverty rates in immigrant families and native-born families based on two alternative measures that take into account the costs of housing, food, other basic necessities, transportation, taxes, child care, and early education
Children in Immigrant Families -- The U.S. and 50 States: National Origins, Language, and Early Education
Draws on new results of U.S. Census 2000 data to focus on children in immigrant families, highlighting the proportion, dispersion, national origins, language, and early education of children in newcomer families nationwide and in various states
A Profile of Immigrants in Arkansas
Discusses key demographic trends, economic factors, and public policy issues associated with immigrants in Arkansas, which has the fourth-fastest-growing immigrant population in the nation
Ameliorating Systematic Uncertainties in the Angular Clustering of Galaxies: A Study using SDSS-III
We investigate the effects of potential sources of systematic error on the
angular and photometric redshift, z_phot, distributions of a sample of redshift
0.4 < z < 0.7 massive galaxies whose selection matches that of the Baryon
Oscillation Spectroscopic Survey (BOSS) constant mass sample. Utilizing over
112,778 BOSS spectra as a training sample, we produce a photometric redshift
catalog for the galaxies in the SDSS DR8 imaging area that, after masking,
covers nearly one quarter of the sky (9,913 square degrees). We investigate
fluctuations in the number density of objects in this sample as a function of
Galactic extinction, seeing, stellar density, sky background, airmass,
photometric offset, and North/South Galactic hemisphere. We find that the
presence of stars of comparable magnitudes to our galaxies (which are not
traditionally masked) effectively remove area. Failing to correct for such
stars can produce systematic errors on the measured angular auto-correlation
function, w, that are larger than its statistical uncertainty. We describe how
one can effectively mask for the presence of the stars, without removing any
galaxies from the sample, and minimize the systematic error. Additionally, we
apply two separate methods that can be used to correct the systematic errors
imparted by any parameter that can be turned into a map on the sky. We find
that failing to properly account for varying sky background introduces a
systematic error on w. We measure w, in four z_phot slices of width 0.05
between 0.45 < z_phot < 0.65 and find that the measurements, after correcting
for the systematic effects of stars and sky background, are generally
consistent with a generic LambdaCDM model, at scales up to 60 degrees. At
scales greater than 3 degrees and z_phot > 0.5, the magnitude of the
corrections we apply are greater than the statistical uncertainty in w.Comment: Accepted by MNRA
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
Expansion of the polyglutamine repeat within the protein Huntingtin (Htt) causes Huntington's disease, a neurodegenerative disease associated with aging and the accumulation of mutant Htt in diseased neurons. Understanding the mechanisms that influence Htt cellular degradation may target treatments designed to activate mutant Htt clearance pathways. We find that Htt is phosphorylated by the inflammatory kinase IKK, enhancing its normal clearance by the proteasome and lysosome. Phosphorylation of Htt regulates additional post-translational modifications, including Htt ubiquitination, SUMOylation, and acetylation, and increases Htt nuclear localization, cleavage, and clearance mediated by lysosomal-associated membrane protein 2A and Hsc70. We propose that IKK activates mutant Htt clearance until an age-related loss of proteasome/lysosome function promotes accumulation of toxic post-translationally modified mutant Htt. Thus, IKK activation may modulate mutant Htt neurotoxicity depending on the cell's ability to degrade the modified species
A Cautionary Tale: MARVELS Brown Dwarf Candidate Reveals Itself To Be A Very Long Period, Highly Eccentric Spectroscopic Stellar Binary
We report the discovery of a highly eccentric, double-lined spectroscopic
binary star system (TYC 3010-1494-1), comprising two solar-type stars that we
had initially identified as a single star with a brown dwarf companion. At the
moderate resolving power of the MARVELS spectrograph and the spectrographs used
for subsequent radial-velocity (RV) measurements (R ~ <30,000), this particular
stellar binary mimics a single-lined binary with an RV signal that would be
induced by a brown dwarf companion (Msin(i)~50 M_Jup) to a solar-type primary.
At least three properties of this system allow it to masquerade as a single
star with a very low-mass companion: its large eccentricity (e~0.8), its
relatively long period (P~238 days), and the approximately perpendicular
orientation of the semi-major axis with respect to the line of sight (omega~189
degrees). As a result of these properties, for ~95% of the orbit the two sets
of stellar spectral lines are completely blended, and the RV measurements based
on centroiding on the apparently single-lined spectrum is very well fit by an
orbit solution indicative of a brown dwarf companion on a more circular orbit
(e~0.3). Only during the ~5% of the orbit near periastron passage does the
true, double-lined nature and large RV amplitude of ~15 km/s reveal itself. The
discovery of this binary system is an important lesson for RV surveys searching
for substellar companions; at a given resolution and observing cadence, a
survey will be susceptible to these kinds of astrophysical false positives for
a range of orbital parameters. Finally, for surveys like MARVELS that lack the
resolution for a useful line bisector analysis, it is imperative to monitor the
peak of the cross-correlation function for suspicious changes in width or
shape, so that such false positives can be flagged during the candidate vetting
process.Comment: 16 pages, 11 figures, 6 table
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