Graph Theoretical Modeling of Self-Assembling DNA of the Double Cone Graph

Abstract

The unique properties of double-stranded DNA molecules make DNA a valuable structural material with which to form nanostructures, and the field of DNA nanotechnology is largely based on this premise. By modeling nanostructures with discrete graphs, efficient DNA self-assembly becomes a mathematical puzzle. These nanostructures have wide-ranging applications, such as containers for the transport and release of nano-cargos, templates for the controlled growth of nano-objects, and in drug-delivery methods. This research centers around exploring graph theoretical and combinatorial properties of DNA self-assembly to optimize the nanostructure construction for the Double Cone Graph