A new chemotype that opens the S2∗ pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2

Mourot, Laura; Chaibi, Fatima-Zahra; Bou-Karroum, Nour; Carré, Paul; Abengozar Munoz, Alberto; Landry, Valérie; Tarricone, Audrey; Biela, Alexandre; Piveteau, Catherine; Novikov, Gleb; Dupré, Elian; Dubuisson, Jean; Belouzard, Sandrine; Leroux, Florence; Deprez, Benoit; Hanoulle, Xavier; Charton, Julie

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oai:HAL:hal-05478824v1

A new chemotype that opens the S2∗ pocket of the 3CL protease exhibits antiviral activity against SARS-CoV-2

Authors: Laura Mourot
Fatima-Zahra Chaibi
Nour Bou-Karroum
Paul Carré
Alberto Abengozar Munoz
Valérie Landry
Audrey Tarricone
Alexandre Biela
Catherine Piveteau
Gleb Novikov
Elian Dupré
Jean Dubuisson
Sandrine Belouzard
Florence Leroux
Benoit Deprez
Xavier Hanoulle
Julie Charton
Publication date: 1 January 2026
Publisher: Elsevier
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Last time updated on 05/03/2026

This paper was published in HAL - RIIP.

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