植物精油成分の駆虫作用に関する研究 第3報 「マウス」に対する毒性と蛔虫および蚯蚓筋に対する作用との関係

Abstract

Toxicity for mice was compared with stimulating effects on isolated earthworm muscles and ascaricidal properties of the following compounds; safrol, iso-safrol, dihydro-eugenol, carvacrol, chlorthvmol 1inalool, terpineol, eucalyptol, geraniol, citronellol, menthoglycol and d-limonone. 1. No definite relationship can he perceived between toxicity for mice and the stimulating action on earthworm muscles. 2. Large does of these compounds cause either convulsions or paralysis in mice. 3. Generally speaking, toxicity for mice does not always run parallel with the ascaricidal properties. However, in regard to the compounds which produce convulsive toxic effects on mice, there seems to he a parallel between toxicites for mice and pig ascaris