Determination of antibiotics susceptibility pattern of some Enterobacteriaceae associated with acute diarrhea among children in Kano, Nigeria

Abstract

The study was aimed to determination of antibiotics susceptibility pattern of some enteric bacteria associated with diarrhea among children in Kano, Northern Nigeria. In the Study, total of two hundred and fifty samples (250) from the study subjects were examined. Enteric bacteria were isolated and identified using conventional methods while the identified isolates were screened for antibiotic susceptibility testing using agar disc diffusion method. Total of 523 Enterobacteriaceae isolates identified were subjected to multi drug resistance (MDR) test, of which 27 (5.2%) isolates were resistant to four or more antibiotics tested while 496 (94.8%) of the isolates were resistant to less than four antibiotics. E. coli showed high resistant to streptomycin (63.2%) and chloramphenicol (23.8%). Salmonella was resistant to streptomycin (78.3%), gentamicin (61.9%) and erythromycin (33.7%) while Shigella spp were resistant to streptomycin (74.6%), gentamicin (76.6%) and ampicillin (54%). On the other hand, E. coli demonstrated sensitivity to ciprofloxacin (92.8%), tetracycline (92.8%), augmentin (90.7%) and nalidixic acid (94.8%). Salmonella spp was highly sensitive to augmentin (96.8%), nalidixic acid (93.5%), tetracycline (91.3) and ciprofloxacin (93.5%) while Shigella spp was sensitive to nalidixic acid (93.7%), chloramphenicol (93.7%) and ciprofloxacin (83%). The antibiotic resistance exists among enteric bacteria associated with diarrhea in children