Optical applications of Terahertz/Infrared spectroscopy for the detection of biomolecules

Abstract

Biomedical and biophysical science is one of the most significant research fields in the 21st century. Several techniques are used for studying biomolecules dynamics and biosystems (generally not in their physiological environment), e.g., magnetic resonance, fluorescence imaging techniques, vibrational and acoustics spectroscopy and biochemical assays. Among them, one of the most important technique is the Terahertz Infrared (THz/IR) spectroscopy. This PhD project proposes the design and the development of a TH z/IR spectroscopic platform and a novel methodological approach for the detection and study of biomolecules of biological relevance and biosystems. The project is divided in different tasks, as follows (i) Design and Development of a THz /IR spectroscopy setups , (ii) evaluation of its performances, (iii) conceptualization and comparison of THz/IR spectroscopy for biomolecules and biosystems of interest