A clinico-epidemiological investigation of human Leptospirosis in the Panhala hill area of Maharashtra, focusing on agricultural and dairy farm-A Population Based Case Control Study

Abstract

Doi: 10.5281/zenodo.11070962 The clinico-epidemiological study, which focused on agricultural and dairy settings in the Panhala hill area of Maharashtra, was a beneficial method to studying the dynamics of human leptospirosis in that particular location. A population-based case-control research can shed light on the disease's risk factors and assist guide focused efforts for prevention and treatment. In this study, we enroll individuals who have been diagnosed with leptospirosis (cases) and compare them with a control group of individuals without the disease. The study aim to collect data on various clinico-epidemiological factors to determine potential associations and risk factors for leptospirosis in the agricultural and dairy settings of the Panhala hill area. For the age group and gender, a total of 22 confirmed cases of leptospirosis were documented. Of the cases, the age group of 36–56 years accounted for 60% of them, followed by 15–35 years (40.9%) and 56+ years (12.5%). More than 81.81% lived in rural regions, with almost 68.18% working as farmers, followed by animal husbandry (22.72%) and daily wage jobs (9.09%) such as dairy work. In control there were Males 20 and 24 females. By conducting a clinico-epidemiological investigation in the Panhala hill area, researchers can gain a better understanding of the local dynamics of leptospirosis transmission, identify specific risk factors in agricultural and dairy settings, and develop evidence-based strategies for prevention and control. The findings from such a study can contribute to the overall knowledge and public health response to leptospirosis in the region