RNA processing and ribosome biogenesis in bone marrow failure dsorders: DOI: 10.14800/rd.1531

William Blalock, Manuela Piazzi, Angela Gallo, Alberto Bavelloni, Enrico Focaccia, Irene Faenza

research article

oai:ojs.pkp.sfu.ca:article/243

RNA processing and ribosome biogenesis in bone marrow failure dsorders: DOI: 10.14800/rd.1531

Authors: Manuela Piazzi, Angela Gallo, Alberto Bavelloni, Enrico Focaccia, Irene Faenza William Blalock
Publication date: 3 April 2019
Publisher: Smart Science & Technology LLC, USA

Abstract

Bone marrow failure disorders (BMFDs), which are characterized by an early pro-apoptotic phase which results in faulty hematopoiesis and anemia, more often than not progress to outright acute myelogenous leukemia (AML). Recent findings have indicated that most if not all of these disorders have a very significant RNA processing component to their pathology. This review aims to highlight some of normal processes of RNA metabolism that have been recently demonstrated to be altered in BMFDs

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RNA & DISEASE (E-Journal - Smart Science & Technology)

oai:ojs.pkp.sfu.ca:article/243

Last time updated on 20/12/2022

This paper was published in RNA & DISEASE (E-Journal - Smart Science & Technology).

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