Identification of microRNAs from Atlantic salmon macrophages upon Aeromonas salmonicida infection: DOI: 10.14800/rd.303

Villianur Ibrahim Hairul-Islam, Subramanian Saravanan, Durairaj Sekar, Kulandaivelu Karikalan, Palanisamy Senthilkumar, Ravi Chandrika Chandrika, Krishnaraj Thirugnanasambantham

research article

oai:ojs.pkp.sfu.ca:article/161

Identification of microRNAs from Atlantic salmon macrophages upon Aeromonas salmonicida infection: DOI: 10.14800/rd.303

Authors: Subramanian Saravanan, Durairaj Sekar, Kulandaivelu Karikalan, Palanisamy Senthilkumar, Ravi Chandrika Chandrika, Krishnaraj Thirugnanasambantham Villianur Ibrahim Hairul-Islam
Publication date: 15 October 2014
Publisher: Smart Science & Technology LLC, USA

Abstract

Computational approach was used in to identify potent macrophage specific miRNAs involved in basic biological process of Salmo salar. Analysis of 1119 ESTs from macrophages of Atlantic salmon (Salmo salar) infected with Aeromonas salmonicida revealed expression of 3 miRNAs. Phylogenetic analysis of both the pre-miRNA sequence revealed its evolutionarily conserved nature among various species. Identified targets of the predicted miRNAs revealed the role of miRNA in pathogenesis, stress response and allosteric exchange of histones. Further detailed studies of these miRNAs will help in revealing its function in different biological process necessary for the action of macrophages upon pathogen infection

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RNA & DISEASE (E-Journal - Smart Science & Technology)

oai:ojs.pkp.sfu.ca:article/161

Last time updated on 20/12/2022

This paper was published in RNA & DISEASE (E-Journal - Smart Science & Technology).

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