Complete genome analysis of a novel phage GW1 lysing Cronobacter

Abstract

AbstractA newly identified lytic Cronobacter phage, GW1, was isolated from the Pearl River of Guangzhou, China. GW1 had adouble-stranded DNA genome of 39,695 nucleotides with an average GC content of 53.18 %. Among the 49 open readingframes (ORFs) identified, genes for rRNA, tRNA, antibiotic resistance, and virulence factors were not found in the phagegenome. The morphology, genomic features, and phylogenetic position of GW1 revealed that it represents a new species inthe genus T7virus. This novel lytic Cronobacter phage may provide an alternative for phage therapy and biocontrol againstCronobacter